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Design, synthesis, in vitro evaluation of a new pyrrolo[1,2-a]thiazolo[5,4-d]pyrimidinone derivatives as cholinesterase inhibitors against Alzheimer's disease
期刊论文
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2022, 卷号: 59, 期号: 6, 页码: 1086-1101
作者:
Zeng, Y (Zeng, Yan) [1] , [2]
;
Nie, LF (Nie, Lifei) [1]
;
Liu, L (Liu, Liu) [1]
;
Niu, C (Niu, Chao) [1] , [2]
;
Li, Y (Li, Yi) [1] , [2]
收藏
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浏览/下载:26/0
  |  
提交时间:2022/06/21
Calibration of the air shower energy scale of the water and air Cherenkov techniques in the LHAASO experiment
期刊论文
PHYSICAL REVIEW D, 2021, 卷号: 104, 期号: 6
作者:
Aharonian, F.
;
An, Q.
;
Axikegu
;
Bai, L. X.
;
Bai, Y. X.
收藏
  |  
浏览/下载:130/0
  |  
提交时间:2021/10/08
Ultrahigh-energy photons up to 1.4 petaelectronvolts from 12 γ-ray Galactic sources
期刊论文
Nature, 2021, 卷号: 594, 期号: 7861, 页码: 33-36
作者:
Cao, Zhen
;
Aharonian, F. A.
;
An, Q.
;
Axikegu
;
Bai, L. X.
收藏
  |  
浏览/下载:171/0
  |  
提交时间:2021/07/17
MeSHHeading2vec: a new method for representing MeSH headings as vectors based on graph embedding algorithm
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 2, 页码: 2085-2095
作者:
Guo,ZH (Guo, Zhen-Hao) 1
;
You,ZH (You,Zhu-Hong) 1, 2
;
Huang,DS (Huang, De-Shuang) 3, 4
;
Yi, HC (Yi, Hai-Cheng) 2
;
Zheng, K (Zheng, Kai) 5
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浏览/下载:147/0
  |  
提交时间:2021/08/09
MeSHHeading2vecMeSH relationship networkgraph embeddingcomputational prediction model
A deep learning-based method for drug-target interaction prediction based on long short-term memory neural network
期刊论文
BMC MEDICAL INFORMATICS AND DECISION MAKING, 2020, 卷号: 20, 期号: 1, 页码: 1-9
作者:
Wang, YB (Wang, Yan-Bin)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 1 ]
;
Yang, S (Yang, Shan)[ 1 ]
;
Yi, HC (Yi, Hai-Cheng)[ 1,2 ]
;
Chen, ZH (Chen, Zhan-Heng)[ 1,2 ]
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/04/21
Drug-target
Deep learning
Legendre moment
Long short-term memory
A learning based framework for diverse biomolecule relationship prediction in molecular association network
期刊论文
COMMUNICATIONS BIOLOGY, 2020, 卷号: 3, 期号: 1, 页码: 1-9
作者:
Guo, ZH (Guo, Zhen-Hao)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 1,2 ]
;
Huang, DS (Huang, De-Shuang)[ 3 ]
;
Yi, HC (Yi, Hai-Cheng)[ 1,2 ]
;
Chen, ZH (Chen, Zhan-Heng)[ 1,2 ]
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/04/21
RPI-SE: a stacking ensemble learning framework for ncRNA-protein interactions prediction using sequence information
期刊论文
BMC BIOINFORMATICS, 2020, 卷号: 21, 期号: 1, 页码: 1-10
作者:
Yi, HC (Yi, Hai-Cheng)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 1,2 ]
;
Wang, MN (Wang, Mei-Neng)[ 3 ]
;
Guo, ZH (Guo, Zhen-Hao)[ 1 ]
;
Wang, YB (Wang, Yan-Bin)[ 1 ]
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/04/21
Sequence analysis
RNA-protein interaction
ncRNA
Ensemble learning
Position weight matrix
Legendre moments
Prediction of Drug-Target Interactions From Multi-Molecular Network Based on Deep Walk Embedding Model
期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2020, 卷号: 8, 期号: 6, 页码: 1-9
作者:
Chen, ZH (Chen, Zhan-Heng)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 1,2 ]
;
Guo, ZH (Guo, Zhen-Hao)[ 1,2 ]
;
Yi, HC (Yi, Hai-Cheng)[ 1,2 ]
;
Luo, GX (Luo, Gong-Xu)[ 1,2 ]
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/09/09
drug-target interactions
molecular association network
attribute feature
behavior feature
random forest
Bioentity2vec: Attribute- and behavior-driven representation for predicting multi-type relationships between bioentities
期刊论文
GIGASCIENCE, 2020, 卷号: 9, 期号: 6, 页码: 1-12
作者:
Guo, ZH (Guo, Zhen-Hao)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 1,2 ]
;
Wang, YB (Wang, Yan-Bin)[ 3 ]
;
Huang, DS (Huang, De-Shuang)[ 4 ]
;
Yi, HC (Yi, Hai-Cheng)[ 1,2 ]
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/11/04
network biology
system biology
Bioentity2vec
multi-type relationship prediction
Prediction of Self-Interacting Proteins from Protein Sequence Information Based on Random Projection Model and Fast Fourier Transform
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 卷号: 20, 期号: 4, 页码: 1-15
作者:
Chen, ZH (Chen, Zhan-Heng)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 1,2 ]
;
Li, LP (Li, Li-Ping)[ 1 ]
;
Wang, YB (Wang, Yan-Bin)[ 1 ]
;
Wong, L (Wong, Leon)[ 1,2 ]
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2019/05/16
self-interacting proteins
position-specific scoring matrix
fast Fourier transform
random projection
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