CORC

浏览/检索结果: 共34条,第1-10条 帮助

限定条件                
已选(0)清除 条数/页:   排序方式:
Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells 期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:  Yang, Xin;  Xu, Zhipeng;  Zhang, Chunlan;  Cai, Zixin;  Zhang, Jingjing*
收藏  |  浏览/下载:38/0  |  提交时间:2019/12/03
A1c  glycated hemoglobin  AACE  American Association of Clinical Endocrinologists  ACC  acetyl-CoA carboxylase  ADA  American Diabetes Association  Akt/PKB  tyrosine kinase/protein kinase B  AMP  adenosine monophosphate  AMPK  adenosine monophosphate-activated protein  Ang II  angiotensin II  ATP  adenosine triphosphate  BAT  brown adipose tissue  CHOP  CEBP-homologous protein  CEBP  CCAAT enhancer binding protein  CoA  coenzyme A  DPP  Diabetes Prevention Program  EASD  European Association for the Study of Diabetes  eNOS  endothelial nitric oxide synthase  ER  endoplasmic reticulum  FDA  Food and Drug Administration  FFA  free fatty acid  FOXO1  forkhead box protein O1  G6P  glucose 6-phosphate  GDM  gestational diabetes mellitus  GIPR  glucose-dependent insulinotropic polypeptide receptor  GLP-1R  glucagon-like peptide-1 receptor  GLUT1  glucose transporter-1  GLUT4  glucose transporter type 4  GLUTs  glucose transporters  G6P  glucose 6-phosphate, glucose transporter-1  GPR40  G protein-coupled receptor 40  HbA1c  hemoglobin A1c  HGP  hepatic glucose production  HSL  hormone sensitive lipase  IL-6  interleukin 6  INS-1  insulinoma cells in rat  IR  insulin resistance  IRS-1  insulin receptor substrate 1  JNK  c-Jun. N-terminal kinase  Kir6.2  inwardly rectifying potassium/kalium channel  LDs  lipid droplets  LDL  low density lipoprotein  LV  left ventricular  MIN6 cells  mouse insulinoma cells  MAPK  mitogen-activated protein kinases  mPTP  mitochondrial permeability transition pore opening  mTOR  mammalian target of rapamycin  NADPH  nicotinamide adenine dinucleotide phosphate  NF-kappaB  nuclear factors-kappa B  NIT-1 cells  insulinoma cells  p70S6K  p70 ribosomal S6 kinase  PA  palmitic acid  NOS  NADPH oxidase  p38 MAPK  p38 mitogen-activated protein kinase  PA  palmitic acid  PCOS  polycystic ovary syndrome  PGC-1α  peroxisome proliferator-activated receptor-g coactivator-1α  PI3K  phosphatidylinositol 3-kinase  PKB  protein kinase B  PKC  protein kinase C  PPARα  peroxisome-proliferator activated receptor α  PTP  permeability transition pore  RCT  randomized controlled trial  RISK  reperfusion injury salvage kinase  ROS  reactive oxygen species  SERCA2  reticulum sarcoplasmic Ca2 +-ATPase  RISK  reperfusion injury salvage kinase  Smad3  mothers against decapentaplegic homolog 3  SRC-2  steroid receptor coactivator 2  T1DM  Type 1 diabetes mellitus  T2DM  Type 2 diabetes mellitus  TGFβ1  transforming growth factor β1  TLR4  Toll-like receptor  TNF-α  tumor necrosis factor α  TR4  testicular receptor 4  UKPDS  United Kingdom Prospective Diabetes Study  VLDL  very low density lipoprotein  Metformin  Pancreatic β Cells  Heart failure  Insulin sensitizer  
Stauntoside B inhibits macrophage activation by inhibiting NF-κB and ERK MAPK signalling 期刊论文
Pharmacological Research, 2016, 卷号: 111, 期号: Volume 111, 页码: 303-315
作者:  Liu, Jianxin;  Tang, Jinshan;  Zuo, Yihan;  Yu, Yang;  Luo, Pei
收藏  |  浏览/下载:19/0  |  提交时间:2019/12/03
NO  nitric oxide  PGE2  prostaglandin E2  NSAIDs  non-steroidal anti-inflammatory drugs  qRT-PCR  quantitative real-time polymerase chain reaction  LPS  lipopolysaccharide  IFN-γ  interferon γ  G-CSF  granulocyte colony stimulating factor  TNF-α  tumor necrosis factor-α  IL-1β  interleukin-1β  IL-6  interleukin-6  MCP-1  monocyte chemoattractant protein-1  NF-κB  Nuclear factor-κB  IκB  inhibitory protein  IKK  IκB kinase  RPS3  ribosomal protein S3  iNOS  inducible nitric oxide synthase  COX-2  cyclooxygenase-2  PGESs  prostaglandin E2 synthases  mPGES-1  microsomal prostaglandin synthetase-1  mPGES-2  microsomal prostaglandin E synthase-2  cPGES  cytosolic prostaglandin E synthase  MAPK  mitogen-activated protein kinases  ERK  extracellular signal-regulated kinase  JNK  c- Jun N-terminal kinase  PGI2  prostacyclin I2  PGD2  prostaglandin D2  PGF2α  prostaglandin F2α  TXA2  thromboxane A2  Stauntoside B (PubChem CID: 101010462)  Stauntoside B  Cynanchi stauntonii  Lipopolysaccharide  Anti-inflammatory activity  NF-κB  MAPK  
