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期刊论文 [38]
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BRD4 inhibitor nitroxoline enhances the sensitivity of multiple myeloma cells to bortezomib in vitro and in vivo by promoting mitochondrial pathway-mediated cell apoptosis
期刊论文
THERAPEUTIC ADVANCES IN HEMATOLOGY, 2020, 卷号: 11, 页码: 12
作者:
Li, Guang
;
Zheng, Yan-Hua
;
Xu, Li
;
Feng, Juan
;
Tang, Hai-Long
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2020/12/24
apoptosis
BRD4 inhibitor
G1 phase cell cycle checkpoint
multiple myeloma
Histone deacetylase inhibitor chidamide induces growth inhibition and apoptosis in NK/T lymphoma cells through ATM-Chk2-p53-p21 signalling pathway
期刊论文
INVESTIGATIONAL NEW DRUGS, 2018, 卷号: 36, 期号: 4
作者:
Zhou, Jianan
;
Zhang, Canjing
;
Sui, Xianxian
;
Cao, Shengxuan
;
Tang, Feng
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/05
NK/T cell lymphoma
Chidamide
DNA damage response
Cell cycle checkpoint pathway
DNA methyltransferase 3a modulates chemosensitivity to gemcitabine and oxaliplatin via CHK1 and AKT in p53-deficient pancreatic cancer cells
期刊论文
MOLECULAR MEDICINE REPORTS, 2018, 卷号: Vol.17 No.1, 页码: 117-124
作者:
Jing, W
;
Song, N
;
Liu, YP
;
Qu, XJ
;
Hou, KZ
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/26
cell
cycle
checkpoint
kinase
1
DNA
methyltransferase
3a
pancreatic
ductal
adenocarcinoma
chemosensitivity
Biological function and regulation of histone and non-histone lysine methylation in response to DNA damage
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2016
Chen, Yongcan
;
Zhu, Wei-Guo
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/04
DNA damage response
lysine methylation
histone methylation
DOUBLE-STRAND BREAKS
HOMOLOGOUS RECOMBINATION REPAIR
JMJD1C DEMETHYLATES MDC1
WOLF-HIRSCHHORN SYNDROME
CHECKPOINT PROTEIN CRB2
CELL-CYCLE PROGRESSION
END-JOINING REPAIR
SACCHAROMYCES-CEREVISIAE
TUMOR-SUPPRESSOR
H3 METHYLATION
A novel role for the alcohol sensitive ring/PHD finger protein Asr1p in regulating cell cycle mediated by septin-dependent assembly in yeast
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2015, 卷号: 458, 期号: 1
作者:
Zou, Wei
;
Yan, Jinyuan
;
Zhao, Ninghui
;
Niu, Shanzhuang
;
Huang, Xiaowei
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/04
Asr1p
Septin
Cell cycle
The morphology checkpoint
Usp16 regulates kinetochore localization of Plk1 to promote proper chromosome alignment in mitosis
期刊论文
JOURNAL OF CELL BIOLOGY, 2015
Zhuo, Xiaolong
;
Guo, Xiao
;
Zhang, Xiaoyan
;
Jing, Guihua
;
Wang, Yao
;
Chen, Qiang
;
Jiang, Qing
;
Liu, Junjun
;
Zhang, Chuanmao
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2017/12/03
SPINDLE ASSEMBLY CHECKPOINT
CELL-CYCLE PROGRESSION
POLO-LIKE KINASES
MICROTUBULE ATTACHMENTS
PLK1-PBIP1 INTERACTION
PHOSPHORYLATION
POLO-LIKE-KINASE-1
DYNAMICS
PROTEIN
BUBR1
Modeling the mitotic regulatory network identifies highly efficient anti-cancer drug combinations
期刊论文
分子生物系统, 2015
Wu, Yiran
;
Zhuo, Xiaolong
;
Dai, Ziwei
;
Guo, Xiao
;
Wang, Yao
;
Zhang, Chuanmao
;
Lai, Luhua
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/10
SPINDLE-ASSEMBLY CHECKPOINT
CELL-CYCLE OSCILLATOR
AURORA-A KINASE
UBIQUITIN-CONJUGATING ENZYME
POLO-LIKE KINASES
IN-SILICO
TARGETING MITOSIS
SYSTEMS BIOLOGY
B KINASE
CANCER
Identification of DW532 as a novel anti-tumor agent targeting both kinases and tubulin
期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 7, 页码: 916-928
作者:
Peng, Ting
;
Wu, Jian-rui
;
Tong, Lin-jiang
;
Li, Meng-yuan
;
Chen, Fang
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
anti-cancer agent
hematoxylin
combretastatin
tyrosine kinase
EGFR
VEGFR
tubulin
cell cycle
spindle assembly checkpoint
anti-angiogenesis
Multiple mechanisms determine the order of APC/C substrate degradation in mitosis
期刊论文
journal of cell biology, 2014
Lu, Dan
;
Hsiao, Jennifer Y.
;
Davey, Norman E.
;
Van Voorhis, Vanessa A.
;
Foster, Scott A.
;
Tang, Chao
;
Morgan, David O.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/11
SPINDLE-ASSEMBLY CHECKPOINT
ANAPHASE-PROMOTING COMPLEX
SISTER-CHROMATID SEPARATION
SACCHAROMYCES-CEREVISIAE
BUDDING YEAST
CYCLIN-A
CELL-CYCLE
MITOTIC EXIT
DEPENDENT PROTEOLYSIS
PROTEIN-KINASE
Mechanism of chromosomal DNA replication initiation and replication fork stabilization in eukaryotes
期刊论文
science china life sciences, 2014
Wu LiHong
;
Liu Yang
;
Kong DaoChun
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2015/11/10
DNA replication origins
pre-RC assembly
replication fork stability
S phase checkpoint
ORIGIN RECOGNITION COMPLEX
CYCLIN-DEPENDENT KINASE
S-PHASE CHECKPOINT
SCHIZOSACCHAROMYCES-POMBE
FISSION YEAST
SACCHAROMYCES-CEREVISIAE
MULTIPLE MECHANISMS
FRAGILE SITES
CELL-CYCLE
BINDING
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