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科研机构
上海药物研究所 [5]
深圳先进技术研究院 [2]
南华大学 [1]
厦门大学 [1]
暨南大学 [1]
复旦大学上海医学院 [1]
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内容类型
期刊论文 [10]
会议论文 [1]
发表日期
2018 [1]
2016 [2]
2015 [4]
2014 [3]
2010 [1]
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Small Heterodimer Partner Regulates Circadian Cytochromes p450 and Drug-Induced Hepatotoxicity
期刊论文
2018, 卷号: 8, 期号: 19, 页码: 5246
作者:
Zhang, Tianpeng[1,2,3]
;
Yu, Fangjun[1]
;
Guo, Lianxia[1]
;
Chen, Min[1]
;
Yuan, Xue[1]
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/17
Structures and regulation of non-X orphan nuclear receptors: A retinoid hypothesis
期刊论文
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2016, 卷号: 157, 页码: 27-40
作者:
Zhi, Xiaoyong
;
Zhou, X. Edward
;
Melcher, Karsten
;
Xu, H. Eric
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Orphan nuclear receptor
Ligand
Crystal structure
Gene repression
Activation of farnesoid X receptor promotes triglycerides lowering by suppressing phospholipase A2 G12B expression
期刊论文
Molecular and Cellular Endocrinology, 2016
作者:
Qingli Liu
;
Meng Yang
;
Xuekun Fu
;
Renzhong Liu
;
Caijun Sun
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2017/01/16
Structural Basis for Small Molecule NDB (N-Benzyl-N-(3-(tert-butyl)-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino) Benzamide) as a Selective Antagonist of Farnesoid X Receptor alpha (FXR alpha) in Stabilizing the Homodimerization of the Receptor
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2015, 卷号: 290, 期号: 32, 页码: 19888-19899
作者:
Xu, Xing
;
Xu, Xin
;
Liu, Peng
;
Zhu, Zhi-yuan
;
Chen, Jing
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
Structural basis for corepressor assembly by the orphan nuclear receptor TLX
期刊论文
GENES & DEVELOPMENT, 2015, 卷号: 29, 期号: 4, 页码: 440-450
作者:
Zhi, Xiaoyong
;
Zhou, X. Edward
;
He, Yuanzheng
;
Searose-Xu, Kelvin
;
Zhang, Chun-Li
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
COUP
PNR
SHP
TLX
Activation of the farnesoid X receptor promotes triglyceride lowering by suppressingPhospholipase A2 G12B expression in hyperlipidemic mice
会议论文
Keystone Symposia Conference- The Crossroads of Lipid Metabolism and Diabetes, 丹麦哥本哈根
作者:
Qingli Liu
;
Meng Yang
;
Renzhong Liu
;
Yang Lei
;
Xuekun Fu
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2016/01/27
Apolipoprotein M
期刊论文
Clinica chimica acta, international journal of clinical chemistry, 2015, 卷号: 446, 页码: 21-29
作者:
Ren, Kun
;
Tang, Zhen-Li
;
Jiang, Yue
;
Tan, Yan-Mei
;
Yi, Guang-Hui*
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/27
apo
apolipoprotein
HDL
high-density lipoprotein
HNF-1α,4α
hepatocyte nuclear factor-1α,4α
LRH-1
liver receptor homolog-1
Foxa2
forkhead box A2
PAF
platelet activating factor
LXR
liver X receptor
RXR
retinoid X receptor
FXR
farnesoid X receptor
SHP
small heterodimer partner
S1P
Sphingosine-1-Phosphate
CVD
cardiovascular disease
HDL-C
HDL cholesterol
RCT
reverse cholesterol transport
MHC
major histocompatibility complex class III
TNF
tumor necrosis factor
HRP
haptoglobin-related protein
PON-I
paraoxonase-1
SNP
single nucleotide polymorphism
T1,2D
type 1,2 diabetes
RA
rheumatoid arthritis
ABCA1
ATP-binding cassette transporter A1
PPAR-γ
peroxisome proliferator-activated receptor γ
IL
interleukin
ABCG
ATP-binding cassette sub-family G
CETP
cholesteryl ester transfer protein
SR-B1
scavenger receptor class B member 1
MODY3
maturity-onset diabetes of the young type 3
MUP
major urinary protein
RBP
retinol binding protein
RAR
retinoic acid receptor
TR
thyroid hormone receptor
PI3K
phosphatidylinositol 3-kinase
DHC
dihydrocapsaicin
HRE
hormone response element
IGF-1
insulin-like growth factors
PAF-R
platelet activating factor receptor
TGF-α,β
transforming growth factor-α,β
EGF
epidermal growth factor
HGF
hepatic growth factor
VLDL
very low-density lipoprotein
LDL
low-density lipoprotein
ldlr
LDL receptor
ldlr−/−
LDL-receptor deficient
LCAT
lecithin-cholesterol acyltransferase
CE
cholesteryl ester
TC
total cholesterol
LDL-C
LDL cholesterol
VLDL-C
VLDL cholesterol
CHD
coronary heart disease
Mets
metabolic syndrome
S1PR
S1P receptor
NF-κB
nuclear factor-κB
NO
nitrogen oxide
eNOS
endothelial nitric oxide synthase
apoM-TgN mice
mice overexpressing human apoM by approximately two-fold
apoM-TgH mice
mice overexpressing human apoM by approximately ten-fold
apoM−/− mice
apoM-null mice
apoE−/−
apoE-null mice
Apolipoprotein M
Regulation
Function
Cytoplasmic Tyrosine Phosphatase Shp2 Coordinates Hepatic Regulation of Bile Acid and FGF15/19 Signaling to Repress Bile Acid Synthesis
期刊论文
CELL METABOLISM, 2014, 卷号: 20, 期号: 2, 页码: 320-332
作者:
Li, Shuangwei
;
Hsu, Diane D. F.
;
Li, Bing
;
Luo, Xiaolin
;
Alderson, Nazilla
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Structural insights into gene repression by the orphan nuclear receptor SHP
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 卷号: 111, 期号: 2, 页码: 839-844
作者:
Zhi, Xiaoyong
;
Zhou, X. Edward
;
He, Yuanzheng
;
Zechner, Christoph
;
Suino-Powell, Kelly M.
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Targeting Nuclear Receptors with Marine Natural Products
期刊论文
http://dx.doi.org/10.3390/md12020601, 2014
Yang, Chunyan
;
Li, Qianrong
;
Li, Yong
;
杨春燕
;
李勇
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/07/22
PREGNANE-X-RECEPTOR
RETINOIC ACID RECEPTORS
OXYGEN CHANNELING IMMUNOASSAY
SPONGE THEONELLA-SWINHOEI
LIGAND-BINDING DOMAINS
INDEPENDENT TRANSCRIPTIONAL ACTIVATION
CONSTITUTIVE ANDROSTANE RECEPTOR
SMALL HETERODIMER PARTNER
LIPOPROTEIN-LIPASE GENE
STEROIDOGENIC FACTOR-I
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