×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海生物化学与细胞生... [7]
中南大学 [6]
上海药物研究所 [4]
上海中医药大学 [4]
西安交通大学 [3]
南华大学 [2]
更多...
内容类型
期刊论文 [44]
学位论文 [4]
发表日期
2019 [2]
2018 [6]
2017 [4]
2016 [8]
2015 [4]
2014 [4]
更多...
学科主题
Cell Biolo... [2]
Oncology [2]
Biochemist... [1]
Biochemist... [1]
Chemistry,... [1]
生物化学与分子生物学 [1]
更多...
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共48条,第1-10条
帮助
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
PYCR1 interference inhibits cell growth and survival via c-Jun N-terminal kinase/insulin receptor substrate 1 (JNK/IRS1) pathway in hepatocellular cancer
期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2019, 卷号: 17, 期号: 1
作者:
Wang, Jiening
;
Zhuang, Juhua
;
Song, Yanan
;
Xia, Wei
;
Ye, Ying
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/05
PYCR1
Hepatocellular carcinoma
JNK
IRS1
Insulin resistance
Dioscin attenuates high-fat diet-induced insulin resistance of adipose tissue through the IRS-1/PI3K/Akt signaling pathway
期刊论文
MOLECULAR MEDICINE REPORTS, 2019, 卷号: 19, 期号: 2, 页码: 1230-1237
作者:
Li, Haijuan
;
Yu, Lianzhi
;
Zhao, Changsheng
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
dioscin
insulin tolerance
high-fat diet
insulin receptor substrate 1
phosphoinositide 3-kinase
protein kinase B pathway
Cd2-associated protein contributes to hepatitis c, virus propagation and steatosis by disrupting insulin signaling
期刊论文
Hepatology, 2018, 卷号: 68, 期号: 5, 页码: 1710-1725
作者:
Zhang, Huixia
;
Zhang, Chao
;
Tang, Hong
;
Gao, Shanshan
;
Sun, Fang
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2019/05/08
Anti-diabetic Effect of Punica granatum Flower Polyphenols Extract in Type 2 Diabetic Rats: Activation of Akt/GSK-3 beta and Inhibition of IRE1 alpha-XBP1 Pathways
期刊论文
FRONTIERS IN ENDOCRINOLOGY, 2018, 卷号: 9
作者:
Tang, Dan
;
Liu, Liu
;
Ajiakber, Dildar
;
Ye, Jianping
;
Xu, Jianjun
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2019/01/08
type 2 diabetes mellitus
Punica granatum L. flower
anti-diabetic herb
oral glucose tolerance test
endoplasmic reticulum stress
insulin resistance
MicroRNA-1225-5p behaves as a tumor suppressor in human glioblastoma via targeting of IRS1
期刊论文
ONCOTARGETS AND THERAPY, 2018, 卷号: 11
作者:
Chen, Zhuo
;
Li, Dongyuan
;
Chi, Guonan
;
Jin, Xingyi
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/05
microRNA
microRNA-1225-5p
glioblastoma
insulin receptor substrate 1
prognosis
Huangqi (astragalus) decoction ameliorates diabetic nephropathy via IRS1-PI3K-GLUT signaling pathway
期刊论文
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2018, 卷号: 10, 期号: 8
作者:
Chen, Xia
;
Wang, Hao
;
Jiang, Minqian
;
Zhao, Jie
;
Fan, Chunling
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
Astragalus
insulin receptor substrate1
phosphatidylinositol 3 kinase
glucose transporter
db/db mice
diabetic nephropathy
Th-POK regulates mammary gland lactation through mTOR-SREBP pathway
期刊论文
PLOS GENETICS, 2018, 卷号: 14, 期号: 2, 页码: -
作者:
Zhang, Rui
;
Ma, Huimin
;
Gao, Yuan
;
Wu, Yanjun
;
Qiao, Yuemei
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2019/04/28
Milk Lipid Formation
Lineage Commitment
Secretory Differentiation
Improves Hyperlipidemia
Xanthine-oxidoreductase
Transcription Factors
Cell Differentiation
Positive Selection
Insulin-resistance
Complex 1
Huangqi (astragalus) decoction ameliorates diabetic nephropathy via IRS1-PI3K-GLUT signaling pathway
期刊论文
American journal of translational research, 2018, 卷号: 10, 页码: 2491-2501
作者:
Chen Xia[1]
;
Wang Hao[2]
;
Jiang Minqian[3]
;
Zhao Jie[4]
;
