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Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6
作者:  Yang, Xiangbo;  Lu, Huimin;  Xie, Hang;  Zhang, Binbin;  Nie, Tianqing
收藏  |  浏览/下载:25/0  |  提交时间:2022/01/18
Structure-Based Virtual Screening and Identification of Potential Inhibitors of SARS-CoV-2 S-RBD and ACE2 Interaction 期刊论文
FRONTIERS IN CHEMISTRY, 2021, 卷号: 9, 页码: 12
作者:  Xiong, Jiacheng;  Xiang, Yusen;  Huang, Ziming;  Liu, Xiaohong;  Wang, Mengge
收藏  |  浏览/下载:43/0  |  提交时间:2021/12/01
What coronavirus 3C-like protease tells us: From structure, substrate selectivity, to inhibitor design 期刊论文
MEDICINAL RESEARCH REVIEWS, 2021, 页码: 34
作者:  Xiong, Muya;  Su, Haixia;  Zhao, Wenfeng;  Xie, Hang;  Shao, Qiang
收藏  |  浏览/下载:45/0  |  提交时间:2021/05/24
Characterization of covalent binding of tyrosine kinase inhibitors to plasma proteins 期刊论文
DRUG METABOLISM AND PHARMACOKINETICS, 2020, 卷号: 35, 期号: 5, 页码: 456-465
作者:  Liu, Xiaoyun;  Feng, Dan;  Zheng, Mingyue;  Cui, Yongmei;  Zhong, Dafang
收藏  |  浏览/下载:14/0  |  提交时间:2020/12/21
Virtual Screening for Type ⅡB Inhibitors of B-RafV600E Kinase. 期刊论文
Current computer-aided drug design, 2019
作者:  Qiu Kai-Xiong;  Zhang Wen;  Yu Fang;  Li Wei;  Sun Zhong-Wen
收藏  |  浏览/下载:31/0  |  提交时间:2019/12/04
Discovery of novel anti-angiogenesis agents. Part 10: Multi-target inhibitors of VEGFR-2, Tie-2 and EphB4 incorporated with 1,2,3-triazol. 期刊论文
European journal of medicinal chemistry, 2019, 卷号: 163, 页码: 1-9
作者:  Pan Xiaoyan;  Liang Liyuan;  Si Ru;  Wang Jin;  Zhang Qingqing
收藏  |  浏览/下载:23/0  |  提交时间:2019/11/19
Effects of histone deacetylase inhibitors on ATP-binding cassette transporters in lung cancer A549 and colorectal cancer HCT116 cells 期刊论文
ONCOLOGY LETTERS, 2019, 卷号: 18, 期号: 1, 页码: 63-71
作者:  Wang, Hao;  Chi, Chun-Hua;  Zhang, Ying;  Shi, Bin;  Jia, Ru
收藏  |  浏览/下载:25/0  |  提交时间:2019/12/11
Identification of novel and potent small-molecule inhibitors of tubulin with antitumor activities by virtual screening and biological evaluations 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 7, 页码: 659-664
作者:  Liu, Guangpu;  Jiao, Yang;  Huang, Chunxi;  Chang, Ping
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/11
Resistance mechanism of the oncogenic beta 3-alpha C deletion mutation in BRAF kinase to dabrafenib and vemurafenib revealed by molecular dynamics simulations and binding free energy calculations 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2019, 卷号: 93, 期号: 2, 页码: 177-187
作者:  Niu, Yuzhen;  Zhang, Yan;  Yao, Xiaojun
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/11
Cell-addictive dual-target traceable nanodrug for Parkinson's disease treatment via flotillins pathway 期刊论文
THERANOSTICS, 2018, 卷号: 8, 期号: 19, 页码: 5469
作者:  Li, YH;  Chen, ZX;  Lu, ZG;  Yang, QH;  Liu, LY
收藏  |  浏览/下载:46/0  |  提交时间:2018/12/29


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