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中国医学科学院 北京... [3]
中南大学 [2]
暨南大学 [2]
南华大学 [1]
清华大学 [1]
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期刊论文 [14]
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2018 [1]
2017 [2]
2016 [2]
2015 [1]
2012 [2]
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Sall2 knockdown exacerbates palmitic acid induced dysfunction and apoptosis of pancreatic NIT-1 beta cells
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2018, 卷号: 104
作者:
Wang, Ye
;
Liu, Jie
;
Liu, Zheng
;
Chen, Jing
;
Hu, Xuemei
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/12/05
Spalt-like2
Beta cell
Lipotoxicity
Apoptosis
Antioxidant
Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells
期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:
Yang, Xin
;
Xu, Zhipeng
;
Zhang, Chunlan
;
Cai, Zixin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/12/03
A1c
glycated hemoglobin
AACE
American Association of Clinical Endocrinologists
ACC
acetyl-CoA carboxylase
ADA
American Diabetes Association
Akt/PKB
tyrosine kinase/protein kinase B
AMP
adenosine monophosphate
AMPK
adenosine monophosphate-activated protein
Ang II
angiotensin II
ATP
adenosine triphosphate
BAT
brown adipose tissue
CHOP
CEBP-homologous protein
CEBP
CCAAT enhancer binding protein
CoA
coenzyme A
DPP
Diabetes Prevention Program
EASD
European Association for the Study of Diabetes
eNOS
endothelial nitric oxide synthase
ER
endoplasmic reticulum
FDA
Food and Drug Administration
FFA
free fatty acid
FOXO1
forkhead box protein O1
G6P
glucose 6-phosphate
GDM
gestational diabetes mellitus
GIPR
glucose-dependent insulinotropic polypeptide receptor
GLP-1R
glucagon-like peptide-1 receptor
GLUT1
glucose transporter-1
GLUT4
glucose transporter type 4
GLUTs
glucose transporters
G6P
glucose 6-phosphate, glucose transporter-1
GPR40
G protein-coupled receptor 40
HbA1c
hemoglobin A1c
HGP
hepatic glucose production
HSL
hormone sensitive lipase
IL-6
interleukin 6
INS-1
insulinoma cells in rat
IR
insulin resistance
IRS-1
insulin receptor substrate 1
JNK
c-Jun. N-terminal kinase
Kir6.2
inwardly rectifying potassium/kalium channel
LDs
lipid droplets
LDL
low density lipoprotein
LV
left ventricular
MIN6 cells
mouse insulinoma cells
MAPK
mitogen-activated protein kinases
mPTP
mitochondrial permeability transition pore opening
mTOR
mammalian target of rapamycin
NADPH
nicotinamide adenine dinucleotide phosphate
NF-kappaB
nuclear factors-kappa B
NIT-1 cells
insulinoma cells
p70S6K
p70 ribosomal S6 kinase
PA
palmitic acid
NOS
NADPH oxidase
p38 MAPK
p38 mitogen-activated protein kinase
PA
palmitic acid
PCOS
polycystic ovary syndrome
PGC-1α
peroxisome proliferator-activated receptor-g coactivator-1α
PI3K
phosphatidylinositol 3-kinase
PKB
protein kinase B
PKC
protein kinase C
PPARα
peroxisome-proliferator activated receptor α
PTP
permeability transition pore
RCT
randomized controlled trial
RISK
reperfusion injury salvage kinase
ROS
reactive oxygen species
SERCA2
reticulum sarcoplasmic Ca2 +-ATPase
RISK
reperfusion injury salvage kinase
Smad3
mothers against decapentaplegic homolog 3
SRC-2
steroid receptor coactivator 2
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TGFβ1
transforming growth factor β1
TLR4
Toll-like receptor
TNF-α
tumor necrosis factor α
TR4
testicular receptor 4
UKPDS
United Kingdom Prospective Diabetes Study
VLDL
very low density lipoprotein
