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厦门大学 [6]
上海药物研究所 [4]
山东大学 [4]
上海营养与健康研究所 [3]
自然资源部第一海洋研... [3]
西安交通大学 [2]
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期刊论文 [30]
学位论文 [3]
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2021 [2]
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2013 [4]
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Functionalized nanoporous gold membrane for pancreatic islet cells encapsulation
期刊论文
MATERIALS LETTERS, 2021, 卷号: 301, 页码: 3
作者:
Chen, Shi-ting
;
He, Si-yuan
;
Wang, Wan-ying
;
Jin, Hai-jun
;
Lu, Jian
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2021/10/15
Nanoporous gold
Dealloying
Cell encapsulation
Diabetes treatment
Biomaterials
Porous material
A novel GPR120-selective agonist promotes insulin secretion and improves chronic inflammation
期刊论文
LIFE SCIENCES, 2021, 卷号: 269, 页码: 8
作者:
Yang, Liu
;
Lei, Xian-Tao
;
Huang, Qi
;
Wang, Ting
;
Sun, Hong-Bin
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
GPR120 agonist
Insulin secretion
Anti-inflammation
Insulin resistance
Type 2 diabetes mellitus
Glucagon-like peptide-1 receptor agonist exendin-4 protects against interleukin-1 beta-mediated inhibition of glucose stimulated insulin secretion by mouse insulinoma beta cells
期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2017, 卷号: 14, 期号: 3
作者:
Niu, Ben
;
Li, Chao
;
Su, Heng
;
Li, Qingzhu
;
He, Qiu
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/04
exendin-4
glucagon-like peptide
interleukin-1 beta
beta-TC-6 cells
glucose-stimulated insulin secretion
Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells
期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:
Yang, Xin
;
Xu, Zhipeng
;
Zhang, Chunlan
;
Cai, Zixin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/12/03
A1c
glycated hemoglobin
AACE
American Association of Clinical Endocrinologists
ACC
acetyl-CoA carboxylase
ADA
American Diabetes Association
Akt/PKB
tyrosine kinase/protein kinase B
AMP
adenosine monophosphate
AMPK
adenosine monophosphate-activated protein
Ang II
angiotensin II
ATP
adenosine triphosphate
BAT
brown adipose tissue
CHOP
CEBP-homologous protein
CEBP
CCAAT enhancer binding protein
CoA
coenzyme A
DPP
Diabetes Prevention Program
EASD
European Association for the Study of Diabetes
eNOS
endothelial nitric oxide synthase
ER
endoplasmic reticulum
FDA
Food and Drug Administration
FFA
free fatty acid
FOXO1
forkhead box protein O1
G6P
glucose 6-phosphate
GDM
gestational diabetes mellitus
GIPR
glucose-dependent insulinotropic polypeptide receptor
GLP-1R
glucagon-like peptide-1 receptor
GLUT1
glucose transporter-1
GLUT4
glucose transporter type 4
GLUTs
glucose transporters
G6P
glucose 6-phosphate, glucose transporter-1
GPR40
G protein-coupled receptor 40
HbA1c
hemoglobin A1c
HGP
hepatic glucose production
HSL
hormone sensitive lipase
IL-6
interleukin 6
INS-1
insulinoma cells in rat
IR
insulin resistance
IRS-1
insulin receptor substrate 1
JNK
c-Jun. N-terminal kinase
Kir6.2
inwardly rectifying potassium/kalium channel
LDs
lipid droplets
LDL
low density lipoprotein
LV
left ventricular
MIN6 cells
mouse insulinoma cells
MAPK
mitogen-activated protein kinases
mPTP
mitochondrial permeability transition pore opening
mTOR
mammalian target of rapamycin
NADPH
nicotinamide adenine dinucleotide phosphate
