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Tetramethylpyrazine attenuates blood-brain barrier disruption in ischemia/ reperfusion injury through the JAK/STAT signaling pathway 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2019, 卷号: 854
作者:  Gong, Pian;  Zhang, Zhan;  Zou, Yichun;  Tian, Qi;  Han, Shoumeng
收藏  |  浏览/下载:23/0  |  提交时间:2019/12/05
Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance 期刊论文
European Journal of Medicinal Chemistry, 2017, 卷号: 135, 页码: 34-48
作者:  Zha, Gao-Feng;  Qin, Hua-Li*;  Youssif, Bahaa G. M.;  Amjad, Muhammad Wahab;  Raja, Maria Abdul Ghafoor
收藏  |  浏览/下载:14/0  |  提交时间:2019/12/04
Epidermal growth factor receptor (EGFR)  BRAF  Focal adhesion kinase (FAK)  Tubulin polymerization  Cancer cell lines  MDR  multidrug resistance  EGFR  epidermal growth factor receptor  EMEA  European Medicines Evaluation Agency  FDA  US Food and Drug Administration  NSCLC  non-small cell lung  FAK  focal adhesion kinase  RTK  receptor tyrosine kinases  MAPK  mitogen-activated protein kinase  ABC  ATP-binding cassette  NF-kB  NF-kappaB  FERM  Four-point-one, ezrin, radixin, moesin  TMP  Ligustrazine or tetramethylpyrazine  Adr  Adriamycin  DRS  death receptors  TFN  tumor necrosis factor  PI  propidium iodide  TKIs  tyrosine kinase inhibitors  FAR  fluorescence activity ratio  HRMS  high resolution mass spectra  TLC  thin layer chromatography  UV  ultraviolet  DMEM  Dulbecco's modified Eagle's medium  DMSO  dimethyl sulfoxide  IBX  2-iodoxybenzoic acid  
Tetramethylpyrazine can ameliorate hepatocellular mitochondrial dysfunction by decreasing the inflammatory response and increasing AQP8 protein expression in septic rats 期刊论文
EUROPEAN JOURNAL OF INFLAMMATION, 2017, 卷号: 15, 期号: 3, 页码: 179-191
作者:  Tao, Xiaogen;  Li, Kun;  Wang, Jinquan;  Zhang, Lin;  Li, Wei
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/11
2,3,5,6-Tetramethylpyrazine (TMP) down-regulated arsenic-induced heme oxygenase-1 and ARS2 expression by inhibiting Nrf2, NF-kappa B, AP-1 and MAPK pathways in human proximal tubular cells 期刊论文
ARCHIVES OF TOXICOLOGY, 2016, 卷号: 90, 期号: 9
作者:  Gong, Xuezhong;  Ivanov, Vladimir N.;  Hei, Tom K.
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/05
2,3,5,6-Tetramethylpyrazine (TMP) down-regulated arsenic-induced heme oxygenase-1 and ARS2 expression by inhibiting Nrf2, NF-κB, AP-1 and MAPK pathways in human proximal tubular cells 期刊论文
Archives of toxicology, 2016, 卷号: 90, 页码: 2187-2200
作者:  Gong Xuezhong[1];  Ivanov Vladimir N[2];  Hei Tom K[3]
收藏  |  浏览/下载:2/0  |  提交时间:2019/04/26
Tetramethylpyrazine (TMP) protects against sodium arsenite-induced nephrotoxicity by suppressing ROS production, mitochondrial dysfunction, pro-inflammatory signaling pathways and programed cell death 期刊论文
ARCHIVES OF TOXICOLOGY, 2015, 卷号: 89, 期号: 7
作者:  Gong, Xuezhong;  Ivanov, Vladimir N.;  Davidson, Mercy M.;  Hei, Tom K.
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/05
Novel Tandem Biotransformation Process for the Biosynthesis of a Novel Compound, 4-(2,3,5,6-Tetramethylpyrazine-1)-4 '-Demethylepipodophyllotoxin 期刊论文
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2011, 卷号: 77, 期号: 9, 页码: 3023-3034
作者:  Tang, Ya-Jie;  Zhao, Wei;  Li, Hong-Mei
收藏  |  浏览/下载:14/0  |  提交时间:2013/11/06
Tetramethylpyrazine protects palmitate-induced oxidative damage and mitochondrial dysfunction in C2C12 myotubes 期刊论文
LIFE SCIENCES, 2011, 卷号: 88, 期号: 17-18, 页码: 803-809
作者:  Gao, Xin;  Zhao, Xiao-long;  Zhu, Yan-hui;  Li, Xiao-mu;  Xu, Qiong
收藏  |  浏览/下载:11/0  |  提交时间:2019/01/08
Microemulsion-based novel transdermal delivery system of tetramethylpyrazine: preparation and evaluation in vitro and in vivo 期刊论文
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2011, 卷号: 6
作者:  Zhao, Ji-Hui;  Ji, Li;  Wang, Hui;  Chen, Zhi-Qiang;  Zhang, Yong-Tai
收藏  |  浏览/下载:12/0  |  提交时间:2019/12/05
Microemulsion-based novel transdermal delivery system of tetramethylpyrazine: preparation and evaluation in vitro and in vivo 期刊论文
International journal of nanomedicine, 2011, 卷号: 6, 页码: 1611-9
作者:  Zhao Ji-Hui[1];  Ji Li[2];  Wang Hui[3];  Chen Zhi-Qiang[4];  Zhang Yong-Tai[5]
收藏  |  浏览/下载:3/0  |  提交时间:2019/04/30


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