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科研机构
上海药物研究所 [3]
北京大学 [2]
华中师范大学 [2]
生态环境研究中心 [2]
厦门大学 [1]
大连理工大学 [1]
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内容类型
期刊论文 [13]
学位论文 [1]
发表日期
2021 [1]
2019 [1]
2018 [1]
2015 [3]
2014 [3]
2013 [2]
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Chemistry [1]
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浏览/检索结果:
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Isolation and structure elucidation of polysaccharides from fruiting bodies of mushroom Coriolus versicolor and evaluation of their immunomodulatory effects
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 166, 页码: 1387-1395
作者:
Zhang, Xue
;
Cai, Zhenyu
;
Mao, Haoyu
;
Hu, Pei
;
Li, Xiaojun
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/05/24
Coriolus versicolor
Polysaccharides
Chemical structure
NMR analysis
Methylation
Immunoregulatory effects
Beta-glucan
dynamicmodificationsofbiomacromoleculesmechanismandchemicalinterventions
期刊论文
sciencechinalifesciences, 2019, 卷号: 62, 期号: 11, 页码: 1459
作者:
Wang Chu
;
Zou Peng
;
Yang Caiguang
;
Liu Lei
;
Cheng Liang
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
POSTTRANSLATIONAL MODIFICATIONS
PROTEIN LIPIDATION
DNA METHYLATION
TARGET
IDENTIFICATION
GLYCOSYLATION
CHEMISTRY
HEALTH
DYRK2
P53
chemical biology
biomacromolecule
dynamic modification
modification analysis
chemical intervention
Dye-incorporated coordination polymers for direct photocatalytic trifluoromethylation of aromatics at metabolically susceptible positions
期刊论文
NATURE COMMUNICATIONS, 2018, 卷号: 9, 页码: 4024
作者:
Zhang, Tiexin
;
Guo, Xiangyang
;
Shi, Yusheng
;
He, Cheng
;
Duan, Chunying
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/02
dye
polymer
thiophene
aromatic hydrocarbon
thiophene derivative, chemical reaction
drug
dye
electron
geometry
metabolism
oxidation
polymer
redox potential, Article
arylation
chemical interaction
chemical reaction
electron transport
geometry
methylation
molecular dynamics
oxidation reduction potential
photocatalysis
radical reaction
stereoselectivity
trifluoromethylation
chemistry
halogenation
methylation, Halogenation
Hydrocarbons, Aromatic
Methylation
Thiophenes
Fabrication of Chemical Graphene Nanoribbons via Edge-Selective Covalent Modification
期刊论文
ADVANCED MATERIALS, 2015
Liao, Lei
;
Xie, Qin
;
Guo, Xuefeng
;
Liu, Zhongfan
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/03
chemical graphene nanoribbons
chemical modification
edge-selective modification
methylation
SINGLE-LAYER GRAPHENE
BILAYER GRAPHENE
CARBON NANOTUBES
STATE
DEVICES
RIBBONS
SHEETS
FORM
Toxicity and DNA methylation changes induced by perfluorooctane sulfonate (PFOS) in sea urchin Glyptocidaris crenularis (EI收录)
期刊论文
Chemosphere, 2015, 卷号: 128, 页码: 225-230
作者:
Ding, Guanghui[1]
;
Wang, Luyan[1]
;
Zhang, Jing[2]
;
Wei, Yuanyuan[2]
;
Wei, Lie[1]
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/04/25
Alkylation
Chemical reactions
DNA
Mammals
Marine biology
Methylation
Organic pollutants
Oxygen
Toxicity
Epigenetic targets and drug discovery Part 2: Histone demethylation and DNA methylation
期刊论文
Pharmacology and Therapeutics, 2015, 卷号: 151, 页码: 121-140
作者:
Liu, Ke
;
Liu, Yanli
;
Lau, Johnathan L
;
Min, Jinrong*
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/23
Histone demethylation
DNA methylation
Inhibitor
Chemical probe
Drug discovery
LSD
lysine-specific histone demethylase
HDAC
histone deacetylase
REST
REST corepressor
DNMT
DNA methyltransferase
MAO