Changes of regulatory T cells, transforming growth factor-beta and interleukin-10 in patients with type 1 diabetes mellitus: A systematic review and meta-analysis 期刊论文
Clinical Immunology, 2016, 卷号: 170, 页码: 61-69
作者:  Qiao, Yong-chao;  Shen, Jian;  Hong, Xue-zhi;  Liang, Ling;  Bo, Chao-sheng
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/03
Interleukin-1beta Plays a Pivotal Role via the PI3K/Akt/mTOR Signaling Pathway in the Chronicity of Mesial Temporal Lobe Epilepsy. 期刊论文
NEUROIMMUNOMODULATION, 2016, 卷号: 23, 期号: 5-6, 页码: 332-344
作者:  Xiao, Zhaohua;  Peng, Jing;  Gan, Na;  Arafat, Ahmed;  Yin, Fei*
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/03
Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice 期刊论文
Gastroenterology, 2016, 卷号: 151, 期号: 1, 页码: 152-164.e11
作者:  Bergstrom, Kirk;  Liu, Xiaowei;  Zhao, Yiming;  Gao, Nan;  Wu, Qian
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/03
The effect of HMGB1 on sub-toxic chlorpyrifos exposure-induced neuroinflammation in amygdala of neonatal rats 期刊论文
Toxicology, 2015, 卷号: 338, 页码: 95-103
作者:  Tian, Jing;  Dai, Hongmei;  Deng, Yuanying;  Zhang, Jie;  Li, Ying
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/03
Overexpression of circadian clock protein cryptochrome (CRY) 1 alleviates sleep deprivation-induced vascular inflammation in a mouse model 期刊论文
Immunology Letters, 2015, 卷号: 163, 期号: 1, 页码: 76-83
作者:  Qin, Bing;  Deng, Yunlong*
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/03
Association of IL-1, IL-18, and IL-33 gene polymorphisms with late-onset Alzheimer's disease in a Hunan Han Chinese population 期刊论文
Brain Research, 2015, 卷号: 1596, 期号: Volume 1596, 页码: 136-145
作者:  Tian, M;  Deng, Y Y;  Hou, D R;  Li, W;  Feng, X L
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/03
AD  Alzheimer׳s disease  LOAD  late-onset Alzheimer׳s disease  EOAD  early-onset Alzheimer׳s disease    amyloid-beta  APOE  apolipoprotein E  APP  amy1iod precursor protein  CAA  cerebral amyloid angiopathy  CNS  central nervous system  IL  interleukin  ACT  alpha1-antichymotrypsin  TNF  tumor necrosis factor  BMI  body mass index  TC  total cholesterol  TG  triglycerides  HDL-c  high-density lipoprotein cholesterol  LDL-c  low-density lipoprotein cholesterol  OR  odds ratio  CI  confidence interval  MMSE  Mini-Mental State Examination  ADL  activities of daily living scale  CDT  clock drawing task  HAMD  hamilton depression scale  SNP  single nucleotide polymorphism  PCR  polymerase chain reaction  MALDI-TOF-MS  Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry  Alzheimer׳s disease  Inflammatory cytokines  IL-1 family  Single nucleotide polymorphism  
Silencing miR‐146a influences B cells and ameliorates experimental autoimmune myasthenia gravis 期刊论文
Immunology, 2015, 卷号: 144, 期号: 1, 页码: 56-67
作者:  Zhang, JunMei;  Jia, Ge;  Liu, Qun;  Hu, Jue;  Yan, Mei
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/03
Downregulation of microRNA-146a inhibits ovarian granulosa cell apoptosis by simultaneously targeting interleukin-1 receptor-associated kinase and tumor necrosis factor receptor-associated factor 6 期刊论文
MOLECULAR MEDICINE REPORTS, 2015, 卷号: 12, 期号: 4, 页码: 5155-5162
作者:  Chen, Xi;  Xie, Mingxuan;  Liu, Da;  Shi, Ke*
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/03


©版权所有 ©2017 CSpace - Powered by CSpace