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复旦大学上海医学院 [3]
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西安交通大学 [1]
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期刊论文 [10]
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Structural basis for auxiliary subunit KCTD16 regulation of the GABA(B) receptor
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 卷号: 116, 期号: 17, 页码: 8370-8379
作者:
Zuo, Hao
;
Glaaser, Ian
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
GABA(B) receptor
KCTD
Principal and auxiliary subunits
crystal structure
Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells
期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:
Yang, Xin
;
Xu, Zhipeng
;
Zhang, Chunlan
;
Cai, Zixin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/12/03
A1c
glycated hemoglobin
AACE
American Association of Clinical Endocrinologists
ACC
acetyl-CoA carboxylase
ADA
American Diabetes Association
Akt/PKB
tyrosine kinase/protein kinase B
AMP
adenosine monophosphate
AMPK
adenosine monophosphate-activated protein
Ang II
angiotensin II
ATP
adenosine triphosphate
BAT
brown adipose tissue
CHOP
CEBP-homologous protein
CEBP
CCAAT enhancer binding protein
CoA
coenzyme A
DPP
Diabetes Prevention Program
EASD
European Association for the Study of Diabetes
eNOS
endothelial nitric oxide synthase
ER
endoplasmic reticulum
FDA
Food and Drug Administration
FFA
free fatty acid
FOXO1
forkhead box protein O1
G6P
glucose 6-phosphate
GDM
gestational diabetes mellitus
GIPR
glucose-dependent insulinotropic polypeptide receptor
GLP-1R
glucagon-like peptide-1 receptor
GLUT1
glucose transporter-1
GLUT4
glucose transporter type 4
GLUTs
glucose transporters
G6P
glucose 6-phosphate, glucose transporter-1
GPR40
G protein-coupled receptor 40
HbA1c
hemoglobin A1c
HGP
hepatic glucose production
HSL
hormone sensitive lipase
IL-6
interleukin 6
INS-1
insulinoma cells in rat
IR
insulin resistance
IRS-1
insulin receptor substrate 1
JNK
c-Jun. N-terminal kinase
Kir6.2
inwardly rectifying potassium/kalium channel
LDs
lipid droplets
LDL
low density lipoprotein
LV
left ventricular
MIN6 cells
mouse insulinoma cells
MAPK
mitogen-activated protein kinases
mPTP
mitochondrial permeability transition pore opening
mTOR
mammalian target of rapamycin
NADPH
nicotinamide adenine dinucleotide phosphate
NF-kappaB
nuclear factors-kappa B
NIT-1 cells
insulinoma cells
p70S6K
p70 ribosomal S6 kinase
PA
palmitic acid
NOS
NADPH oxidase
p38 MAPK
p38 mitogen-activated protein kinase
PA
palmitic acid
PCOS
polycystic ovary syndrome
PGC-1α
peroxisome proliferator-activated receptor-g coactivator-1α
PI3K
phosphatidylinositol 3-kinase
PKB
protein kinase B
PKC
protein kinase C
PPARα
peroxisome-proliferator activated receptor α
PTP
permeability transition pore
RCT
randomized controlled trial
RISK
reperfusion injury salvage kinase
ROS
reactive oxygen species
SERCA2
reticulum sarcoplasmic Ca2 +-ATPase
RISK
reperfusion injury salvage kinase
Smad3
mothers against decapentaplegic homolog 3
SRC-2
steroid receptor coactivator 2
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TGFβ1
transforming growth factor β1
TLR4
Toll-like receptor
TNF-α
tumor necrosis factor α
TR4
testicular receptor 4
UKPDS
United Kingdom Prospective Diabetes Study
VLDL
very low density lipoprotein
Metformin
Pancreatic β Cells
Heart failure
Insulin sensitizer
ABERRANT EXPRESSION OF THE PORE-FORMING K-ATP CHANNEL SUBUNIT Kir6.2 IN HIPPOCAMPAL REACTIVE ASTROCYTES IN THE 3xTg-AD MOUSE MODEL AND HUMAN ALZHEIMER'S DISEASE
期刊论文
2016, 卷号: 336, 页码: 81-101
作者:
Griffith, Chelsea M.
