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昆明动物研究所 [6]
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上海药物研究所 [3]
中国水产科学院 [3]
南海海洋研究所 [2]
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期刊论文 [32]
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牡蛎温度适应性状关键基因调控机制解析
学位论文
中国科学院海洋研究所: 中国科学院大学, 2024
作者:
王朝刚
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/06/06
长牡蛎
福建牡蛎
温度适应
种间分化
多层级分子调控
Kaempferol and Kaempferide Attenuate Oleic Acid-Induced Lipid Accumulation and Oxidative Stress in HepG2 Cells
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 卷号: 22, 期号: 16
作者:
Tie, Fangfang
;
Ding, Jin
;
Hu, Na
;
Dong, Qi
;
Chen, Zhi
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/11/18
NAFLD
kaempferol
kaempferide
lipid accumulation
oxidative stress
molecular docking
Leucosceptroid B from glandular trichomes of Leucosceptrum canum reduces fat accumulation in Caenorhabditis elegans through suppressing unsaturated fatty acid biosynthesis
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 12, 页码: 892-899
作者:
Ling Yi
;
Teng Lin-Lin
;
Hua Juan
;
Li De-Sen
;
Luo Shi-Hong
收藏
  |  
浏览/下载:115/0
  |  
提交时间:2020/03/18
Sesterterpenoid
Leucosceptroid B
Leucosceptrum canum
Caenorhabditis elegans
Fat accumulation
Fatty acid biosynthesis
Antilipemic agent
Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
作者:
Yang, Xiao-Nan
;
Wang, Yi-Kun
;
Zhu, Xu
;
Xiao, Xue-Rong
;
Dai, Man-Yun
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/03/26
Sorafenib kills liver cancer cells by disrupting SCD1-mediated synthesis of monounsaturated fatty acids via the ATP-AMPK-mTOR-SREBP1 signaling pathway
期刊论文
FASEB JOURNAL, 2019, 卷号: 33, 期号: 9, 页码: 10089-10103
作者:
Liu, Ge
;
Kuang, Shan
;
Cao, Ruobing
;
Wang, Ju
;
Peng, Quancai
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2019/11/14
stearoyl CoA desaturase 1
monounsaturated FAs
ATP production
(5R)-5-hydroxytriptolide ameliorates liver lipid accumulation by suppressing lipid synthesis and promoting lipid oxidation in mice
期刊论文
LIFE SCIENCES, 2019, 卷号: 232, 页码: 9
作者:
Dong, Yunxia
;
Lu, Henglei
;
Li, Qiang
;
Qi, Xinming
;
Li, Yuanchao
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
(5R)-5-hydroxytriptolide
NAFLD
Lipid synthesis
Fatty acids oxidation
Fat deposition
Glycerol kinase 5 confers gefitinib resistance through SREBP1/SCD1 signaling pathway
期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2019, 卷号: 38
作者:
Hu, Jie
;
Zhou, Jian
;
Qu, Guimei
;
Zhang, Ge
;
Wu, Zuoren
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/05
Non-small cell lung cancer
Glycerol kinase 5
Gefitinib
Stearoyl-CoA desaturase-1
A hint from zebrafish models of hepatic tumorigenesis: Targeting stearoyl-CoA desaturase.
期刊论文
Oncotarget, 2019, 卷号: Vol.10 No.9, 页码: 924-925
作者:
Kunpeng Lv
;
Fei Fei
;
Xu Wang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/13
Ras
Scd
Wnt
hepatic tumorigenesis
zebrafish
mir378转基因小鼠脂肪组织的代谢表型分析
期刊论文
中国细胞生物学学报, 2019, 卷号: 41, 期号: 7, 页码: 1377
作者:
汪瑞婷
;
宋懿朋
;
李常银
;
李虎
;
贾海雪
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2020/01/14
Dietary supplementation of A-type procyanidins from litchi pericarp improves glucose homeostasis by modulating mTOR signaling and oxidative stress in diabetic ICR mice
期刊论文
Journal of Functional Foods, 2018, 卷号: 44, 页码: 155-165
作者:
Li, Xiaopeng
;
Wu, Qian
;
Sui, Yong
;
Li, Shuyi
;
Xie, Bijun
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/12/27
A-type procyanidins
Oxidative stress
Glucose homeostasis
Type 2 diabetes
mTOR
ACC1
acetyl coenzyme A carboxylase 1
ACL
ATP-citrate lyase
ALT
alanine aminotransferase
AST
aspartate aminotransferase
AUC
area under curve
BAT
brown adipose tissue
FAS
fatty acid synthase
FFA
free fatty acid
FoxO3a
Forkhead box O3a
FoxO1a
Forkhead box O3a
PKCβ
protein kinase C β
mTOR
mechanistic target of rapamycin
HDL
high-density lipoprotein
GHbA1c
glycated hemoglobin A1c
GK
glucokinase
G-6-Pase
glucose-6-phosphatase
GLP-1
glucagon-like peptide-1
GSH-PX
total glutathione peroxidase
HOMA-IR
homeostatic model assessment of insulin resistance
LDHA
lactate dehydrogenase
LDL
low-density lipoprotein
LPOPC
oligomeric procyanidins of litchi pericarp
MDA
malondialdehyde
MnSOD
manganese superoxide dismutase
mTOR
mechanistic target of rapamycin
OGTT
oral glucose tolerance test
PDH
pyruvate dehydrogenase
PEPCK
phosphoenolpyruvate carboxykinase
PFK
phosphofructokinase
PK
pyruvate kinase
PKCβ
protein kinase C β
PPG
postprandial blood glucose
S6K1
S6 Kinase 1
PKCβ
protein kinase C β
RTK
receptor tyrosine kinase
SREBP-1c
sterol regulatory element-binding protein 1c
ACL
ATP-citrate lyase
ACC1
acetyl coenzyme A carboxylase 1
FAS
fatty acid synthase
SCD1
stearoyl CoA desaturase 1
STZ
streptozotocin
S6K1
S6 kinase 1
PPG
postprandial blood glucose
ROS
reactive oxygen species
TC
total cholesterol
TG
triacylglycerol
STZ
streptozotocin
T-AOC
total antioxidant capacity
T-SOD
total superoxide dismutase
UCP-1
uncoupling protein 1
WAT
white adipose tissue
XOS
xylo-oligosaccharides
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