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Loratadine oral bioavailability enhancement via solid dispersion loaded oro-dispersible films: Formulation, characterization and pharmacokinetics
期刊论文
COLLOIDS AND SURFACES B-BIOINTERFACES, 2023, 卷号: 230
作者:
Islam, Nayyer
;
Khan, Naveed Ullah
;
Razzaq, Anam
;
Menaa, Farid
;
Khan, Zaheer Ullah
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/11/17
Loratadine
Solid dispersion
Oro-dispersible film
Bioavailability
Urticaria
Population Pharmacokinetics of Tacrolimus in Pediatric Patients With Umbilical Cord Blood Transplant
期刊论文
JOURNAL OF CLINICAL PHARMACOLOGY, 2022
作者:
Zuo, Meiling
;
Shang, Yue
;
Guo, Ye
;
Sun, Yuxuan
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  |  
浏览/下载:16/0
  |  
提交时间:2022/12/23
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
Tolerability, Pharmacokinetic, and Pharmacodynamic Profiles of Henagliflozin, a Novel Selective Inhibitor of Sodium-Glucose Cotransporter 2, in Healthy Subjects Following Single- and Multiple-dose Administration
期刊论文
CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 2, 页码: 396-409
作者:
Zhang, Yi-fan
;
Liu, Yan-mei
;
Yu, Chen
;
Wang, Ya-ting
;
Zhan, Yan
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2021/05/24
diabetes
henagliflozin
pharmacodynamics
pharmacokinetics
SGLT-2 inhibitors
Characterization and quantitative determination of henagliflozin metabolites in humans
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 192, 页码: 8
作者:
Chen, Zhendong
;
Li, Liang
;
Zhan, Yan
;
Zhang, Yifan
;
Liu, Haiyan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
Henagliflozin
Metabolism
LC-MS/MS
Pharmacokinetics, mass balance, and metabolism of [C-14]vicagrel, a novel irreversible P2Y(12) inhibitor in humans
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Zheng, Yuan-dong
;
Zhang, Hua
;
Zhan, Yan
;
Bian, Yi-cong
;
Ma, Sheng
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/05/24
vicagrel
[C-14]vicagrel
vicagrel pharmacokinetics
vicagrel metabolism
mass balance
P2Y(12) receptor inhibitor
Assessment of micafungin loading dosage regimens against Candida spp. in ICU patients by Monte Carlo simulations
期刊论文
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2020
作者:
Lu, Xiaoqing
;
Xu, Gaoqi
;
Chen, Lu
;
Fan, Jingjing
;
Li, Mengxue
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/11/26
Micafungin
Loading dose
Candida spp
ICU patients
The Nonclinical Pharmacokinetics and Prediction of Human Pharmacokinetics of SPH3127, a Novel Direct Renin Inhibitor
期刊论文
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2020, 卷号: 45, 期号: 1, 页码: 15-26
作者:
Zhang, Leduo
;
Mao, Yu
;
Gao, Zhiwei
;
Chen, Xiaoyan
;
Li, Xin
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
Thermostability detection and optimization of glycoengineered antibodies and antibody-drug conjugates based on differential scanning flouremitry analysis
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 94, 页码: 10
作者:
Qin, Ken
;
Shi, Wei
;
Zhao, Lei
;
Li, Mingjie
;
Tang, Yubo
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2020/07/01
DSF
Thermostability
Glycosylation
Glyco-engineered antibodies
ADCs
New linker structures applied in glycosite-specific antibody drug conjugates
期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 17, 页码: 3144-3149
作者:
Faridoon
;
Shi, Wei
;
Qin, Ken
;
Tang, Yubo
;
Li, Mingjie
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
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