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科研机构
复旦大学上海医学院 [3]
中国科学院大学 [2]
中南大学 [2]
昆明动物研究所 [2]
北京大学 [1]
昆明植物研究所 [1]
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期刊论文 [13]
发表日期
2018 [1]
2017 [1]
2016 [2]
2015 [1]
2014 [1]
2013 [1]
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Pharmacolo... [1]
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A novel alpha-conopeptide Eu1.6 inhibits N-type (Ca(V)2.2) calcium channels and exhibits potent analgesic activity
期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8
作者:
Liu, Zhuguo
;
Bartels, Peter
;
Sadeghi, Mahsa
;
Du, Tianpeng
;
Dai, Qing
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2018/11/05
A Novel Toxin from Haplopelma lividum Selectively Inhibits the NaV1.8 Channel and Possesses Potent Analgesic Efficacy
期刊论文
Toxins, 2017, 卷号: 9, 期号: X, 页码: e7
作者:
Meng P
;
Huang HG
;
Liu JZ[*]
;
Lai R[*]
;
Rong MQ[*]
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2017/01/09
NaV1.8
analgesia
neurotoxin
spider
venom
Phenolic acids isolated from the fungus Schizophyllum commune exert analgesic activity by inhibiting voltage-gated sodium channels
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2016, 卷号: 14, 期号: 9, 页码: 661-670
作者:
Yao Hui-Min
;
Wang Gan
;
Liu Ya-Ping
;
Rong Ming-Qiang
;
Shen Chuan-Bin
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2017/01/05
Schizophyllum commune
Sodium channel
Phenolic acids
Painf
Phenolic acids isolated from the fungus Schizophyllum commune exert analgesic activity by inhibiting voltage-gated sodium channels
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2016, 卷号: 14, 期号: 9, 页码: 661−670
作者:
Yao HM
;
Wang G
;
Yan XW
;
Luo XD[*]
;
Lai R[*]
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2016/09/28
Pain
Phenolic acids
Schizophyllum commune
Sodium channel
Dexmedetomidine inhibits Tetrodotoxin-resistant Na(v)1.8 sodium channel activity through G(i/o)-dependent pathway in rat dorsal root ganglion neurons
期刊论文
MOLECULAR BRAIN, 2015, 卷号: 8
作者:
Gu, Xi-Yao
;
Liu, Ben-Long
;
Zang, Kai-Kai
;
Yang, Liu
;
Xu, Hua
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/19
alpha 2-adrenoceptor
Dexmedetomidine
Dorsal root ganglion
Pain
Tetrodotoxin-resistant (TTX-R) sodium channel Na(v)1.8
Whole-cell recording
Huwentoxin-XVI, an analgesic, highly reversible mammalian N-type calcium channel antagonist from Chinese tarantula Ornithoctonus huwena
期刊论文
Neuropharmacology, 2014, 卷号: 79, 页码: 657-667
作者:
Deng, Meichun*
;
Luo, Xuan
;
Xiao, Yucheng
;
Sun, Zhenghua
;
Jiang, Liping
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/03
HWTX-XVI
Tarantula toxin
N-type calcium channels
Dorsal root ganglia
Rat vas deferens
Pain model
Analgesic action
HWTX
Huwentoxin
ICK
inhibitor cystine knot
Cav channel
voltage-gated calcium channel
Nav channel
voltage-gated sodium channel
DRG
dorsal root ganglion
TTX
tetrodotoxin
TTX-R
TTX-resistant
TTX-S
TTX-sensitive
IC50
median inhibitory concentration
Kv channel
voltage-gated potassium channel
HPLC
high pressure liquid chromatography
MALDI-TOF
matrix assisted laser desorption/ionization time-of-flight
Synthesis and biological characterization of synthetic analogs of Huwentoxin-IV (Mu-theraphotoxin-Hh2a), a neuronal tetrodotoxin-sensitive sodium channel inhibitor
期刊论文
Toxicon, 2013, 卷号: 71, 页码: 57-65
作者:
Deng, Meichun*
;
Luo, Xuan
;
Jiang, Liping
;
Chen, Hanchun
;
Wang, Jun
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/03
DRG
Dorsal root ganglion
HPLC
HWTX
HWTX-IV
High pressure liquid chromatography
Huwentoxin
IC(50)
ICK
Inhibitor cystine knot
Kv channel
MALDI-TOF
Matrix assisted laser desorption/ionization time-of-flight
Median inhibitory concentration
Mutant
Patch-clamp
Protein folding
Solid-phase peptide synthesis
TTX
TTX-R
TTX-S
TTX-resistant
TTX-sensitive
Tetrodotoxin
VGSC
Voltage-gated potassium channel
Voltage-gated sodium channel
PKC epsilon-dependent potentiation of TTX-resistant Na(v)1.8 current by neurokinin-1 receptor activation in rat dorsal root ganglion neurons
期刊论文
MOLECULAR PAIN, 2009, 卷号: 5
作者:
Cang, Chun-Lei
;
Zhang, Hua
;
Zhang, Yu-Qiu
;
Zhao, Zhi-Qi
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/19
JZTX-IV, a unique acidic sodium channel toxin isolated from the spider Chilobrachys jingzhao
期刊论文
toxicon, 2008
Wang, Meichi
;
Diao, Jianbo
;
Li, Jiang
;
Tang, Jianzhou
;
Lin, Yin
;
Hu, Weijun
;
Zhang, Yongqun
;
Xiao, Yucheng
;
Liang, Songping
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/11/12
JZTX-IV
TTX-R
TTX-S
Sodium channel
DRG
Cardiac myocyte
GATED NA+ CHANNELS
GATING MODIFIER
SELENOCOSMIA-HUWENA
BINDING
NEUROTOXINS
ACTIVATION
DIVERSITY
SEQUENCE
VENOM
The anti-nociceptive effect of bmk as, a scorpion active polypeptide, and the possible mechanism on specifically modulating voltage-gated na+ currents in primary afferent neurons
期刊论文
Peptides, 2006, 卷号: 27, 期号: 9, 页码: 2182-2192
作者:
Chen, Jin
;
Feng, Xing-Hua
;
Shi, Jian
;
Tan, Zhi-Yong
;
Bai, Zhan-Tao
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/05/10
Scorpion toxin
Sodium channel
Anti-nociception
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