;
Xie, Mi-Xin
;
Qiu, Wen-Ying
;
Sharp, Andrew A.
;
Ma, Chao
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/04
astrogliosis
CA1
GFAP
inwardly rectifying potassium channels
Kir6.1
glutamine synthetase
Tenidap, an agonist of the inwardly rectifying K+ channel Kir2.3, delays the onset of cortical epileptiform activity in a model of chronic temporal lobe epilepsy
期刊论文
NEUROLOGICAL RESEARCH, 2013, 卷号: 35, 期号: 6
作者:
Xu, Lan
;
Hao, Yong
;
Wu, Xunyi
;
Yu, Peimin
;
Zhu, Guoxing
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/19
Inwardly rectifying K+ channel
Kir2.3
Temporal lobe epilepsy
Tenidap
The cytosolic GH loop regulates the phosphatidylinositol 4,5-bisphosphate-induced gating kinetics of Kir2 channels
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 卷号: 287, 期号: 50, 页码: 42278-42287
作者:
An HL
;
Lv SQ(吕守芹)
;
Li JW
;
Meng XY
;
Zhan Y
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2013/01/18
Rectifier K+ Channels
Beta-Gamma-Subunits
Potassium Channels
Crystal-Structure
G-Proteins
Structural Basis
Voltage-Sensor
PIP2
Activation
Dynamics
Genistein and tyrphostin AG556 inhibit inwardly-rectifying Kir2.1 channels expressed in HEK 293 cells via protein tyrosine kinase inhibition
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2011, 卷号: 1808, 期号: [db:dc_citation_issue], 页码: 1993-1999
作者:
Zhang, De-Yong
;
Wu, Wei
;
Deng, Xiu-Ling
;
Lau, Chu-Pak
;
Li, Gui-Rong
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/10
Protein tyrosine kinase
Kir2.1
Inward rectifier K(+) channel
Epidermal growth factor receptor kinase
Effects of Kir2.1 gene transfection in cochlear hair cells and application of neurotrophic factors on survival and neurite growth of co-cultured cochlear spiral ganglion neurons
期刊论文
MOLECULAR AND CELLULAR NEUROSCIENCE, 2010, 卷号: 43, 期号: 3
作者:
Ruan, Qingwei
;
Chen, Dong
;
Wang, Zhengmin
;
Chi, Fanglu
;
He, Jinchun
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/19
Spontaneous activity
Inwardly rectifying K plus Channel kir2.1 transfection
Hair cells
Spiral ganglion neurons
Organ of corti
Topological and Developmental Expression Gradients of Kir2.1, an Inward Rectifier K+ Channel, in Spiral Ganglion and Cochlear Hair Cells of Mouse Inner Ear
期刊论文
DEVELOPMENTAL NEUROSCIENCE, 2008, 卷号: 30, 期号: 6
作者:
Ruan, Qingwei
;
Chen, Dong
;
Wang, Zhengmin
;
Chi, Fanglu
;
Yin, Shankai
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/19
Inwardly rectifying K+ channel Kir2.1
Hair cells
Spiral ganglion neurons
Cochlea
Combined immunofluorescence and in situ hybridization
Inner ear
Ion channels mediate proton transduction in peripheral pain perception
期刊论文
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2004, 卷号: 31, 期号: 5, 页码: 393-397
Wu, LJ
;
Xu, TL(徐天乐)
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2012/07/23
pain
tissue acidosis
ion channels
CAPSAICIN RECEPTOR
P2X RECEPTORS
MICE LACKING
K+ CHANNEL
NEURONS
RAT
NOCICEPTION
STIMULI
FAMILY
PH
GM-CSP-induced Ca2+-activated non-voltage-dependent inwardly rectifying K+ channel in murine peritoneal exudate macrophages
期刊论文
Chinese Science Bulletin, 1997, 卷号: 42, 期号: 11, 页码: 947-952
Zhang XF
;
Feng MF
;
Wu CH
;
Zhou PA
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2015/07/10
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