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期刊论文 [42]
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A near-infrared fluorescent probe was used to evaluate the role of histone deacetylase in pulmonary fibrosis cells and mice
期刊论文
SENSORS AND ACTUATORS B-CHEMICAL, 2022, 卷号: 366, 页码: 8
作者:
Wei, Yinghui
;
Hou, Junjun
;
Lu, Pengpeng
;
Fu, Lili
;
Wang, Xiaoyan
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/07/26
Fluorescent probe
Near-infrared
Histone deacetylases
Idiopathic pulmonary fibrosis
Fluorescence imaging
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
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  |  
浏览/下载:95/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
Cycloastragenol upregulates SIRT1 expression, attenuates apoptosis and suppresses neuroinflammation after brain ischemia
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Li, Man
;
Li, Shi-chun
;
Dou, Bao-kai
;
Zou, Ying-xiang
;
Han, Hao-zhen
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/01
cycloastragenol
SIRT1
apoptosis
neuroinflammation
cerebral ischemia
Flow-enhanced priming of hESCs through H2B acetylation and chromatin decondensation
期刊论文
STEM CELL RESEARCH & THERAPY, 2019, 卷号: 10, 期号: 1, 页码: 16
作者:
Wang JW(王家文)
;
Wu Y(武亿)
;
Zhang X(张潇)
;
Zhang F(张帆)
;
Lv DY(吕东媛)
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  |  
浏览/下载:23/0
  |  
提交时间:2020/03/11
Embryonic stem cell
Fluid shear mechanomics
Nuclear spreading
Histone acetylation
Chromatin decondensation
Discovery of trisubstituted nicotinonitrile derivatives as novel human GCN5 inhibitors through AlphaScreen-based high throughput screening
期刊论文
RSC ADVANCES, 2019, 卷号: 9, 期号: 9, 页码: 4917-4924
作者:
Tao, Hongru
;
Wang, Jun
;
Lu, Wenchao
;
Zhang, Rukang
;
Xie, Yiqian
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  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 20, 页码: 5397-5407
作者:
Lu, Wenchao
;
Xiong, Huan
;
Chen, Yu
;
Wang, Chen
;
Zhang, Hao
收藏
  |  
浏览/下载:140/0
  |  
提交时间:2019/01/08
Drug discovery
Epigenetics
Histone acetyltransferase
P300/CBP
Discovery of 1,8-acridinedione derivatives as novel GCN5 inhibitors via high throughput screening
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 740-751
作者:
Xiong, Huan
;
Han, Jie
;
Wang, Jun
;
Lu, Wenchao
;
Wang, Chen
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
Epigenetics
Histone acetyltransferase
GCN5
High throughput screening
1,8-Acridinedione derivative
Hyper-acetylation contributes to the sensitivity of chemo-resistant prostate cancer cells to histone deacetylase inhibitor Trichostatin A
期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2018, 卷号: 22, 期号: 3, 页码: 1909-1922
作者:
Xu, Qingqing
;
Liu, Xiaofei
;
Zhu, Shiqin
;
Hu, Xuelei
;
Niu, Huanmin
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
chemo-resistant mCRPC
HDAC inhibitors
apoptosis
hyper-acetylation
acetyl-CoA
ER stress
Steroidogenic factor-1 hypermethylation in maternal rat blood could serve as a biomarker for intrauterine growth retardation
期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 56, 页码: 96139-96153
作者:
Wu, Dong-Mei
;
Ma, Liang-Peng
;
Song, Gui-Li
;
Long, Yong
;
Liu, Han-Xiao
收藏
  |  
浏览/下载:149/0
  |  
提交时间:2019/07/03
steroidogenic factor-1 (SF-1)
DNA methylation
intrauterine growth retardation (IUGR)
clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas9)
biomarker
Comparative Proteomic Analysis of Lysine Acetylation in Fish CIK Cells Infected with Aquareovirus
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 卷号: 18, 期号: 11, 页码: 21
作者:
Guo, Hong
;
Zhang, Jie
;
Wang, Yaping
;
Bu, Chen
;
Zhou, Yanyan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/07/03
comparative proteomics
Ctenopharyngodon idella kidney cells
aquareovirus infection
lysine acetylation
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