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Small Heterodimer Partner Regulates Circadian Cytochromes p450 and Drug-Induced Hepatotoxicity 期刊论文
2018, 卷号: 8, 期号: 19, 页码: 5246
作者:  Zhang, Tianpeng[1,2,3];  Yu, Fangjun[1];  Guo, Lianxia[1];  Chen, Min[1];  Yuan, Xue[1]
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/17
Structures and regulation of non-X orphan nuclear receptors: A retinoid hypothesis 期刊论文
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2016, 卷号: 157, 页码: 27-40
作者:  Zhi, Xiaoyong;  Zhou, X. Edward;  Melcher, Karsten;  Xu, H. Eric
收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08
Activation of farnesoid X receptor promotes triglycerides lowering by suppressing phospholipase A2 G12B expression 期刊论文
Molecular and Cellular Endocrinology, 2016
作者:  Qingli Liu;  Meng Yang;  Xuekun Fu;  Renzhong Liu;  Caijun Sun
收藏  |  浏览/下载:10/0  |  提交时间:2017/01/16
Structural Basis for Small Molecule NDB (N-Benzyl-N-(3-(tert-butyl)-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino) Benzamide) as a Selective Antagonist of Farnesoid X Receptor alpha (FXR alpha) in Stabilizing the Homodimerization of the Receptor 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2015, 卷号: 290, 期号: 32, 页码: 19888-19899
作者:  Xu, Xing;  Xu, Xin;  Liu, Peng;  Zhu, Zhi-yuan;  Chen, Jing
收藏  |  浏览/下载:10/0  |  提交时间:2019/01/08
Structural basis for corepressor assembly by the orphan nuclear receptor TLX 期刊论文
GENES & DEVELOPMENT, 2015, 卷号: 29, 期号: 4, 页码: 440-450
作者:  Zhi, Xiaoyong;  Zhou, X. Edward;  He, Yuanzheng;  Searose-Xu, Kelvin;  Zhang, Chun-Li
收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08
COUP  PNR  SHP  TLX  
Activation of the farnesoid X receptor promotes triglyceride lowering by suppressingPhospholipase A2 G12B expression in hyperlipidemic mice 会议论文
Keystone Symposia Conference- The Crossroads of Lipid Metabolism and Diabetes, 丹麦哥本哈根
作者:  Qingli Liu;  Meng Yang;  Renzhong Liu;  Yang Lei;  Xuekun Fu
收藏  |  浏览/下载:25/0  |  提交时间:2016/01/27
Apolipoprotein M 期刊论文
Clinica chimica acta, international journal of clinical chemistry, 2015, 卷号: 446, 页码: 21-29
作者:  Ren, Kun;  Tang, Zhen-Li;  Jiang, Yue;  Tan, Yan-Mei;  Yi, Guang-Hui*
收藏  |  浏览/下载:12/0  |  提交时间:2019/12/27
apo  apolipoprotein  HDL  high-density lipoprotein  HNF-1α,4α  hepatocyte nuclear factor-1α,4α  LRH-1  liver receptor homolog-1  Foxa2  forkhead box A2  PAF  platelet activating factor  LXR  liver X receptor  RXR  retinoid X receptor  FXR  farnesoid X receptor  SHP  small heterodimer partner  S1P  Sphingosine-1-Phosphate  CVD  cardiovascular disease  HDL-C  HDL cholesterol  RCT  reverse cholesterol transport  MHC  major histocompatibility complex class III  TNF  tumor necrosis factor  HRP  haptoglobin-related protein  PON-I  paraoxonase-1  SNP  single nucleotide polymorphism  T1,2D  type 1,2 diabetes  RA  rheumatoid arthritis  ABCA1  ATP-binding cassette transporter A1  PPAR-γ  peroxisome proliferator-activated receptor γ  IL  interleukin  ABCG  ATP-binding cassette sub-family G  CETP  cholesteryl ester transfer protein  SR-B1  scavenger receptor class B member 1  MODY3  maturity-onset diabetes of the young type 3  MUP  major urinary protein  RBP  retinol binding protein  RAR  retinoic acid receptor  TR  thyroid hormone receptor  PI3K  phosphatidylinositol 3-kinase  DHC  dihydrocapsaicin  HRE  hormone response element  IGF-1  insulin-like growth factors  PAF-R  platelet activating factor receptor  TGF-α,β  transforming growth factor-α,β  EGF  epidermal growth factor  HGF  hepatic growth factor  VLDL  very low-density lipoprotein  LDL  low-density lipoprotein  ldlr  LDL receptor  ldlr−/−  LDL-receptor deficient  LCAT  lecithin-cholesterol acyltransferase  CE  cholesteryl ester  TC  total cholesterol  LDL-C  LDL cholesterol  VLDL-C  VLDL cholesterol  CHD  coronary heart disease  Mets  metabolic syndrome  S1PR  S1P receptor  NF-κB  nuclear factor-κB  NO  nitrogen oxide  eNOS  endothelial nitric oxide synthase  apoM-TgN mice  mice overexpressing human apoM by approximately two-fold  apoM-TgH mice  mice overexpressing human apoM by approximately ten-fold  apoM−/− mice  apoM-null mice  apoE−/−  apoE-null mice  Apolipoprotein M  Regulation  Function  
Cytoplasmic Tyrosine Phosphatase Shp2 Coordinates Hepatic Regulation of Bile Acid and FGF15/19 Signaling to Repress Bile Acid Synthesis 期刊论文
CELL METABOLISM, 2014, 卷号: 20, 期号: 2, 页码: 320-332
作者:  Li, Shuangwei;  Hsu, Diane D. F.;  Li, Bing;  Luo, Xiaolin;  Alderson, Nazilla
收藏  |  浏览/下载:21/0  |  提交时间:2019/01/08
Structural insights into gene repression by the orphan nuclear receptor SHP 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 卷号: 111, 期号: 2, 页码: 839-844
作者:  Zhi, Xiaoyong;  Zhou, X. Edward;  He, Yuanzheng;  Zechner, Christoph;  Suino-Powell, Kelly M.
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
Targeting Nuclear Receptors with Marine Natural Products 期刊论文
http://dx.doi.org/10.3390/md12020601, 2014
Yang, Chunyan; Li, Qianrong; Li, Yong; 杨春燕; 李勇
收藏  |  浏览/下载:3/0  |  提交时间:2015/07/22


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