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Broad targeting of triptolide to resistance and sensitization for cancer therapy 期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:  Hou, Zhen-yan;  Tong, Xiao-pei;  Peng, Yong-bo;  Zhang, Bi-Kui*;  Yan, Miao*
收藏  |  浏览/下载:50/0  |  提交时间:2019/12/03
ABC  ATP-binding cassette  AKT  V-Akt murine thymoma viral oncogene homolog  ALDH1  aldehyde dehydrogenase 1  AR  androgen receptor  Bad  Bcl-2-associated death promoter  Bak  Bcl-2 homologous antagonist killer  Bax  Bcl-2-associated X protein  Bcl-2  B-cell lymphoma  Bcl-xL  Bcl-extra large  Bcl-xs  Bcl-extra short  BCRP  breast cancer resistance protein  Bid  BH3 interacting domain death agonist  Bik  Bcl-2-interacting killer  BNIP3  Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3  CAF  cancer-associated fibroblast  CAIX  carbonic anhydrase IX  cFLIP  cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein  ChIP  chromatin immunoprecipitation  CI  Combination Index  cIAP1/2  cellular IAP1/2  CML  chronic myelogenous leukemia  CSC  cancer stem cell  DISC  death-inducing signaling complex  DR  death receptor  DRI  Dose Reduction Index  ECM  extracellular matrix  EMT  epithelial-mesenchymal transition  EpCAM  epithelial cell adhesion molecule  GLUT  glucose transporter  GSK3β  glycogen synthase kinase-3β  HIF-1  hypoxia inducible factor-1  HSF1  heat shock factor 1  HSP  heat shock protein  IAP  inhibitor of apoptosis protein  JNK  c-JUN N-terminal kinase  MAPK  mitogen-activated protein kinase  Mcl-1  myeloid leukemia cell differentiation protein  MDM2  murine double minute 2  MDR  multidrug resistance  MKP  MAPK phosphatase  MRP1  multidrug resistance protein 1  NF-κB  nuclear factor-kappaB  pAkt  phosphor-Akt  PARP  poly ADP-ribose polymerase  P-gp  P-glycoprotein  PI3K-PTEN  phosphatidylinositol 3-kinase-phosphatase and tensin homolog  PKC  phosphorylated at Ser9 by protein kinase C  pp2A  protein phosphatase 2A  REST  repressor element-1 silencing transcription factor  SAR  structure-activity relationship  TAM  tumor-associated macrophage  TFIIH  transcription factor IIH  TKI  tyrosine kinase inhibitor  TM  tumor-microenvironment  TRAIL/Apo-2L  TNF-related apoptosis-inducing ligand  tRXRα  the N-terminal truncated form of the nuclear retinoid X receptor-α  TWHF  Tripterygium wilfordii Hook F  VEGF  vascular endothelial growth factor  XIAP  X-linked IAP  XPB  xerodermapigmentosum group B protein  Triptolide  Antineoplastic  Resistance  Sensitization  Mechanism  
Autophagy: A double-edged sword in intervertebral disk degeneration 期刊论文
Clinica chimica acta, international journal of clinical chemistry, 2016, 卷号: 457, 页码: 27-35
作者:  Zhang, Shu-Jun;  Yang, Wei;  Wang, Cheng;  He, Wen-Si;  Deng, Hai-Yang
收藏  |  浏览/下载:16/0  |  提交时间:2019/12/27
IVD  intervertebral disk  NP  nucleus pulposus  AF  annulus fibrosus  CEPs  cartilaginous endplates  ECM  extracellular matrix  Col II  type II collagen  Col I  type I collagen  IDD  intervertebral disk degeneration  LBP  low back pain  miRNAs  microRNAs  ADAMTS  a disintegrin and metalloprotease with thrombospondin motif  MMP  matrix metalloproteinases  HSC70  heat shock cognate protein of 70 kDa  LAMP2A  lysosome-associated membrane protein type-2 A  Atg  autophagy-related genes  ULK  uncoordinated-51-like kinase  PI3KCIII  class III phosphatidylinositol 3-kinase  mTORC1  mammalian target of rapamycin complex 1  DFCP1  double FYVE-containing protein 1  3-MA  3-methyladenine  LC3  microtubule-associated protein 1 light chain 3  PE  phosphatidyl ethanolamine  LAMP-2  lysosomal membrane protein 2  TNF-α  tumor necrosis factor-α  IL-1β  interleukin-1β  NF-κB  nuclear factor-κB  JNK  c-Jun N-terminal kinase  SIRT1  silent mating type information regulator 2 homolog 1  TGF-β1  transforming growth factor-β1  ERK1/2  extracellular signal-regulated kinase 1/2  GRP78  glucose regulated protein 78  H2O2  hydrogen peroxide  Autophagy  IVD  IDD  NP  AF  
hCINAP negatively regulates NF-kappa B signaling by recruiting the phosphatase PP1 to deactivate IKK complex 期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2015
Qu, Linglong; Ji, Yapeng; Zhu, Xi; Zheng, Xiaofeng
收藏  |  浏览/下载:3/0  |  提交时间:2017/12/04
MicroRNAs: New players in intervertebral disc degeneration 期刊论文
Clinica Chimica Acta, 2015, 卷号: 450, 页码: 333-341
作者:  Wang, Cheng;  Wang, Wen-Jun;  Yan, Yi-Guo;  Xiang, Yong-Xiao;  Zhang, Jian
收藏  |  浏览/下载:22/0  |  提交时间:2019/12/27
