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Structural basis for auxiliary subunit KCTD16 regulation of the GABA(B) receptor 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 卷号: 116, 期号: 17, 页码: 8370-8379
作者:  Zuo, Hao;  Glaaser, Ian
收藏  |  浏览/下载:19/0  |  提交时间:2020/07/01
Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells 期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:  Yang, Xin;  Xu, Zhipeng;  Zhang, Chunlan;  Cai, Zixin;  Zhang, Jingjing*
收藏  |  浏览/下载:38/0  |  提交时间:2019/12/03
A1c  glycated hemoglobin  AACE  American Association of Clinical Endocrinologists  ACC  acetyl-CoA carboxylase  ADA  American Diabetes Association  Akt/PKB  tyrosine kinase/protein kinase B  AMP  adenosine monophosphate  AMPK  adenosine monophosphate-activated protein  Ang II  angiotensin II  ATP  adenosine triphosphate  BAT  brown adipose tissue  CHOP  CEBP-homologous protein  CEBP  CCAAT enhancer binding protein  CoA  coenzyme A  DPP  Diabetes Prevention Program  EASD  European Association for the Study of Diabetes  eNOS  endothelial nitric oxide synthase  ER  endoplasmic reticulum  FDA  Food and Drug Administration  FFA  free fatty acid  FOXO1  forkhead box protein O1  G6P  glucose 6-phosphate  GDM  gestational diabetes mellitus  GIPR  glucose-dependent insulinotropic polypeptide receptor  GLP-1R  glucagon-like peptide-1 receptor  GLUT1  glucose transporter-1  GLUT4  glucose transporter type 4  GLUTs  glucose transporters  G6P  glucose 6-phosphate, glucose transporter-1  GPR40  G protein-coupled receptor 40  HbA1c  hemoglobin A1c  HGP  hepatic glucose production  HSL  hormone sensitive lipase  IL-6  interleukin 6  INS-1  insulinoma cells in rat  IR  insulin resistance  IRS-1  insulin receptor substrate 1  JNK  c-Jun. N-terminal kinase  Kir6.2  inwardly rectifying potassium/kalium channel  LDs  lipid droplets  LDL  low density lipoprotein  LV  left ventricular  MIN6 cells  mouse insulinoma cells  MAPK  mitogen-activated protein kinases  mPTP  mitochondrial permeability transition pore opening  mTOR  mammalian target of rapamycin  NADPH  nicotinamide adenine dinucleotide phosphate  NF-kappaB  nuclear factors-kappa B  NIT-1 cells  insulinoma cells  p70S6K  p70 ribosomal S6 kinase  PA  palmitic acid  NOS  NADPH oxidase  p38 MAPK  p38 mitogen-activated protein kinase  PA  palmitic acid  PCOS  polycystic ovary syndrome  PGC-1α  peroxisome proliferator-activated receptor-g coactivator-1α  PI3K  phosphatidylinositol 3-kinase  PKB  protein kinase B  PKC  protein kinase C  PPARα  peroxisome-proliferator activated receptor α  PTP  permeability transition pore  RCT  randomized controlled trial  RISK  reperfusion injury salvage kinase  ROS  reactive oxygen species  SERCA2  reticulum sarcoplasmic Ca2 +-ATPase  RISK  reperfusion injury salvage kinase  Smad3  mothers against decapentaplegic homolog 3  SRC-2  steroid receptor coactivator 2  T1DM  Type 1 diabetes mellitus  T2DM  Type 2 diabetes mellitus  TGFβ1  transforming growth factor β1  TLR4  Toll-like receptor  TNF-α  tumor necrosis factor α  TR4  testicular receptor 4  UKPDS  United Kingdom Prospective Diabetes Study  VLDL  very low density lipoprotein  Metformin  Pancreatic β Cells  Heart failure  Insulin sensitizer  
ABERRANT EXPRESSION OF THE PORE-FORMING K-ATP CHANNEL SUBUNIT Kir6.2 IN HIPPOCAMPAL REACTIVE ASTROCYTES IN THE 3xTg-AD MOUSE MODEL AND HUMAN ALZHEIMER'S DISEASE 期刊论文
2016, 卷号: 336, 页码: 81-101
作者:  Griffith, Chelsea M.;  Xie, Mi-Xin;  Qiu, Wen-Ying;  Sharp, Andrew A.;  Ma, Chao
收藏  |  浏览/下载:4/0  |  提交时间:2020/01/04
Tenidap, an agonist of the inwardly rectifying K+ channel Kir2.3, delays the onset of cortical epileptiform activity in a model of chronic temporal lobe epilepsy 期刊论文
NEUROLOGICAL RESEARCH, 2013, 卷号: 35, 期号: 6
作者:  Xu, Lan;  Hao, Yong;  Wu, Xunyi;  Yu, Peimin;  Zhu, Guoxing
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/19
The cytosolic GH loop regulates the phosphatidylinositol 4,5-bisphosphate-induced gating kinetics of Kir2 channels 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 卷号: 287, 期号: 50, 页码: 42278-42287
作者:  An HL;  Lv SQ(吕守芹);  Li JW;  Meng XY;  Zhan Y
收藏  |  浏览/下载:23/0  |  提交时间:2013/01/18
Genistein and tyrphostin AG556 inhibit inwardly-rectifying Kir2.1 channels expressed in HEK 293 cells via protein tyrosine kinase inhibition 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2011, 卷号: 1808, 期号: [db:dc_citation_issue], 页码: 1993-1999
作者:  Zhang, De-Yong;  Wu, Wei;  Deng, Xiu-Ling;  Lau, Chu-Pak;  Li, Gui-Rong
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/10
Effects of Kir2.1 gene transfection in cochlear hair cells and application of neurotrophic factors on survival and neurite growth of co-cultured cochlear spiral ganglion neurons 期刊论文
MOLECULAR AND CELLULAR NEUROSCIENCE, 2010, 卷号: 43, 期号: 3
作者:  Ruan, Qingwei;  Chen, Dong;  Wang, Zhengmin;  Chi, Fanglu;  He, Jinchun
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/19
Topological and Developmental Expression Gradients of Kir2.1, an Inward Rectifier K+ Channel, in Spiral Ganglion and Cochlear Hair Cells of Mouse Inner Ear 期刊论文
DEVELOPMENTAL NEUROSCIENCE, 2008, 卷号: 30, 期号: 6
作者:  Ruan, Qingwei;  Chen, Dong;  Wang, Zhengmin;  Chi, Fanglu;  Yin, Shankai
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/19
Ion channels mediate proton transduction in peripheral pain perception 期刊论文
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2004, 卷号: 31, 期号: 5, 页码: 393-397
Wu, LJ; Xu, TL(徐天乐)
收藏  |  浏览/下载:10/0  |  提交时间:2012/07/23
GM-CSP-induced Ca2+-activated non-voltage-dependent inwardly rectifying K+ channel in murine peritoneal exudate macrophages 期刊论文
Chinese Science Bulletin, 1997, 卷号: 42, 期号: 11, 页码: 947-952
Zhang XF; Feng MF; Wu CH; Zhou PA
收藏  |  浏览/下载:9/0  |  提交时间:2015/07/10


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