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兰州大学 [1]
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武汉大学 [1]
复旦大学上海医学院 [1]
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期刊论文 [7]
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Boehmenan, a Lignan From the Chinese Medicinal Plant Clematis armandii, Inhibits A431 Cell Growth via Blocking p70S6/S6 Kinase Pathway
期刊论文
INTEGRATIVE CANCER THERAPIES, 2017, 卷号: 16, 期号: 3
作者:
Pan, Li-Long
;
Wang, Xi-Ling
;
Luo, Xiao-Ling
;
Liu, Si-Yu
;
Xu, Peng
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
boehmenan
A431
proliferation
cell cycle
p70 ribosomal protein S6 kinase
Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells
期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:
Yang, Xin
;
Xu, Zhipeng
;
Zhang, Chunlan
;
Cai, Zixin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/12/03
A1c
glycated hemoglobin
AACE
American Association of Clinical Endocrinologists
ACC
acetyl-CoA carboxylase
ADA
American Diabetes Association
Akt/PKB
tyrosine kinase/protein kinase B
AMP
adenosine monophosphate
AMPK
adenosine monophosphate-activated protein
Ang II
angiotensin II
ATP
adenosine triphosphate
BAT
brown adipose tissue
CHOP
CEBP-homologous protein
CEBP
CCAAT enhancer binding protein
CoA
coenzyme A
DPP
Diabetes Prevention Program
EASD
European Association for the Study of Diabetes
eNOS
endothelial nitric oxide synthase
ER
endoplasmic reticulum
FDA
Food and Drug Administration
FFA
free fatty acid
FOXO1
forkhead box protein O1
G6P
glucose 6-phosphate
GDM
gestational diabetes mellitus
GIPR
glucose-dependent insulinotropic polypeptide receptor
GLP-1R
glucagon-like peptide-1 receptor
GLUT1
glucose transporter-1
GLUT4
glucose transporter type 4
GLUTs
glucose transporters
G6P
glucose 6-phosphate, glucose transporter-1
GPR40
G protein-coupled receptor 40
HbA1c
hemoglobin A1c
HGP
hepatic glucose production
HSL
hormone sensitive lipase
IL-6
interleukin 6
INS-1
insulinoma cells in rat
IR
insulin resistance
IRS-1
insulin receptor substrate 1
JNK
c-Jun. N-terminal kinase
Kir6.2
inwardly rectifying potassium/kalium channel
LDs
lipid droplets
LDL
low density lipoprotein
LV
left ventricular
MIN6 cells
mouse insulinoma cells
MAPK
mitogen-activated protein kinases
mPTP
mitochondrial permeability transition pore opening
mTOR
mammalian target of rapamycin
NADPH
nicotinamide adenine dinucleotide phosphate
NF-kappaB
nuclear factors-kappa B
NIT-1 cells
insulinoma cells
p70S6K
p70 ribosomal S6 kinase
PA
palmitic acid
NOS
NADPH oxidase
p38 MAPK
p38 mitogen-activated protein kinase
PA
palmitic acid
PCOS
polycystic ovary syndrome
PGC-1α
peroxisome proliferator-activated receptor-g coactivator-1α
PI3K
phosphatidylinositol 3-kinase
PKB
protein kinase B
PKC
protein kinase C
PPARα
peroxisome-proliferator activated receptor α
PTP
permeability transition pore
RCT
randomized controlled trial
RISK
reperfusion injury salvage kinase
ROS
reactive oxygen species
SERCA2
reticulum sarcoplasmic Ca2 +-ATPase
RISK
reperfusion injury salvage kinase
Smad3
mothers against decapentaplegic homolog 3
SRC-2
steroid receptor coactivator 2
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TGFβ1
transforming growth factor β1
TLR4
Toll-like receptor
TNF-α
tumor necrosis factor α
TR4
testicular receptor 4
UKPDS
United Kingdom Prospective Diabetes Study
VLDL
very low density lipoprotein
Metformin
Pancreatic β Cells
Heart failure
Insulin sensitizer
The synergistic inhibition of breast cancer proliferation by combined treatment with 4EGI-1 and MK2206
期刊论文
2015, 卷号: 14, 期号: 2, 页码: 232-242
作者:
Wang, Hongtao
;
Huang, Fang
;
Wang, Jian
;
Wang, Peng
;
Lv, Wenjie
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/13
AKT
eIF4E
eIF4F complex
cap-dependent translation
4EBP1
4EGI-1
mTORC1
mTORC2
eIF4E
eukaryotic translation initiation factor 4E
4EBP1
eIF4E-binding protein 1
p70S6K
ribosomal p70 S6 kinase
mTORC1
mammalian target of rapamycin complex 1
mTORC2 mammalian target of rapamycin complex 2
PI3K
phosphatidylinositol 3-kinase
ER stress
endoplasmic reticulum stress
Activation of mammalian target of rapamycin contributes to pain nociception induced in rats by BmK I, a sodium channel-specific modulator
期刊论文
NEUROSCIENCE BULLETIN, 2014, 卷号: 30, 页码: 21-32
作者:
Jiang, Feng[1]
;
Hua, Li-Ming[2]
;
Jiao, Yun-Lu[3]
;
Ye, Pin[4]
;
Fu, Jin[5]
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/04/30
BmK I
mTOR
p70 ribosomal S6 protein kinase
4E-binding protein 1
pain
dorsal root ganglion
ATP-MEDIATED PROTEIN KINASE B Akt/MAMMALIAN TARGET OF RAPAMYCIN mTOR/P70 RIBOSOMAL S6 PROTEIN p70S6 KINASE SIGNALING PATHWAY ACTIVATION PROMOTES IMPROVEMENT OF LOCOMOTOR FUNCTION AFTER SPINAL CORD INJURY IN RATS
期刊论文
NEUROSCIENCE, 2010, 卷号: 169, 期号: 3, 页码: 1046-1062
作者:
Hu, LY
;
Sun, ZG
;
Wen, YM
;
Cheng, GZ
;
Wang, SL
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2016/03/29
mTOR
rapamycin
signal transduction pathway
locomotor functional recovery
spine
nervous system injury
Palmitate Induced Insulin Resistance by PKCtheta-Dependent Activation of mTOR/S6K Pathway in C2C12 Myotubes
期刊论文
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, 2010, 卷号: 118, 期号: 9
作者:
Wang, X.
;
Yu, W.
;
Nawaz, A.
;
Guan, F.
;
Sun, S.
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
PKC theta
mammalian target of rapamycin (mTOR)
p70 ribosomal S6 kinase (S6K)
insulin resistance
palmitic acid
MEK1-independent activation of MAPK and MEK1-dependent activation of p70 S6 kinase by stem cell factor (SCF) in ovarian cancer cells.
期刊论文
Biochemical and Biophysical Research Communications, 2009, 卷号: 382, 期号: 2, 页码: 385-389
作者:
Liu L
;
Du C
;
Zhang X
;
Hou N
;
Zhao D
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/26
Cell Line
Tumor
Cell Proliferation
Enzyme Activation
Female
Gene Knockdown Techniques
Humans
MAP Kinase Kinase 1
Mitogen-Activated Protein Kinase Kinases
Ovarian Neoplasms
RNA Interference
Ribosomal Protein S6 Kinases
70-kDa
Stem Cell Factor
*酶激活
卵巢肿瘤
干细胞因子
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