IVD  intervertebral disc  NP  nucleus pulposus  AF  annulus fibrosus  CEPs  cartilaginous endplates  IDD  intervertebral disc degeneration  ECM  extracellular matrix  miRNAs  microRNAs  RNA pol  RNA polymerase  DGCR8  DiGeorge syndrome critical gene 8  Exp 5  exportin 5  TRBP  transactivating response RNA-binding protein  RISC  RNA-induced silencing complex  Ago  Argonaute  PI3K  phosphoinositide 3-kinase  MAPK  mitogen-activated protein kinase  TGF-β  transforming growth factor-β  PDGF  platelet-derived growth factor  IGF  insulin-like growth factor  EGF  epidermal growth factor  CDKI1B  cyclin-dependent kinase inhibitor 1B  TNF-α  tumor necrosis factor-α  FADD  Fas-associated death domain-containing protein  Col II  type II collagen  Col I  type I collagen  MMPs  matrix metalloproteinases  ADAMTSs  a disintegrin and metalloprotease with thrombospondin motifs  Col I  type I collagen  Col II  type II collagen  FGF2  fibroblast growth factor 2  FGFR  fibroblast growth factor receptor  IL-1β  interleukin-1β  NGF  nerve growth factor  HOXD10  homeobox D10  MiRNAs  IDD  NP cells  Apoptosis  Cell proliferation  
Apolipoprotein M 期刊论文
Clinica chimica acta, international journal of clinical chemistry, 2015, 卷号: 446, 页码: 21-29
作者:  Ren, Kun;  Tang, Zhen-Li;  Jiang, Yue;  Tan, Yan-Mei;  Yi, Guang-Hui*
收藏  |  浏览/下载:12/0  |  提交时间:2019/12/27
apo  apolipoprotein  HDL  high-density lipoprotein  HNF-1α,4α  hepatocyte nuclear factor-1α,4α  LRH-1  liver receptor homolog-1  Foxa2  forkhead box A2  PAF  platelet activating factor  LXR  liver X receptor  RXR  retinoid X receptor  FXR  farnesoid X receptor  SHP  small heterodimer partner  S1P  Sphingosine-1-Phosphate  CVD  cardiovascular disease  HDL-C  HDL cholesterol  RCT  reverse cholesterol transport  MHC  major histocompatibility complex class III  TNF  tumor necrosis factor  HRP  haptoglobin-related protein  PON-I  paraoxonase-1  SNP  single nucleotide polymorphism  T1,2D  type 1,2 diabetes  RA  rheumatoid arthritis  ABCA1  ATP-binding cassette transporter A1  PPAR-γ  peroxisome proliferator-activated receptor γ  IL  interleukin  ABCG  ATP-binding cassette sub-family G  CETP  cholesteryl ester transfer protein  SR-B1  scavenger receptor class B member 1  MODY3  maturity-onset diabetes of the young type 3  MUP  major urinary protein  RBP  retinol binding protein  RAR  retinoic acid receptor  TR  thyroid hormone receptor  PI3K  phosphatidylinositol 3-kinase  DHC  dihydrocapsaicin  HRE  hormone response element  IGF-1  insulin-like growth factors  PAF-R  platelet activating factor receptor  TGF-α,β  transforming growth factor-α,β  EGF  epidermal growth factor  HGF  hepatic growth factor  VLDL  very low-density lipoprotein  LDL  low-density lipoprotein  ldlr  LDL receptor  ldlr−/−  LDL-receptor deficient  LCAT  lecithin-cholesterol acyltransferase  CE  cholesteryl ester  TC  total cholesterol  LDL-C  LDL cholesterol  VLDL-C  VLDL cholesterol  CHD  coronary heart disease  Mets  metabolic syndrome  S1PR  S1P receptor  NF-κB  nuclear factor-κB  NO  nitrogen oxide  eNOS  endothelial nitric oxide synthase  apoM-TgN mice  mice overexpressing human apoM by approximately two-fold  apoM-TgH mice  mice overexpressing human apoM by approximately ten-fold  apoM−/− mice  apoM-null mice  apoE−/−  apoE-null mice  Apolipoprotein M  Regulation  Function  
From endosomes to the trans-Golgi network 期刊论文
http://dx.doi.org/10.1016/j.semcdb.2014.04.024, 2014
Lu, Lei; Hong, Wanjin; 洪万进
收藏  |  浏览/下载:4/0  |  提交时间:2015/07/22
Global changes of chlorophyll excitonic interactions in photosystem II during thermal denaturation 期刊论文
2010, 2010
Xu, Q; Ding, XL; Gong, YD; Kuang, TY; Zhao, NM
收藏  |  浏览/下载:3/0
Evidence for dissociation of chlorophyll b from the main light-harvesting complex in the oligomerization state isolated from marine alga, Bryopsis corticulans 期刊论文
2010, 2010
Chen, H; Shen, SH; Liang, Y; Leng, J; Tang, MJ; Gong, YD
收藏  |  浏览/下载:3/0
Effects of rewatering on light-harvesting chlorophyll a/b-protein complex of photosystem II in Zea mays 期刊论文
ACTA BOTANICA SINICA, 1999, 卷号: 41, 期号: 6, 页码: 613-616
作者:  Hao, LM;  Wang, HL;  Liang, HG
收藏  |  浏览/下载:6/0  |  提交时间:2015/12/14
Two-dimensional crystallization and preliminary structure analysis of lhc-ii from cucumber and spinach 期刊论文
Science in china series c-life sciences, 1998, 卷号: 41, 期号: 3, 页码: 265-271
作者:  Xu, W;  Zhang, X;  Lou, SQ;  Wang, KB;  Huang, YG
收藏  |  浏览/下载:47/0  |  提交时间:2019/05/09


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