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Optimized dose selective HDAC inhibitor tucidinostat overcomes anti-PD-L1 antibody resistance in experimental solid tumors
期刊论文
BMC Medicine, 2022, 卷号: 20, 期号: 1
作者:
Zhang,Pei
;
Du,Yang
;
Bai,Hua
;
Wang,Zhijie
;
Duan,Jianchun
收藏
  |  
浏览/下载:123/0
  |  
提交时间:2022/11/21
Tucidinostat
Tumor microenvironment
PD-L1
CCL5
Solid tumor
A dynamic fluorescence probed glycolysis suppression process in HeLa cells treated with trichostatin A
期刊论文
ANALYST, 2022
作者:
Zhang, Fengqiu
;
Shao, Changsheng
;
Wu, Yahui
;
Zhao, Wei
;
Jing, Xumiao
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2022/12/22
A near-infrared fluorescent probe was used to evaluate the role of histone deacetylase in pulmonary fibrosis cells and mice
期刊论文
SENSORS AND ACTUATORS B-CHEMICAL, 2022, 卷号: 366, 页码: 8
作者:
Wei, Yinghui
;
Hou, Junjun
;
Lu, Pengpeng
;
Fu, Lili
;
Wang, Xiaoyan
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/07/26
Fluorescent probe
Near-infrared
Histone deacetylases
Idiopathic pulmonary fibrosis
Fluorescence imaging
Vanguard is a Glucose Deprivation-Responsive Long Non-Coding RNA Essential for Chromatin Remodeling-Reliant DNA Repair
期刊论文
ADVANCED SCIENCE, 2022
作者:
Zhang, Ben
;
Thorne, Rick Francis
;
Zhang, Pengfei
;
Wu, Mian
;
Liu, Lianxin
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2022/12/23
genomic stability
HMGB1
long non-coding RNAs
PARP inhibitors
Vanguard
FK228 potentiates topotecan activity against small cell lung cancer cells via induction of SLFN11
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021
作者:
Yin, Yan-ping
;
Ma, Li-ying
;
Cao, Guo-zhen
;
Hua, Jing-han
;
Lv, Xiao-tong
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2022/01/10
small cell lung cancer
topotecan
DNA damage response
FK228
SLFN11
methylation
epigenetic modulation
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
Discovery of selective HDAC/BRD4 dual inhibitors as epigenetic probes
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 20
作者:
Chen, Jingjing
;
Li, Yalei
;
Zhang, Jie
;
Zhang, Minmin
;
Wei, Aihuan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
HDAC
BRD4
Selective dual inhibitors
Anticancer
S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and Lipogenesis
期刊论文
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 2021, 卷号: 11, 期号: 3, 页码: 697-724
作者:
Zhang, Linqiang
;
Zhang, Zhiguo
;
Li, Chengbin
;
Zhu, Tingting
;
Gao, Jing
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/05/24
NAFLD
S100A11
FOXO1
Autophagy
Lipid Metabolism
The design of a novel near-infrared fluorescent HDAC inhibitor and image of tumor cells
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 17, 页码: 5
作者:
Huang, Ying
;
Ru, Hong-bo
;
Bao, Bin
;
Yu, Jia-hui
;
Li, Jia
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/24
HDAC
Probe
NIR
Tumor imaging
Development of a Novel Histone Deacetylase-Targeted Near-Infrared Probe for Hepatocellular Carcinoma Imaging and Fluorescence Image-Guided Surgery
期刊论文
MOLECULAR IMAGING AND BIOLOGY, 2020, 卷号: 22, 期号: 3, 页码: 476-485
作者:
Tang, Chu
;
Du, Yang
;
Liang, Qian
;
Cheng, Zhen
;
Tian, Jie
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/06/22
Specific targeting probe
Histone deacetylase
Fluorescence imaging
Hepatocellular carcinoma
Fluorescence image-guided surgery
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