Metformin
Pancreatic β Cells
Heart failure
Insulin sensitizer
The PI3K/Akt1-FoxO1 Translocation Pathway Mediates EXf Effects on NIT-1 Cell Survival
期刊论文
2017, 卷号: 125, 期号: 10, 页码: 669-676
作者:
Hou, Guo-jiang
;
Li, Cai-na
;
Huan, Yi
;
Liu, Shuai-nan
;
Liu, Quan
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
EXf
GLP-1
FoxO1
NIT-1 cells
translocation
Enzymatic synthesis of 3-hydroxypropionic acid at high productivity by using free or immobilized cells of recombinant Escherichia coli
期刊论文
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 2016, 卷号: 129, 页码: 37-42
作者:
Yu, Shanshan
;
Yao, Peiyuan
;
Li, Jianjiong
;
Ren, Jie
;
Yuan, Jing
收藏
  |  
浏览/下载:91/0
  |  
提交时间:2017/03/21
Nitrilase
Immobilization
3-Hydroxypropionic acid
Hydrolysis
Enzyme catalysis
Display of Thermotoga maritima MSB8 nitrilase on the spore surface of Bacillus subtilis using out coat protein CotG as the fusion partner
期刊论文
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 2016, 卷号: 123, 期号: JAN, 页码: 73-80
作者:
Chen, Huayou
;
Chen, Zhi
;
Ni, Zhong
;
Tian, Rui
;
Zhang, Tianxi
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2016/04/22
Nitrilase
B. subtilis
Spore surface display
Enzyme immobilization
STAT1-mediated down-regulation of Bcl-2 expression is involved in IFN-gamma/TNF-alpha-induced apoptosis in NIT-1 cells.
期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 3, 页码: e0120921
作者:
Cao, Zhao-hui
;
Zheng, Quan-you
;
Li, Gui-qing
;
Hu, Xiao-bo
;
Feng, Shao-long
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/27
Apoptosis,Mitochondria,Confocal laser microscopy,Scanning confocal microscopy,Cytokines,Small interfering RNAs,Flow cytometry,Cell staining
NADPH oxidase 2 plays a critical role in dysfunction and apoptosis of pancreatic beta-cells induced by very low-density lipoprotein
期刊论文
2012, 卷号: 370, 期号: 1-2, 页码: 103-113
作者:
Jiao, Juan
;
Dou, Lin
;
Li, Miao
;
Lu, Yonggang
;
Guo, Han-Bang
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/01/13
VLDL
NIT-1 cells
Reactive oxygen species
NADPH oxidase 2
Apoptosis
NADPH Oxidase 2-derived Reactive Oxygen Species are Involved in Dysfunction and Apoptosis of Pancreatic beta-cells Induced by Low Density Lipoprotein
期刊论文
2012, 卷号: 30, 期号: 2, 页码: 439-449
作者:
Li, Miao
;
Dou, Lin
;
Jiao, Juan
;
Lu, Yonggang
;
Guo, Han-Bang
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/13
LDL
NIT-1 cells
NADPH oxidase 2
Reactive oxygen species
Over-expression of miR375 reduces glucose-induced insulin secretion in Nit-1 cells
期刊论文
Molecular Biology Reports, 2011, 卷号: 38, 期号: 5, 页码: 3061-3065
作者:
Xia, Hua-Qiang
;
Pan, Yi
;
Peng, Ju
;
Lu, Guang-Xiu*
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
Insulin secretion
MicroRNA375
Myotrophin (Mtpn)
Nit-1 cells
Effects of Oligo(3-hydroxyalkanoates) on the Viability and Insulin Secretion of Murine Beta Cells
期刊论文
2010, 2010
Yang, Xiao-Di
;
Zou, Xiang-Hui
;
Dai, Zhong-Wei
;
Luo, Rong-Cong
;
Wei, Chi-Ju
;
Chen, Guo-Qiang
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/06/15
PHB
oligomers
3-hydroxyalkanoates
diabetes
murine beta cell
insulin
MICROBIAL POLYHYDROXYALKANOATES
MECHANICAL-PROPERTIES
IN-VIVO
BIOCOMPATIBILITY
POLY(3-HYDROXYBUTYRATE-CO-3-HYDROXYHEXANOATE)
DEGRADATION
PARTICLES
OLIGOMERS
CHANNELS
ISLETS
Engineering, Biomedical
Materials Science, Biomaterials
Polymer Science
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