Fan Chunling[5]
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/04/22
Astragalus
db/db mice
diabetic nephropathy
glucose transporter
insulin receptor substrate1
phosphatidylinositol 3 kinase
Anti-diabetic effect of three new norditerpenoid alkaloids in vitro and potential mechanism via PI3K/Akt signaling pathway
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2017, 卷号: 87, 期号: 3, 页码: 145-152
作者:
Tang, D (Tang, Dan)
;
Chen, QB (Chen, Qi-Bin)
;
Xin, XL (Xin, Xue-Lei)
;
Aisa, HA (Aisa, Haji-Akber)
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2017/04/05
Diabetes
Norditerpenoid alkaloids
Anti-diabetic activity
Glucose metabolism
Protein tyrosine phosphatase 1B
PI3K/Akt signaling pathway
Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells
期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:
Yang, Xin
;
Xu, Zhipeng
;
Zhang, Chunlan
;
Cai, Zixin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/12/03
A1c
glycated hemoglobin
AACE
American Association of Clinical Endocrinologists
ACC
acetyl-CoA carboxylase
ADA
American Diabetes Association
Akt/PKB
tyrosine kinase/protein kinase B
AMP
adenosine monophosphate
AMPK
adenosine monophosphate-activated protein
Ang II
angiotensin II
ATP
adenosine triphosphate
BAT
brown adipose tissue
CHOP
CEBP-homologous protein
CEBP
CCAAT enhancer binding protein
CoA
coenzyme A
DPP
Diabetes Prevention Program
EASD
European Association for the Study of Diabetes
eNOS
endothelial nitric oxide synthase
ER
endoplasmic reticulum
FDA
Food and Drug Administration
FFA
free fatty acid
FOXO1
forkhead box protein O1
G6P
glucose 6-phosphate
GDM
gestational diabetes mellitus
GIPR
glucose-dependent insulinotropic polypeptide receptor
GLP-1R
glucagon-like peptide-1 receptor
GLUT1
glucose transporter-1
GLUT4
glucose transporter type 4
GLUTs
glucose transporters
G6P
glucose 6-phosphate, glucose transporter-1
GPR40
G protein-coupled receptor 40
HbA1c
hemoglobin A1c
HGP
hepatic glucose production
HSL
hormone sensitive lipase
IL-6
interleukin 6
INS-1
insulinoma cells in rat
IR
insulin resistance
IRS-1
insulin receptor substrate 1
JNK
c-Jun. N-terminal kinase
Kir6.2
inwardly rectifying potassium/kalium channel
LDs
lipid droplets
LDL
low density lipoprotein
LV
left ventricular
MIN6 cells
mouse insulinoma cells
MAPK
mitogen-activated protein kinases
mPTP
mitochondrial permeability transition pore opening
mTOR
mammalian target of rapamycin
NADPH
nicotinamide adenine dinucleotide phosphate
NF-kappaB
nuclear factors-kappa B
NIT-1 cells
insulinoma cells
p70S6K
p70 ribosomal S6 kinase
PA
palmitic acid
NOS
NADPH oxidase
p38 MAPK
p38 mitogen-activated protein kinase
PA
palmitic acid
PCOS
polycystic ovary syndrome
PGC-1α
peroxisome proliferator-activated receptor-g coactivator-1α
PI3K
phosphatidylinositol 3-kinase
PKB
protein kinase B
PKC
protein kinase C
PPARα
peroxisome-proliferator activated receptor α
PTP
permeability transition pore
RCT
randomized controlled trial
RISK
reperfusion injury salvage kinase
ROS
reactive oxygen species
SERCA2
reticulum sarcoplasmic Ca2 +-ATPase
RISK
reperfusion injury salvage kinase
Smad3
mothers against decapentaplegic homolog 3
SRC-2
steroid receptor coactivator 2
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TGFβ1
transforming growth factor β1
TLR4
Toll-like receptor
TNF-α
tumor necrosis factor α
TR4
testicular receptor 4
UKPDS
United Kingdom Prospective Diabetes Study
VLDL
very low density lipoprotein
Metformin
Pancreatic β Cells
Heart failure
Insulin sensitizer
©版权所有 ©2017 CSpace - Powered by
CSpace