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CORC

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Zebrafish (Danio rerio) TR beta- and TTR-based electrochemical biosensors: Construction and application for the evaluation of thyroid-disrupting activity of bisphenols 期刊论文
ENVIRONMENTAL POLLUTION, 2023, 卷号: 330, 页码: 9
作者:  Li, Yuejiao;  Zhang, Zhenzhong;  Wang, Jun;  Shan, Yeqi;  Tian, Hua
收藏  |  浏览/下载：7/0  |  提交时间：2023/12/07
Discovery of a Novel Androgen Receptor Antagonist Manifesting Evidence to Disrupt the Dimerization of the Ligand-Binding Domain via Attenuating the Hydrogen-Bonding Network Between the Two Monomers 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64
作者:  Fu, Weitao;  Zhang, Minkui;  Liao, Jianing;  Tang, Qing;  Lei, Yixuan
收藏  |  浏览/下载：53/0  |  提交时间：2022/03/21
Binding and Activity of Tetrabromobisphenol A Mono-Ether Structural Analogs to Thyroid Hormone Transport Proteins and Receptors 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2020, 卷号: 128, 期号: 10, 页码: 1-10
作者:  Ren, Xiao-Min;  Yao, Linlin;  Xue, Qiao;  Shi, Jianbo;  Zhang, Qinghua
收藏  |  浏览/下载：34/0  |  提交时间：2021/09/14
Chemical Structure-Related Adipogenic Effects of Tetrabromobisphenol A and Its Analogues on 3T3-L1 Preadipocytes 期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2020, 卷号: 54, 期号: 10, 页码: 6262-6271
作者:  Liu, Qun S.;  Sun, Zhendong;  Ren, Xiaomin;  Ren, Zhihua;  Liu, Aifeng
收藏  |  浏览/下载：44/0  |  提交时间：2021/09/14
Identification and structural insight of an effective PPAR gamma modulator with improved therapeutic index for anti-diabetic drug discovery 期刊论文
CHEMICAL SCIENCE, 2020, 卷号: 11, 期号: 8, 页码: 2260-2268
作者:  Jiang, Haowen;  Zhou, X. Edward;  Shi, Jingjing;  Zhou, Zhi;  Zhao, Guanguan
收藏  |  浏览/下载：24/0  |  提交时间：2020/07/01
The molecular mechanism of the antagonistic activity of hydroxylated polybrominated biphenyl (OH-BB80) toward thyroid receptor beta 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2019, 卷号: 697, 页码: -
作者:  Zhang, Xiaofang;  Cui, Shixuan;  Pan, Liumeng;  Dong, Wenhua;  Ma, Mei
收藏  |  浏览/下载：13/0  |  提交时间：2020/09/10
Discovery of Novel Androgen Receptor Ligands by Structure-based Virtual Screening and Bioassays 期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 16, 期号: 6, 页码: 416-427
作者:  Hou, Tingjun;  Li, Dan;  Chang, Shan;  Xu, Lei;  Sun, Huiyong
收藏  |  浏览/下载：265/0  |  提交时间：2019/06/24
Characterization of the Aryl Hydrocarbon Receptor (AhR) Pathway in Anabas testudineus and Mechanistic Exploration of the Reduced Sensitivity of AhR2a 期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2019, 卷号: 53, 期号: 21, 页码: 12803-12811
作者:  Zhang, Wanglong;  Xie, Heidi Qunhui;  Li, Yunping;  Zou, Xianghui;  Xu, Li
收藏  |  浏览/下载：17/0  |  提交时间：2020/09/10
Communication between the Ligand-Binding Pocket and the Activation Function-2 Domain of Androgen Receptor Revealed by Molecular Dynamics Simulations 期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2019, 卷号: 59, 期号: 2, 页码: 842-857
作者:  Hou, Tingjun;  Li, Youyong;  Yu, Huidong;  Li, Dan;  Liu, Hui
收藏  |  浏览/下载：70/0  |  提交时间：2019/06/24
Evaluation of selected traditional Chinese medical extracts for bone mineral density maintenance: A mechanistic study. 期刊论文
Journal of traditional and complementary medicine, 2019, 卷号: 9, 期号: 3
作者:  Rebhun John F;  Du Qin;  Hood Molly;  Guo Hailing;  Glynn Kelly M
收藏  |  浏览/下载：45/0  |  提交时间：2019/12/05
Anti-inflammatory  BMD, bone mineral density  BSA, bovine serum albumin  Bmp4, bone morphogenic protein 4  CRE, cyclic adenosine monophosphate response element  CREB, cyclic adenosine monophosphate response element binding protein  DEXA, dual-energy X-ray absorptiometry  DMSO, Dimethyl sulfoxide  Drynaria fortunei  E2, estradiol  ER, estrogen receptor  ERE, estrogen response element  Epimedium brevicornu  Estrogenic  FBS, fetal bovine serum  Fsk, forskolin  Hprt, hypoxanthine-guanine phosphoribosyl-transferase  IL-1, interleukin 1  LBD, ligand binding domain  LBM, low bone mass  M-CSF, macrophage colony-stimulating factor  MAPK, mitogen activated protein kinase  NF-κβ, nuclear factor kappa beta  OP, osteoporosis  Osteoporosis  PTH, parathyroid hormone  PTHrp, PTH related peptide  RANKL, receptor activator of nuclear factor kappa beta ligand  RLU, relative luminescence unit  ROI, region of interest  Runx2, runt-related transcription factor 2  SFM, serum free media  TCM, traditional Chinese medicine  TNFα, tumor necrosis factor alpha  TRAP, tartrate-resistant acid phosphatase  UAS, upstream activating sequence  cAMP, cyclic adenosine monophosphate  qPCR, quantitative polymerase chain reaction  

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