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上海药物研究所 [4]
山东大学 [2]
厦门大学 [1]
大连理工大学 [1]
武汉病毒研究所 [1]
中南大学 [1]
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期刊论文 [11]
学位论文 [1]
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Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
Is level of acetylation directly correlated to radiation sensitivity of cancer cell?
期刊论文
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2019, 卷号: 813, 期号: 无, 页码: 13-19
作者:
Zhang, Fengqiu
;
Chen, Zhu
;
Shao, Changsheng
;
Huang, Qing
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/03/31
Acetylation
Radiosensitivity
HeLa cells
Histone deacetylase inhibitors (HDACis)
Trichostatin A (TSA)
HDAC inhibitor TSA ameliorates mechanical hypersensitivity and potentiates analgesic effect of morphine in a rat model of bone cancer pain by restoring μ-opioid receptor in spinal cord
期刊论文
Brain Research, 2017, 卷号: 1669, 页码: 97-105
作者:
Hou, Xinran
;
Weng, Yingqi*
;
Ouyang, Bihan
;
Ding, Zhuofeng
;
Song, Zongbin
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
BCP
bone cancer pain
TSA
trichostatin A
MOR
mu-opioid receptor
HDACs
histone deacetylases
HDACi
histone deacetylase inhibitors
PWMT
paw withdrawal mechanical threshold
PWTL
paw withdrawal thermal latency
Bone cancer pain
Mechanical hypersensitivity
Mu-opioid receptor
Histone deacetylase inhibitor
Trichostatin A
DNA methyltransferase inhibitors: an updated patent review (2012-2015)
期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2016, 卷号: 26, 期号: 9, 页码: 1017-1030
作者:
Xu, Pan
;
Hu, Guang
;
Luo, Cheng
;
Liang, Zhongjie
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
DNMT inhibitors (DNMTi)
epigenetic therapy
nucleotide derivatives
drug combination
allosteric inhibitor
Histone deacetylase inhibitor SAHA epigenetically regulates miR-17-92 cluster and MCM7 to upregulate MICA expression in hepatoma
期刊论文
The British journal of cancer, 2015, 卷号: 112, 期号: 1, 页码: 112-121
作者:
Yang, H.
;
Lan, P.
;
Hou, Z.
;
Guan, Y.
;
Zhang, J.
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/17
hepatocellular carcinoma (HCC)
histone deacetylase inhibitor (HDACi)
MICA
natural killer cells
microRNA
MCM7
The Design and Synthesis of a New Class of RTK/HDAC Dual-Targeted Inhibitors
期刊论文
MOLECULES, 2013, 卷号: 18, 期号: 6, 页码: 6491-6503
作者:
Zhang, Xuan
;
Su, Mingbo
;
Chen, Yi
;
Li, Jia
;
Lu, Wei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
receptor tyrosine kinases
histone deacetylase
antitumor
synergistic effect
dual inhibitor
Synthesis, Biological Evaluation and Molecular Modeling of Cyclic Tetrapeptide Based Inhibitors HDAC
期刊论文
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2012, 卷号: 28, 页码: 1011-1016
作者:
Li Xiao-hui
;
Wei Ying-dong
;
Wang Shi-miao
;
Wang Meng-nan
;
Huang Da-wei
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/13
Histone deacetylase(HDAC)
Histone deacetylase inhibitor(HDACI)
Cyclic tetrapeptide
Anti-cancer agent
Antiproliferative activity
Docking
CS055 (Chidamide/HBI-8000), a novel histone deacetylase inhibitor, induces G(1) arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells
期刊论文
BIOCHEMICAL JOURNAL, 2012, 卷号: 443
作者:
Gong, Ke
;
Xie, Jia
;
Yi, Hong
;
Li, Wenhua
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
apoptosis
CS055
differentiation
histone deacetylase inhibitor (HDACi)
leukaemia
proliferation inhibition
reactive oxygen species (ROS)
Histone deacetylase inhibitor activity in royal jelly might facilitate caste switching in bees
期刊论文
EMBO REPORTS, 2011, 卷号: 12, 期号: 3, 页码: 238-243
作者:
Spannhoff, Astrid
;
Kim, Yong Kee
;
Raynal, Noel J. -M.
;
Gharibyan, Vazganush
;
Su, Ming-Bo
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Apis mellifera
epigenetic
HDAC inhibitor
phenotypic plasticity
royal jelly
组蛋白去乙酰化酶抑制剂减轻急性移植物抗宿主病的实验研究
学位论文
2011, 2011
朱婕琳
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2016/02/14
组蛋白去乙酰化酶抑制剂
调节性T细胞
急性移植物抗宿主病
histione deacetylase inhibitor(HDACI)
Treg
Acute GVHD
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