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清华大学 [11]
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期刊论文 [72]
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Significant Inhibition of Porcine Epidemic Diarrhea Virus In Vitro by Remdesivir, Its Parent Nucleoside and beta-d-N-4-hydroxycytidine
期刊论文
VIROLOGICA SINICA, 2021, 页码: 9
作者:
Xie, Yuanchao
;
Guo, Xiaozhen
;
Hu, Tianwen
;
Wei, Daibao
;
Ma, Xiuli
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/05/24
Porcine epidemic diarrhea virus (PEDV)
Nucleoside analog
RNA dependent RNA polymerase (RdRp)
Antiviral activity
Potency and pharmacokinetics of GS-441524 derivatives against SARS-CoV-2
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 46, 期号: 9, 页码: 1-12
作者:
Wei, DB (Wei, Daibao)
;
Hu, TW (Hu, Tianwen)
;
Zhang, YM (Zhang, Yumin)
;
Zheng, W (Zheng, Wei)
;
Xue, HT (Xue, Haitao)
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  |  
浏览/下载:28/0
  |  
提交时间:2021/10/14
Covid-19
SARS-CoV-2
GS-441524
Antiviral
Nucleoside
Prodrug
Isobutyrate
Effects of traditional Chinese medicine formula Le-Cao-Shi on hepatitis B: In vivo and in vitro studies
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 244, 页码: 10
作者:
Zhao, Qing
;
Ren, Xia
;
Chen, Min
;
Yue, Shi-Jun
;
Zhang, Meng-Qi
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  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
Traditional Chinese medicine
Formula Le-Cao-Shi
Hepatitis B virus
Anti-Hepatitis B
Discovery of pyrimidine nucleoside dual prodrugs and pyrazine nucleosides as novel anti-HCV agents
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 5, 页码: 748-759
作者:
Guo, Shuang
;
Xu, Mingshuo
;
Guo, Qi
;
Zhu, Fuqiang
;
Jiang, Xiangrui
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  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
Nucleoside
Double prodrug
Phosphoramidate
Anti-HCV
Pyrazine
Characterization of MtdV as a chorismate lyase essential to A201A biosynthesis and precursor-directed biosynthesis of new analogs
期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2019, 卷号: 17, 期号: 15, 页码: 3760, 3764
作者:
Ju, Jianhua
;
Li, Qinglian
;
Huang, Hongbo
;
Song, Yongxiang
;
Zhu, Qinghua
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  |  
浏览/下载:41/0
  |  
提交时间:2019/09/09
Efficacy of Nucleoside Analogs for Chronic Hepatitis B Virus-Related Hepatocellular Carcinoma After Curative Treatment: A Meta-Analysis
期刊论文
DIGESTIVE DISEASES AND SCIENCES, 2018, 卷号: 63, 期号: 12
作者:
Zhang, Guangcong
;
Yu, Xiangnan
;
Liu, Peng
;
Huang, Xiaoxi
;
Jiang, Xuemei
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  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
Nucleoside analog
Hepatocellular carcinoma
Curative treatment
Meta-analysis
Performance of serum HBcrAg in chronic hepatitis B patients with 8-year nucleoside analogs therapy.
期刊论文
Clinics and research in hepatology and gastroenterology, 2018
作者:
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浏览/下载:7/0
  |  
提交时间:2019/02/25
Hepatitis
B
Kinetics
Nucleos(t)ide
analogs
therapy
Serum
hepatitis
B
core-related
antigen
Preparation of 5 '-deoxy-5 '-amino-5 '-C-methyl adenosine derivatives and their activity against DOT1L
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 22, 页码: 4960-4963
作者:
Liu, Tongchao
;
Xie, Wuchen
;
Li, Cong
;
Ren, Huanming
;
Mao, Yudong
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  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
5'-Deoxy-5'-amino-5'-C-methyl adenosine derivative
N-glycosylation
Nucleoside synthesis
DOT1L inhibitor
Structure activity relationship
Nucleoside-linked shunt products in the reaction catalyzed by the class C radical S-adenosylmethionine methyltransferase NosN
期刊论文
CHEMICAL COMMUNICATIONS, 2017, 卷号: 53, 期号: 37, 页码: 5235-5238
作者:
Ding, Wei
;
Wu, Yujie
;
Ji, Xinjian
;
Qianzhu, Haocheng
;
Chen, Fener
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  |  
浏览/下载:30/0
  |  
提交时间:2019/10/09
The Ca2+/CaMKK2 axis mediates the telbivudine induced upregulation of creatine kinase: Implications for mechanism of antiviral nucleoside analogs' side effect
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2017, 卷号: 146
作者:
Long Jianfei
;
Wang Min
;
Ma Chunlai
;
Chen Bicui
;
Zhang Jiming
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  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Telbivudine (LdT)
Creatine kinase (CK)
Ca2+/CaMKK2 axis
CaMKK2/AMPK
Oxidative stress
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