NF-kappaB
nuclear factors-kappa B
NIT-1 cells
insulinoma cells
p70S6K
p70 ribosomal S6 kinase
PA
palmitic acid
NOS
NADPH oxidase
p38 MAPK
p38 mitogen-activated protein kinase
PA
palmitic acid
PCOS
polycystic ovary syndrome
PGC-1α
peroxisome proliferator-activated receptor-g coactivator-1α
PI3K
phosphatidylinositol 3-kinase
PKB
protein kinase B
PKC
protein kinase C
PPARα
peroxisome-proliferator activated receptor α
PTP
permeability transition pore
RCT
randomized controlled trial
RISK
reperfusion injury salvage kinase
ROS
reactive oxygen species
SERCA2
reticulum sarcoplasmic Ca2 +-ATPase
RISK
reperfusion injury salvage kinase
Smad3
mothers against decapentaplegic homolog 3
SRC-2
steroid receptor coactivator 2
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TGFβ1
transforming growth factor β1
TLR4
Toll-like receptor
TNF-α
tumor necrosis factor α
TR4
testicular receptor 4
UKPDS
United Kingdom Prospective Diabetes Study
VLDL
very low density lipoprotein
Metformin
Pancreatic β Cells
Heart failure
Insulin sensitizer
Microcystin-LR induces dysfunction of insulin secretion in rat insulinoma (INS-1) cells: Implications for diabetes mellitus
期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2016, 卷号: 314, 期号: 0, 页码: 11-21
作者:
Zhao, Yanyan
;
Shi, Kun
;
Su, Xiaomei
;
Xie, Liqiang
;
Yan, Yunjun
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2017/07/20
Niacin receptor GPR109A inhibits insulin secretion and is down-regulated in type 2 diabetic islet beta-cells
期刊论文
GENERAL AND COMPARATIVE ENDOCRINOLOGY, 2016, 卷号: 237, 页码: 98-108
作者:
Wang, Na[1]
;
Guo, De-yu[4]
;
Tian, Xiong[1]
;
Lin, Hao-peng[1]
;
Li, Yun-pan[1]
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/04/24
GPR109A
Insulin secretion
Niacin
Diabetes
Insulinoma
The insulinotrophic effect of insulin-like peptide 5 in vitro and in vivo
期刊论文
BIOCHEMICAL JOURNAL, 2015, 卷号: 466, 页码: 467-473
作者:
Luo, Xiao
;
Li, Ting
;
Zhu, Yue
;
Dai, Yunbin
;
Zhao, Jianwei
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
Type 2 diabetes mellitus
GLP-1
hypoglycaemic effect
INSL5
insulin
RXFP4
Menin通过PTN/RPTPβ/ζ信号通路调控肺癌及其自身SUMO化翻译后修饰的研究
学位论文
2015, 2013
冯子杰
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2016/02/23
menin
PTN
RPTP β/ζ
肺癌
细胞增殖及迁移
SUMO化
K591
menin
PTN
RPTP β/ζ
lung cancer
cell proliferation and migration
SUMOylaiton
K591
AICAR and Metformin Exert AMPK-dependent Effects on INS-1E Pancreatic beta-cell Apoptosis via Differential Downstream Mechanisms
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2015, 卷号: 11, 期号: 11, 页码: 1272-1280
作者:
Dai, Yu-Lu
;
Huang, Su-Ling
;
Leng, Ying
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
AICAR
Metformin
AMPK
INS-1E cells
apoptosis
IG20/MADD Plays a Critical Role in Glucose-Induced Insulin Secretion
期刊论文
http://dx.doi.org/10.2337/db13-0707, 2014
Li, Liang-cheng
;
Wang, Yong
;
Carr, Ryan
;
Haddad, Christine Samir
;
Li, Ze
;
Qian, Lixia
;
Oberholzer, Jose
;
Maker, Ajay V.
;
Wang, Qian
;
Prabhakar, Bellur S.
;
李良成
;
王勇
;
王骞
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2015/07/22
DEATH DOMAIN PROTEIN
PANCREATIC BETA-CELLS
HOMEOSTASIS MODEL ASSESSMENT
NUCLEOTIDE EXCHANGE PROTEIN
MITOGEN-ACTIVATED KINASE
THYROID-CANCER CELLS
SPLICE VARIANT
IG20 GENE
INDUCED APOPTOSIS
DENN-SV
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