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上海药物研究所 [2]
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期刊论文 [8]
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Differences in the In Vivo and In Vitro Metabolism of Imrecoxib in Humans: Formation of the Rate-Limiting Aldehyde Intermediate
期刊论文
DRUG METABOLISM AND DISPOSITION, 2018, 卷号: 46, 期号: 9, 页码: 1320-1328
作者:
Hou, Xiangyu
;
Zhou, Jialan
;
Yu, Songda
;
Zhou, Lei
;
Zhang, Yifan
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2019/01/08
Dynamic regulation of fatty acid pools for improved production of fatty alcohols in Saccharomyces cerevisiae
期刊论文
Microbial Cell Factories, 2017, 卷号: 16, 期号: 1
作者:
Zhou,Yongjin J.
;
Nielsen,Jens
;
Teixeira,Paulo Gon?alves
;
Ferreira,Raphael
;
Siewers,Verena
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/06/20
Fatty alcohols
Fatty acid activation
FAA1
Dynamic control
Yeast
Metabolic engineering
De novo biosynthesis of Gastrodin in Escherichia coli
期刊论文
METABOLIC ENGINEERING, 2016, 卷号: 35, 页码: 138-147
作者:
Bai, Yanfen
;
Yin, Hua
;
Bi, Huiping
;
Zhuang, Yibin
;
Liu, Tao
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2017/03/13
Gastrodin
Chorismate
Metabolic engineering
Glycosyltransferase
Directed evolution
Escherichia coli
Synthesis of alpha,beta-unsaturated esters via a chemo-enzymatic chain elongation approach by combining carboxylic acid reduction and Wittig reaction
期刊论文
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 2015, 卷号: 11, 页码: 2245-2251
作者:
Duan, Yitao
;
Yao, Peiyuan
;
Du, Yuncheng
;
Feng, Jinhui
;
Wu, Qiaqing
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2016/06/23
alpha,beta-unsaturated esters
carboxylic acid reductase
chemoenzymatic synthesis
reduction
Wittig reaction
Metabolic disposition and excretion of quinocetone in rats, pigs, broilers, and carp
期刊论文
Food and Chemical Toxicology, 2014, 卷号: 69, 页码: 109-119
作者:
Li, Juan
;
Huang, Lingli
;
Wang, Xu
;
Pan, Yuanhu
;
Liu, Zhaoying
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/23
QCT (Q0)
quinocetone
Q1
1-desoxyquinocetone
Q2
dideoxyquinocetone
Q3
carbonyl-reduced metabolites of 1-deoxyquinocetone
Q4
carbonyl- and double-bond-reduced metabolites of 1-deoxyquinocetone
Q5
carbonyl-reduced metabolites of dideoxyquinocetone
Q6
phenyl ring hydroxylation metabolites of carbonyl-reduced quinocetone
Q7
carbonyl-reduced quinocetone
Q8
double-bond-reduced metabolite of 4-deoxyquinocetone
Q9
phenyl ring hydroxylation metabolites of quinocetone
OLA
olaquindox
CBX
carbadox
QdNOs
quinoxaline 1,4-dioxides
MQCA
3-methylquinoxaline-2-carboxylic acid
MEQ
mequindox
QCA
quinoxalie-2-carboxylic acid
CYA
cyadox
JECFA
Joint FAO/WHO Expert Committee on Food Additives
VICH
International Cooperation on Harmonization of Technical Requirements for the Registration of Veterinary Medicinal Products
LSC
liquid scintillation counting
EIC
extracted ion chromatograms
CYP
cytochrome P450 enzyme
CBR
carbonyl reductase
H2O2
hydrogen peroxide
ROS
reactive oxygen species
Quinocetone
Radioactivity isotope tracing
Disposition
Metabolism
Excretion
Toxicology
Microbial production of cis-1,2-dihydroxy-cyclohexa-3,5-diene-1-carboxylate by genetically modified Pseudomonas putida
期刊论文
2010, 2010, OCT
Sun, Shang-Yu
;
Zhang, Xin
;
Zhou, Qin
;
Chen, Jin-Chun
;
Chen, Guo-Qiang
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  |  
浏览/下载:5/0
  |  
提交时间:2017/06/15
Pseudomonas putida
benzoate dioxygenase
cis-diol dehydrogenase
biotransformation
cis-1,2-dihydroxy-cyclohexa-3,5-diene-1-carboxylic acid
DHCDC
CYTOCHROME-C-REDUCTASE
BENZOATE 1,2-DIOXYGENASE
ESCHERICHIA-COLI
CIS-DIOLS
AROMATIC-COMPOUNDS
DIOXYGENASE GENES
ACID
BIOTRANSFORMATION
BACTERIA
TOLUENE
Biotechnology & Applied Microbiology
Enantiocomplementary preparation of (s)- and (r)-mandelic acid derivatives via alpha-hydroxylation of 2-arylacetic acid derivatives and reduction of alpha-ketoester using microbial whole cells
期刊论文
Tetrahedron-asymmetry, 2007, 卷号: 18, 期号: 21, 页码: 2537-2540
作者:
Chen, Yongzheng
;
Xu, Jinggang
;
Xu, Xiaoying
;
Xia, Yu
;
Lin, Hui
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  |  
浏览/下载:28/0
  |  
提交时间:2019/05/10
Reversible long-term toxicity of epristeride in beagle dogs
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 1999, 卷号: 154, 期号: 2, 页码: 145-152
作者:
Sun, ZY
;
Feng, J
;
Qi, XD
;
Wu, HY
;
Zheng, WJ
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
epristeride
DNA
target cell toxicity
cytotoxicity
prostatic specific antigen (PSA)
dihydrotestosterone (DHT)
dogs
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