monoamine oxidase
AML
acute myeloid leukemia
KDM
lysine-specific demethylase
MLL
mixed lineage leukemia
FAD
flavin adenine dinucleotide
PCPA
trans-2-phenylcyclopropylamine
2,4-PDCA
2, 4-pyridinedicarboxylic acid
PHD
plant homeobox domain
SCLC
small cell lung cancer
JHDMs
JmjC-domain-containing histone demethylases
NOG
N-oxalylglycine
IOX1
5-carboxy-8-hydroxyquinoline
MDS
myelodysplastic syndrome
2-OG, 2-oxoglutarate or
α-ketoglutarate
G9a
euchromatic histone-lysine N-methyltransferase 2
CoREST complex
restin corepressor complex
SAH
S-adenosyl-l-homocysteine
l
SWI complex
ATP dependent chromatin remodeling complexes
Pan-Histone Demethylase Inhibitor
the inhibitor can simultaneously inhibit both LSDs and JHDMs
LSC colony
leukemic stem cell colony
Pan JmjC domain-containing demethylase inhibitor
the inhibitor can simultaneously inhibit all the members of JHDMs
E2F1
E2F transcription factor 1
E2F2
E2F transcription factor 2
RCC
renal cell carcinoma
光电及电化学发光传感器研究环境污染物导致的DNA特异性损伤
学位论文
博士, 北京: 中国科学院研究生院, 2014
作者:
吴一萍
收藏
  |  
浏览/下载:110/0
  |  
提交时间:2015/06/25
光电化学DNA传感器
电化学发光DNA传感器
DNA化学甲基化
8-羟基脱氧鸟苷
碱基缺失
DNA糖基化
photoelectrochemical DNA snesor
electrochemiluminescence DNA sensor
DNA chemical methylation
8-oxo-7
8-dihydro-2'-deoxyguanosine
abasic sites
DNA glycosylase
Facile fabrication of Pd nanoparticle/Pichia pastoris catalysts through adsorption-reduction method: A study into effect of chemical pretreatment
期刊论文
http://dx.doi.org/10.1016/j.jcis.2014.07.038, 2014
Chen, Huimei
;
Huang, Dengpo
;
Lin, Liqin
;
Odoom-Wubah, Tareque
;
Huang, Jiale
;
Sun, Daohua
;
Li, Qingbiao,
;
黄加乐
;
孙道华
;
李清彪
;
林丽钦
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/07/22
Adsorption
Alkylation
Catalyst supports
Cells
Chemical modification
Cytology
Ions
Methylation
Nanoparticles
Palladium compounds
Yeast
Epigenetic targets and drug discovery: Part 1: Histone methylation
期刊论文
Pharmacology and Therapeutics, 2014, 卷号: 143, 期号: 3, 页码: 275-294
作者:
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/23
Epigenetics
Histone methylation
Inhibitor
Chemical probe
Cancer
PTM
posttranslational modification
HMTs
histone methyltrans-ferases
SET
Suv39, E(z) and Trithorax
SUV39
Su(var)3-9
SUV420
histone-lysine N-methyltransferase SUV420
G9a
euchromatic histone-lysine N-methyltransferase 2
GLP
G9a-like protein 1
Wiz
widely-interspaced zinc finger-containing protein
CDYL1
chromodomain Y-like protein
ACIN1
apoptotic chromatin condensation inducer in the nucleus
SAH
S-adenosyl-l-homocysteine
l
SAM
S-adenosylmethionine
Dot1
disruptor of telomeric silencing
Dot1L
DOT1-Like protein
EZH1
Enhancer of zeste homolog 1
EZH2
Enhancer of zeste homolog 2
Hox
homeotic box
PcG
Polycomb group
PRC1
Polycomb Repressive Complex 1
PRC2
Polycomb Repressive Complex 2
DZNep
3-Deazan- eplanocin A
SMYD2
SET and MYND domain-containing protein 2
PRMT
protein arginine methyltransferases
AMI-1
arginine methyltransferase inhibitor-1
MBT
Malignant Brain Tumor
PEV
position-effect variegation
HSPC
hematopoietic stem and progenitor cells
ChIP
chromatin immunoprecipitation
PK
pharmacokinetic
Photoinduced Methylation of Graphene
期刊论文
small, 2013
Liao, Lei
;
Song, Zehao
;
Zhou, Yu
;
Wang, Huan
;
Xie, Qin
;
Peng, Hailin
;
Liu, Zhongfan
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/11/10
graphene
chemical functionalization
methylation
photochemistry
SINGLE-LAYER GRAPHENE
MAGNETIC-PROPERTIES
FUNCTIONALIZATION
HYDROGENATION
COVALENT
DEVICES
FILMS
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