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Quantitative hypoxia mapping using a self-calibrated activatable nanoprobe 期刊论文
Journal of Nanobiotechnology, 2022, 卷号: 20, 期号: 1
作者:  Feng,Xin;  Li,Yuhao;  Zhang,Shiyuan;  Li,Changjian;  Tian,Jie
收藏  |  浏览/下载:18/0  |  提交时间:2022/06/06
Deep learning radiomic nomogram can predict the number of lymph node metastasis in locally advanced gastric cancer: an international multicenter study 期刊论文
ANNALS OF ONCOLOGY, 2020, 卷号: 31, 期号: 7, 页码: 912-920
作者:  Dong, Di;  Fang, Mengjie;  Tang, Lei;  Shan, Xiuhong
收藏  |  浏览/下载:57/0  |  提交时间:2020/07/20
Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios may aid in identifying patients with non-small cell lung cancer and predicting Tumor-Node-Metastasis stages 期刊论文
ONCOLOGY LETTERS, 2018, 卷号: 16, 期号: 1
作者:  Xu, Fei;  Xu, Pengliang;  Cui, Wenqiang;  Gong, Weiyi;  Wei, Ying
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/05
Identification of metabolism-associated genes and pathways involved in different stages of clear cell renal cell carcinoma. 期刊论文
ONCOLOGY LETTERS, 2018, 期号: 15, 页码: 2316-2322
作者:  HUI-JUAN LI;  JING-FEI HUANG;  SHAO-XING DAI;  YI-CHENG GUO;  JUN-JUAN ZHENG
收藏  |  浏览/下载:22/0  |  提交时间:2018/09/25
Clinicopathological significance and potential drug target of CDH1 in breast cancer: a meta-analysis and literature review 期刊论文
Drug Design, Development and Therapy, 2015, 卷号: 9, 页码: 5277-5285
作者:  Huang, Ruixue;  Ding, Ping;  Yang, Fei*
收藏  |  浏览/下载:15/0  |  提交时间:2019/12/03
CDH1  as a tumor suppressor gene  contributes sporadic breast cancer (BC) progression. However  the association between CDH1 hypermethylation and BC  and its clinicopathological significance remains unclear. We conducted a meta-analysis to investigate the relationship between the CDH1 methylation profile and the major clinicopathological features. A detailed literature was searched through the electronic databases PubMed  Web of Science™  and EMBASE™ for related research publications. The data were extracted and assessed by two reviewers independently. Odds ratios (ORs) with corresponding confidence intervals (CIs) were calculated and summarized respectively. The frequency of CDH1 methylation was significantly higher in invasive ductal carcinoma than in normal breast tissues (OR =5.83  95% CI 3.76–9.03  P<0.00001). CDH1 hypermethylation was significantly higher in estrogen receptor (ER)-negative BC than in ER-positive BC (OR =0.62  95% CI 0.43–0.87  P=0.007). In addition  we found that the CDH1 was significantly methylated in HER2-negative BC than in HER2-positive BC (OR =0.26  95% CI 0.15–0.44  P<0.00001). However  CDH1 methylation frequency was not associated with progesterone receptor (PR) status  or with grades  stages  or lymph node metastasis of BC patients. Our results indicate that CDH1 hypermethylation is a potential novel drug target for developing personalized therapy. CDH1 hypermethylation is strongly associated with ER-negative and HER2-negative BC  respectively  suggesting CDH1 methylation status could contribute to the development of novel therapeutic approaches for the treatment of ER-negative or HER2-negative BC with aggressive tumor biology.  
Bcl-xL overexpression and its association with the progress of tongue carcinoma 期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2014, 卷号: 7, 期号: 11, 页码: 7360-7377
作者:  Zhang, KL;  Jiao, KL;  Xing, ZK;  Zhang, L;  Yang, J
收藏  |  浏览/下载:12/0  |  提交时间:2015/12/29
Differentiation of Reactive and Tumor Metastatic Lymph Nodes with Diffusion-weighted and SPIO-Enhanced MRI 期刊论文
http://dx.doi.org/10.1007/s11307-012-0562-2, 2013
Zhang, Fan; Zhu, Lei; Huang, Xinglu; Niu, Gang; Chen, Xiaoyuan; 张凡
收藏  |  浏览/下载:2/0  |  提交时间:2015/07/22
LC-MS/MS法测定不同肿瘤组织中脱氨神经氨酸、N-乙酰基神经氨酸、N-羟乙酰基神经氨酸的含量及其意义 学位论文
2011, 2011
王芳
收藏  |  浏览/下载:5/0  |  提交时间:2013/07/09
Metadherin Promotes Hepatocellular Carcinoma Metastasis through Induction of Epithelial-Mesenchymal Transition 期刊论文
CLINICAL CANCER RESEARCH, 2011, 卷号: 17, 期号: 23, 页码: 7294-7302
作者:  Zhu, K;  Dai, Z;  Pan, Q;  Wang, Z;  Yang, GH
收藏  |  浏览/下载:13/0  |  提交时间:2015/07/22
JAK1、p-STAT 3和bcl-2在胃癌中的表达及意义 期刊论文
2010, 2010
乔燕燕; 贾黾泽; 马秀梅; 冯璞; QIAO Yan-yan; JIA Min-ze; MA Xiu-mei; FENG Pu
收藏  |  浏览/下载:2/0


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