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CORC

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Design, Synthesis, and Evaluation of Ribose-Modified Anilinopyrimidine Derivatives as EGFR Tyrosine Kinase Inhibitors 期刊论文
FRONTIERS IN CHEMISTRY, 2017, 卷号: 5
作者:  Hu, Xiuqin;  Wang, Disha;  Tong, Yi;  Tong, Linjiang;  Wang, Xia
收藏  |  浏览/下载：62/0  |  提交时间：2019/01/08
Structure-based design and synthesis of 2,4-diaminopyrimidines as EGFR L858R/T790M selective inhibitors for NSCLC 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 510-527
作者:  Chen, Lingfeng;  Fu, Weitao;  Feng, Chen;  Qu, Rong;  Tong, Linjiang
收藏  |  浏览/下载：57/0  |  提交时间：2019/01/08
Prognostic and predictive value of serum carcinoembryonic antigen levels in advanced non-small cell lung cancer patients with epidermal growth factor receptor sensitive mutations and receiving tyrosine kinase inhibitors 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 41
作者:  Zhao, Xin Min;  Zhao, Jing;  Xing, Kai Lin;  Sun, Si;  Luo, Zhi Guo
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/05
Prognostic role of N-Acetylgalactosaminyltransferase 10 in metastatic renal cell carcinoma 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 9
作者:  Liu, Li;  Xiong, Ying;  Xi, Wei;  Wang, Jiajun;  Qu, Yang
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/05
Mimicking the BIM BH3 domain overcomes resistance to EGFR tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 65
作者:  Xia, Jinjing;  Bai, Hao;  Yan, Bo;  Li, Rong;  Shao, Minhua
收藏  |  浏览/下载：5/0  |  提交时间：2019/12/05
Dynamics of EGFR mutations in plasma recapitulates the clinical response to EGFR-TKIs in NSCLC patients 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 38
作者:  Xiong, Liwen;  Cui, Shaohua;  Ding, Jingyan;  Sun, Yun;  Zhang, Longfu
收藏  |  浏览/下载：8/0  |  提交时间：2019/12/05
Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance 期刊论文
European Journal of Medicinal Chemistry, 2017, 卷号: 135, 页码: 34-48
作者:  Zha, Gao-Feng;  Qin, Hua-Li*;  Youssif, Bahaa G. M.;  Amjad, Muhammad Wahab;  Raja, Maria Abdul Ghafoor
收藏  |  浏览/下载：14/0  |  提交时间：2019/12/04
Epidermal growth factor receptor (EGFR)  BRAF  Focal adhesion kinase (FAK)  Tubulin polymerization  Cancer cell lines  MDR  multidrug resistance  EGFR  epidermal growth factor receptor  EMEA  European Medicines Evaluation Agency  FDA  US Food and Drug Administration  NSCLC  non-small cell lung  FAK  focal adhesion kinase  RTK  receptor tyrosine kinases  MAPK  mitogen-activated protein kinase  ABC  ATP-binding cassette  NF-kB  NF-kappaB  FERM  Four-point-one, ezrin, radixin, moesin  TMP  Ligustrazine or tetramethylpyrazine  Adr  Adriamycin  DRS  death receptors  TFN  tumor necrosis factor  PI  propidium iodide  TKIs  tyrosine kinase inhibitors  FAR  fluorescence activity ratio  HRMS  high resolution mass spectra  TLC  thin layer chromatography  UV  ultraviolet  DMEM  Dulbecco's modified Eagle's medium  DMSO  dimethyl sulfoxide  IBX  2-iodoxybenzoic acid  
Synthesis and evaluation of osimertinib derivatives as potent EGFR inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017
Gao, Hongying; Yang, Zimo; Yang, Xinglin; Rao, Yu
收藏  |  浏览/下载：7/0  |  提交时间：2017/12/03
Discovery and evaluation of triple inhibitors of VEGFR-2, TIE-2 and EphB4 as anti-angiogenic and anti-cancer agents 期刊论文
ONCOTARGET, 2017, 卷号: 8, 页码: 104745-104760
作者:  Zhang, Lin;  Shan, Yuanyuan;  Ji, Xingyue;  Zhu, Mengyuan;  Li, Chuansheng
收藏  |  浏览/下载：6/0  |  提交时间：2019/11/26
EGFR T790M ctDNA testing platforms and their role as companion diagnostics: Correlation with clinical outcomes to EGFR-TKIs 期刊论文
Cancer Letters, 2017, 卷号: Vol.403, 页码: 186-194
作者:  Liang, Z.;  Cheng, Y.;  Chen, Y.;  Hu, Y.;  Liu, W.-P.
收藏  |  浏览/下载：4/0  |  提交时间：2019/02/25

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