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科研机构
上海药物研究所 [11]
山东大学 [5]
厦门大学 [3]
合肥物质科学研究院 [3]
江苏大学 [2]
复旦大学上海医学院 [2]
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期刊论文 [39]
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2022 [1]
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CircVAPA promotes small cell lung cancer progression by modulating the miR-377-3p and miR-494-3p/IGF1R/AKT axis
期刊论文
Molecular Cancer, 2022, 卷号: 21
作者:
Hua,Jinghan
;
Wang,Xiaolin
;
Ma,Liying
;
Li,Jingxin
;
Cao,Guozhen
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/12/22
CircVAPA
SCLC
Progression
miR-377-3p
miR-494-3p
IGF1R
AKT
BMS-536924
Endosulfan promotes cell migration via PTP4A3-mediated signaling pathways in HUVECs
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 192, 页码: 1-9
作者:
Li, Heng
;
Liu, Shiqi
;
Hu, Yumeng
;
Zhao, Bin
;
Sun, Yeqing
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/09/14
Endosulfan
Cell migration
PTP4A3
Signaling pathway
Endothelial cells
BOS-93, a novel bromophenol derivative, induces apoptosis and autophagy in human A549 lung cancer cells via PI3K/Akt/mTOR and MAPK signaling pathway
期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2019, 卷号: 17, 期号: 5, 页码: 3848-3858
作者:
Guo, Chuanlong
;
Wang, Lijun
;
Zhao, Yue
;
Jiang, Bo
;
Luo, Jiao
收藏
  |  
浏览/下载:119/0
  |  
提交时间:2019/08/28
bromophenol
apoptosis
autophagy
phosphoinositide 3-kinase
protein kinase B
mechanistic target of rapamycin signaling
reactive oxygen species
Carvedilol suppresses malignant proliferation of mammary epithelial cells through inhibition of the ROS-mediated PI3K/AKT signaling pathway
期刊论文
ONCOLOGY REPORTS, 2019, 卷号: 41, 期号: 2, 页码: 811-818
作者:
Ma, Zhongbing
;
Liu, Xingli
;
Zhang, Qiang
;
Yu, Zhigang
;
Gao, Dezong
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
carvedilol
cancer prevention
reactive oxygen species
phosphoinositide
3-kinase
protein kinase B signaling pathway
Dioscin attenuates high-fat diet-induced insulin resistance of adipose tissue through the IRS-1/PI3K/Akt signaling pathway
期刊论文
MOLECULAR MEDICINE REPORTS, 2019, 卷号: 19, 期号: 2, 页码: 1230-1237
作者:
Li, Haijuan
;
Yu, Lianzhi
;
Zhao, Changsheng
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
dioscin
insulin tolerance
high-fat diet
insulin receptor substrate 1
phosphoinositide 3-kinase
protein kinase B pathway
Downregulation of BAG-1 in T47D cells promotes resistance to tamoxifen via activation of the PI3K/Akt/mTOR signaling pathway
期刊论文
ONCOLOGY REPORTS, 2019, 卷号: 41, 期号: 3, 页码: 1901-1910
作者:
Lu, Su[1]
;
Du, Yiyi[2]
;
Cui, Fang[3]
;
Feng, Xinyi[4]
;
Ma, Yuanyuan[5]
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/24
Bcl-2-associated athanogene 1
breast cancer
tamoxifen resistance
phosphoinositide 3-kinase
protein kinase B
mammalian target of rapamycin pathway
rapamycin
Long non-coding RNA FER1L4 inhibits cell proliferation and metastasis through regulation of the PI3K/AKT signaling pathway in lung cancer cells
期刊论文
2019, 卷号: 20, 期号: 1, 页码: 182-190
作者:
Gao, Xuejin
;
Wang, Nianchang
;
Wu, Shanshan
;
Cui, Hongmei
;
An, Xue
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/01/03
Fer-1-like family member 4
proliferation
metastasis
phosphoinositide 3-kinase
protein kinase B signaling
lung cancer
Difuran-substituted quinoxalines as a novel class of PI3K alpha H1047R mutant inhibitors: Synthesis, biological evaluation and structure activity relationship
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 37-49
作者:
Zhang, Ning
;
Yu, Zhimei
;
Yang, Xiaohong
;
Zhou, Yan
;
Tang, Qing
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Proliferation
Anticancer drug
Phosphatidylinositol 3-kinase inhibitor
Apoptosis
Structure-activity relationship
Discovery of (S)-2-amino-N-(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide (CHMFL-PI3KD-317) as a potent and selective phosphoinositide 3-kinase delta (PI3K delta) inhibitor
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 页码: 831-846
作者:
Liang, Xiaofei
;
Li, Feng
;
Chen, Cheng
;
Jiang, Zongru
;
Wang, Aoli
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/10
PI3K delta
Kinase inhibitor
Acute myeloid leukemia
Structure-activity relationship
DCZ3301, a novel aryl-guanidino inhibitor, induces cell apoptosis and cell cycle arrest via suppressing the PI3K/AKT pathway in T-cell leukemia/lymphoma
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2018, 卷号: 50, 期号: 7, 页码: 643-650
作者:
Xiao, Wenqin
;
Li, Bo
;
Sun, Xi
;
Yu, Dandan
;
Xie, Yongsheng
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2019/01/08
DCZ3301
T-cell leukemia/lymphoma
apoptosis
cell cycle
PI3K/AKT
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