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Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:  Xiao, Li;  Wang, Yujun;  Zhang, Mumei;  Wu, Weiwei;  Kong, Linghui
收藏  |  浏览/下载:93/0  |  提交时间:2020/07/01
Pharmacological Characterization of Dezocine, a Potent Analgesic Acting as a kappa Partial Agonist and mu Partial Agonist 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8
作者:  Wang, Yu-Hua;  Chai, Jing-Rui;  Xu, Xue-Jun;  Ye, Ru-Feng;  Zan, Gui-Ying
收藏  |  浏览/下载:94/0  |  提交时间:2019/01/08
The Pharmacological Heterogeneity of Nepenthone Analogs in Conferring Highly Selective and Potent kappa-Opioid Agonistic Activities 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2017, 卷号: 8, 期号: 4, 页码: 766-776
作者:  Li, Wei;  Long, Jian-Dong;  Qian, Yuan-Yuan;  Long, Yu;  Xu, Xue-Jun
收藏  |  浏览/下载:34/0  |  提交时间:2019/01/08
Novel kappa-opioid receptor agonist MB-1C-OH produces potent analgesia with less depression and sedation 期刊论文
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 5, 页码: 565-571
作者:  Zhang, Le-sha;  Wang, Jun;  Chen, Jian-chun;  Tao, Yi-min;  Wang, Yu-hua
收藏  |  浏览/下载:20/0  |  提交时间:2019/01/08
Adenosine A(1) receptor agonist N-6-cyclohexyladenosine induced phosphorylation of delta oploid receptor and desensitization of its signaling opioid 期刊论文
ACTA PHARMACOLOGICA SINICA, 2010, 卷号: 31, 期号: 7, 页码: 784-790
作者:  Cheng, Yun;  Tao, Yi-min;  Sun, Jian-feng;  Wang, Yu-hua;  Xu, Xue-jun
收藏  |  浏览/下载:20/0  |  提交时间:2019/01/08
Modulated interaction of mu/delta opioid receptors and the drug discovery and design strategy 期刊论文
Chinese Pharmacological Bulletin, 2010, 卷号: 26, 期号: 1, 页码: 4-8
作者:  SHEN Qing;  LIU Hui-fang;  LI Wei;  LI Ying;  CHENG Jia-gao
收藏  |  浏览/下载:18/0  |  提交时间:2019/01/08
Synthesis and SAR Study of Opioid Receptor Ligands: Mono- and Bis-Indolomorphinans 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2009, 卷号: 74, 期号: 4, 页码: 335-342
作者:  Li, Fuying;  Yin, Chenlei;  Chen, Jie;  Liu, Jinggen;  Xie, Xin
收藏  |  浏览/下载:83/0  |  提交时间:2019/01/08
Synthesis and opioid receptor activity of indolopropellanes 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 卷号: 19, 期号: 16, 页码: 4603-4606
作者:  Li, Fuying;  Gaob, Linghuan;  Yin, Chenlei;  Chen, Jie;  Liu, Jinggen
收藏  |  浏览/下载:10/0  |  提交时间:2019/01/08


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