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期刊论文 [28]
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Lipid-Lowering Activities of Cucurbitacins Isolated from Trichosanthes cucumeroides and Their Synthetic Derivatives
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2020, 卷号: 83, 期号: 12, 页码: 3536-3544
作者:
Zhang, Xianjing
;
Li, Huihui
;
Wang, Wenqiong
;
Chen, Tong
;
Xuan, Lijiang
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/05/24
AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Sun, Shui-mei
;
Xie, Zhi-fu
;
Zhang, Yang-ming
;
Zhang, Xin-wen
;
Zhou, Chen-dong
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/12/24
adenosine 5 '-monophosphate-activated protein kinase
AMPK activator
C24
liver
triglycerides
cholesterol
VLDL
hypolipidemic drug
metabolic syndrome
23,24-Dihydrocucurbitacin B promotes lipid clearance by dual transcriptional regulation of LDLR and PCSK9
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 327-335
作者:
Li, Hui-hui
;
Li, Jun
;
Zhang, Xian-jing
;
Li, Jiao-meng
;
Xi, Cong
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
23,24-dihydrocucurbitacin B
lipid-lowering agent
LDLR
PCSK9
HNF1 alpha
SREBP2
2324dihydrocucurbitacinbpromoteslipidclearancebydualtranscriptionalregulationofldlrandpcsk9
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 3, 页码: 327
作者:
Li Huihui
;
Li Jun
;
Zhang Xianjing
;
Li Jiaomeng
;
Xi Cong
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/07/01
23
24-dihydrocucurbitacin B
lipid-lowering agent
LDLR
PCSK9
HNF1α
SREBP2
Inhibition of HSP90 beta Improves Lipid Disorders by Promoting Mature SREBPs Degradation via the Ubiquitin-proteasome System
期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 20, 页码: 5769-5783
作者:
Zheng, Zu-Guo
;
Zhang, Xin
;
Liu, Xiao-Xiao
;
Jin, Xiu-Xiu
;
Dai, Lunzhi
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
HSP90 beta
lipid metabolism
corylin
SREBPs
proteasomal degradation
Proteomics analysis reveals a potential new target protein for the lipid-lowering effect of Berberine8998
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 9, 页码: 1473-1482
作者:
Yu, Cheng-yin
;
Liu, Gang-yi
;
Liu, Xiao-hui
;
Gui, Yu-zhou
;
Liu, Hai-ming
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
berberine
berberine8998
proteomics
lipid-lowering
cholesterol
triglycerides
LDL-C
fatty acid metabolism
hypercholesterolemia
obesity
Enhanced Single-Step Bioproduction of the Simvastatin Precursor Monacolin J in an Industrial Strain of Aspergillus terreus by Employing the Evolved Lovastatin Hydrolase
期刊论文
BIOTECHNOLOGY JOURNAL, 2018, 卷号: 13, 期号: 6
作者:
Liang, Bo
;
Huang, Xuenian
;
Teng, Yun
;
Liang, Yajing
;
Yang, Yong
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2018/12/21
Aspergillus Terreus
Directed Evolution
Lovastatin Hydrolase
Monacolin j
Simvastatin
Plant Sterols: Chemical and Enzymatic Structural Modifications and Effects on Their Cholesterol-Lowering Activity
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018, 卷号: 66, 期号: 12, 页码: 3047-3062
作者:
He, Wen-Sen[1]
;
Zhu, Hanyue[2]
;
Chen, Zhen-Yu[3]
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/24
plant sterols
phytosterol esters
chemical modification
cholesterol-lowering activity
cholesterol
proteomicsanalysisrevealsapotentialnewtargetproteinforthelipidloweringeffectofberberine8998
期刊论文
actapharmacologicasinica, 2018, 卷号: 39, 期号: 9, 页码: 1473
作者:
u Chengyin
;
Liu Gangyi
;
Liu Xiaohui
;
Gui Yuzhou
;
Liu Haiming
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/07/01
DISEASE
ATHEROSCLEROSIS
IDENTIFICATION
CHALLENGES
EFFICACY
RECEPTOR
berberine
berberine8998
proteomics
lipid-lowering
cholesterol
triglycerides
LDL-C
fatty acid metabolism
hypercholesterolemia
obesity
Single-step production of the simvastatin precursor monacolin J by engineering of an industrial strain of Aspergillus terreus
期刊论文
METABOLIC ENGINEERING, 2017, 卷号: 42, 页码: 109-114
作者:
Huang, Xuenian
;
Liang, Yajing
;
Yang, Yong
;
Lu, Xuefeng
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2017/12/14
Monacolin j
Simvastatin
Lovastatin Hydrolase
Aspergillus Terreus
Microbial Cell Factory
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