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上海药物研究所 [42]
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Low molecular weight fucoidan restores diabetic endothelial glycocalyx by targeting neuraminidase2: A new therapy target in glycocalyx shedding
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2024, 页码: 17
作者:
Li, Zhi
;
Wu, Ning
;
Wang, Jing
;
Yue, Yang
;
Geng, Lihua
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/04/07
diabetic vascular complication
glycocalyx
insulin resistance
LMWF
NEU2
A Gas Chromatography Flame Ionization Detector Method for Rapid Simultaneous Separation and Determination of Six Active Ingredients of Anticold Drug
期刊论文
CURRENT PHARMACEUTICAL ANALYSIS, 2022, 卷号: 18, 期号: 1, 页码: 71-81
作者:
Yang, Fatang
;
Du, Xiaoyun
;
Wang, Zhen
;
Dong, Yuming
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2022/03/01
Gas chromatography
flame ionization detector
active ingredients
anti-cold drug
sensitivity
precision
Absorption, distribution, metabolism, and excretion of [C-14]NBP (3-n-butylphthalide) in rats
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2021, 卷号: 1181, 页码: 9
作者:
Tian, Junjun
;
Lei, Peng
;
He, Yifei
;
Zhang, Ning
;
Ge, Xinyu
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  |  
浏览/下载:49/0
  |  
提交时间:2021/11/04
3-n-butylphthalide (NBP)
[C-14]NBP
Pharmacokinetics
Tissue distribution
Metabolism
Mass balance
Anti-nociceptive, anti-inflammatory and anti-arthritic activities of pregnane glycosides from the root bark of Periploca sepium Bunge
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 265, 页码: 12
作者:
Lin, Ze-min
;
Liu, Yu-ting
;
Huang, Yue-teng
;
Yang, Xiao-qian
;
Zhu, Feng-hua
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  |  
浏览/下载:43/0
  |  
提交时间:2021/05/24
Periploca sepium Bunge
Pregnane glycosides
Anti-nociceptive activity
Anti-inflammatory activity
Anti-arthritic activity
Inflammatory arthritis
Clinical application of pyrrole-hemoglobin adducts as a biomarker of pyrrolizidine alkaloid exposure in humans
期刊论文
ARCHIVES OF TOXICOLOGY, 2020, 页码: 7
作者:
Ma, Jiang
;
Zhang, Wei
;
He, Yisheng
;
Zhu, Lin
;
Zhang, Chunyuan
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  |  
浏览/下载:44/0
  |  
提交时间:2020/12/24
Pyrrolizidine alkaloids
Liver injury
Diagnostic biomarkers
Pyrrole-hemoglobin adducts
Pyrrole-plasma protein adducts
Pharmacokinetics and tissue distribution of remdesivir and its metabolites nucleotide monophosphate, nucleotide triphosphate, and nucleoside in mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 6
作者:
Hu, Wen-juan
;
Chang, Lu
;
Yang, Ying
;
Wang, Xin
;
Xie, Yuan-chao
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  |  
浏览/下载:51/0
  |  
提交时间:2020/12/21
remdesivir
pharmacokinetics
tissue distribution
nucleotide monophosphate
nucleotide triphosphate
nucleoside
Simultaneous determination of sutetinib and its active metabolite sutetinibN-oxide in human plasma by liquid chromatography-tandem mass spectrometry: Evaluation of plasma stability
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020, 页码: 9
作者:
Qiu, Yanan
;
Tang, Chongzhuang
;
Li, Ranran
;
Cao, Sumin
;
Zhang, Yuqiang
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/12/24
LC-MS
MS
N-oxide
stability
sutetinib
DGAT1 inhibitors protect pancreatic beta-cells from palmitic acid-induced apoptosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Huang, Jun-shang
;
Guo, Bin-bin
;
Wang, Gai-hong
;
Zeng, Li-min
;
Hu, You-hong
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2020/12/24
type 2 diabetes
DGAT1 inhibitors
pancreatic beta-cells
apoptosis
ER stress
inflammation
帕金森病靶向输递体系用于基因-化药协同治疗的研究
学位论文
: 中国科学院大学, 2020
作者:
刘霖颖
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/09/07
帕金森病,Sirna,联合递送,仿生设计
Optimization and mechanism of postponing aging of polysaccharides from Chinese herbal medicine formula
期刊论文
TOXICOLOGY RESEARCH, 2020, 卷号: 9, 期号: 3, 页码: 239-248
作者:
Pu, Xiuying
;
Luo, Amiao
;
Su, Hui
;
Zhang, Kaili
;
Tian, Changyi
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/03/01
polysaccharide
optimization
orthogonal design
anti-aging
D-galactose
aging rats
mechanism
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