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An aggregation-induced emission fluorescence probe for evaluating the effect of CYP450 changes under tumor chemotherapy
期刊论文
TALANTA, 2022, 卷号: 239, 页码: 9
作者:
Lu, Pengpeng
;
Huang, Yan
;
Zhang, Caiyun
;
Fu, Lili
;
Wang, Xiaoyan
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/07/04
Cytochrome P450
Fluorescence imaging
Chemotherapy
Liver cancer
Antifungal azoles and azole resistance in the environment: current status and future perspectives-a review
期刊论文
REVIEWS IN ENVIRONMENTAL SCIENCE AND BIO-TECHNOLOGY, 2021, 页码: 31
作者:
Assress, Hailemariam Abrha
;
Selvarajan, Ramganesh
;
Nyoni, Hlengilizwe
;
Mamba, Bhekie B.
;
Msagati, Titus A. M.
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/11/16
Occurrence
Azole antifungal drugs
Azole resistance
Future perspectives
Fungi
Environment
Evaluate the inhibition of cytochrome P450 1A1 for enhancing breast cancer chemotherapy with a turn-on fluorescent probe
期刊论文
SENSORS AND ACTUATORS B-CHEMICAL, 2021, 卷号: 344, 页码: 8
作者:
Huang, Yan
;
Yu, Lei
;
Lu, Pengpeng
;
Wei, Yinghui
;
Wang, Xiaoyan
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2021/10/21
Fluorescent probe
Chemotherapy
Breast cancer
Fluorescence imaging
Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity
期刊论文
XENOBIOTICA, 2021, 页码: 13
作者:
Sun, Dongxue
;
Gao, Xiaoxia
;
Wang, Qiao
;
Krausz, Kristopher W.
;
Fang, Zhongze
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2021/11/04
CYP
podophyllotoxin metabolism
liver microsomes
recombinant drug-metabolizing enzymes
hepatic and intestinal toxicity
Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439
期刊论文
ACS INFECTIOUS DISEASES, 2021, 卷号: 7, 期号: 7, 页码: 1885-1893
作者:
Shackleford, David M.
;
Chiu, Francis C. K.
;
Katneni, Kasiram
;
Blundell, Scott
;
McLaren, Jenna
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  |  
浏览/下载:59/0
  |  
提交时间:2021/11/04
OZ439 (artefenomel)
malaria
metabolite identification
cytochrome P450 metabolism
cytochrome P450 inhibition
time-dependent inhibition
The inhibitory effect of 225 frequently-used traditional Chinese medicines for CYP3A4 metabolic enzyme by isoform-specific probe
期刊论文
FITOTERAPIA, 2021, 卷号: 152, 页码: 5
作者:
Wei, Wenlong
;
Li, Zhenwei
;
Li, Hao-jv
;
An, Yaling
;
Qu, Hua
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/08/17
Inhibitory effect
Frequently-used traditional Chinese medicines
Isoform-specific probe
Pharmacokinetic Drug-drug Interaction of Antibiotics Used in Sepsis Care in China
期刊论文
CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 1, 页码: 5-23
作者:
Yu, Xuan
;
Chu, Zixuan
;
Li, Jian
;
He, Rongrong
;
Wang, Yaya
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/05/24
Pharmacokinetics
drug-drug interaction
antibiotic
sepsis
transporter
enzyme
Drug interaction of ningetinib and gefitinib involving CYP1A1 and efflux transporters in non-small cell lung cancer patients
期刊论文
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2020, 页码: 13
作者:
Liu, Lu
;
Wang, Qian
;
Xie, Cen
;
Xi, Ning
;
Guo, Zitao
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2020/12/24
drug–
drug interaction
gefitinib
ningetinib
transporters
TCDD-induced antagonism of MEHP-mediated migration and invasion partly involves aryl hydrocarbon receptor in MCF7 breast cancer cells
期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2020, 卷号: 398, 页码: 1-10
作者:
Shan, Anqi
;
Leng, Ling
;
Li, Jing
;
Luo, Xiu-mei
;
Fan, Ya-jiao
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/09/14
Coexposure
Antagonism
AhR
Migration
Invasion
Alflutinib (AST2818), primarily metabolized by CYP3A4, is a potent CYP3A4 inducer
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Liu, Xiao-yun
;
Guo, Zi-tao
;
Chen, Zhen-dong
;
Zhang, Yi-fan
;
Zhou, Jia-lan
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2020/07/01
alflutinib
AST5902
metabolism
enzyme induction
drug-drug interaction
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