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上海药物研究所 [11]
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Ameliorating Ribosylation-Induced Amyloid-beta Pathology by Berberine via Inhibiting mTOR/p70S6K Signaling
期刊论文
JOURNAL OF ALZHEIMERS DISEASE, 2021, 卷号: 79, 期号: 2, 页码: 833-844
作者:
Wang, Yang-Yang
;
Yan, Qian
;
Huang, Zhen-Ting
;
Zou, Qian
;
Li, Jing
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/03/29
AGEs
Alzheimer's disease
amyloid-beta
autophagy
berberine
mTOR
Preliminary study on radiosensitivity to carbon ions in human breast cancer
期刊论文
JOURNAL OF RADIATION RESEARCH, 2020, 卷号: 61, 期号: 3, 页码: 399-409
作者:
Zhang, Qiuning
;
Kong, Yarong
;
Yang, Zhen
;
Liu, Yang
;
Liu, Ruifeng
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/01/12
carbon ions
breast cancer
MDA-MB-231
MCF-7
Akt/mTOR/p70S6K pathway
radiosensitivity
Discovery of nitazoxanide-based derivatives as autophagy activators for the treatment of Alzheimer's disease
期刊论文
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 4, 页码: 646-666
作者:
Li, Xiaokang
;
Lu, Jian
;
Xu, Yixiang
;
Wang, Jiaying
;
Qiu, Xiaoxia
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
Alzheimer's disease
Autophagy
Nitazoxanide
beta-amyloid
Tau protein
Blocking ROR1 enhances the roles of erlotinib in lung adenocarcinoma cell lines
期刊论文
ONCOLOGY LETTERS, 2019, 卷号: 18, 期号: 3, 页码: 2977-2984
作者:
Wang, Hui-Li
;
Liu, Yan-Chun
;
Long, Ming-Peng
;
Zheng, Chuan
;
Yang, Jia-Hui
收藏
  |  
浏览/下载:97/0
  |  
提交时间:2019/11/07
receptor tyrosine kinase-like orphan receptor 1
lung adenocarcinoma
erlotinib resistance
AKT
mammalian target of rapamycin
small interfering RNA
Aberrant modulation of ribosomal protein S6 phosphorylation confers acquired resistance to MAPK pathway inhibitors in BRAF-mutant melanoma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: Vol.40 No.2, 页码: 268-278
作者:
Gao, Ming-zhao
;
Wang, Hong-bin
;
Chen, Xiang-ling
;
Cao, Wen-ting
;
Fu, Li
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/13
BRAF-mutant melanoma
MAPK pathway inhibitors
acquired resistance
P70S6K
RSK
rpS6
G(1)/G(0) phase arrest
mTOR inhibitor
Curcumin induces apoptotic cell death and protective autophagy by inhibiting AKT/mTOR/p70S6K pathway in human ovarian cancer cells
期刊论文
ARCHIVES OF GYNECOLOGY AND OBSTETRICS, 2019, 卷号: 299, 期号: 6, 页码: 1627-1639
作者:
Liu, Li-dong
;
Pang, Ying-xin
;
Zhao, Xin-rui
;
Li, Rui
;
Jin, Cheng-juan
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/11
Curcumin
Ovarian cancer
Autophagy
AKT/mTOR/p70S6K
Apoptotic cell
death
AMP-Activated Protein Kinase Activation in Dorsal Root Ganglion Suppresses mTOR/p70S6K Signaling and Alleviates Painful Radiculopathies in Lumbar Disc Herniation Rat Model
期刊论文
SPINE, 2019, 卷号: 44, 期号: 15, 页码: E865-E872
作者:
Liu, Yuantong
;
Li, Jianmin
;
Li, Hao
;
Shang, Yue
;
Guo, Yan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/12/11
allodynia
AMP-activated protein kinase
dorsal root ganglion
hyperalgesia
lumbar disc herniation
metformin
mammalian target of
rapamycin
painful radiculopathies
paw withdrawal latency
paw
withdrawal thresholds
The oncogenic role of CB2 in the progression of non-small-cell lung cancer
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2019, 卷号: 117
作者:
Xu, Shaohua
;
Ma, Hanchen
;
Bo, Yuhong
;
Shao, Mingju
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
NSCLC
CB2
Tumor progression
Akt/mTOR/P70S6K pathway
aberrantmodulationofribosomalproteins6phosphorylationconfersacquiredresistancetomapkpathwayinhibitorsinbrafmutantmelanoma
期刊论文
中国药理学报英文版, 2019, 卷号: 040, 期号: 002, 页码: 268
作者:
Mingzhao Gao
;
Hongbin Wang
;
Xiangling Chen
;
Wenting Cao
;
Li Fu
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/07/01
BRAF-mutant
melanoma
MAPK
pathway
inhibitors
acquired
resistance
P70S6K
RSK
rpS6
G1/G0
phase
arrest
mTOR
inhibitor
Combination therapy with BH3 mimetic and hyperthermia tends to be more effective on anti-melanoma treatment
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 503, 期号: 1, 页码: 249-256
作者:
Shi, Zhen
;
Lan, Bin
;
Peng, Baowei
;
Wang, Xuefeng
;
Zhang, Ganggang
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
Melanoma
BH3 mimetic
Hyperthermia
Combination therapy
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