QQ客服 官方微博 反馈留言

浏览/检索结果: 共9条，第1-9条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis 期刊论文 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6 作者:  Yang, Xiangbo;  Lu, Huimin;  Xie, Hang;  Zhang, Binbin;  Nie, Tianqing 收藏  |  浏览/下载：25/0  |  提交时间：2022/01/18 Binding studies  Drug discovery  Necroptosis  RIPK1 inhibitors  Sepsis   Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease 期刊论文 NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 12 作者:  Su, Haixia;  Yao, Sheng;  Zhao, Wenfeng;  Zhang, Yumin;  Liu, Jia 收藏  |  浏览/下载：30/0  |  提交时间：2021/08/17 What coronavirus 3C-like protease tells us: From structure, substrate selectivity, to inhibitor design 期刊论文 MEDICINAL RESEARCH REVIEWS, 2021, 页码: 34 作者:  Xiong, Muya;  Su, Haixia;  Zhao, Wenfeng;  Xie, Hang;  Shao, Qiang 收藏  |  浏览/下载：42/0  |  提交时间：2021/05/24 3C-like protease  binding modes  coronavirus  inhibitors  structure and function   Synthesis and biological activity of C-7, C-9 and C-10 modified taxane analogues from 1-deoxybaccatin VI 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 21, 页码: 8 作者:  Xie, Chenghu;  Cui, Yongmei;  Li, Lanlan;  Zhang, Minmin;  Liu, Hongchun 收藏  |  浏览/下载：74/0  |  提交时间：2020/12/21 Paclitaxel  Taxane analogues  1-Deoxybaccatin VI  Synthesis  In vitro anticancer activity   Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir 期刊论文 SCIENCE, 2020, 卷号: 368, 期号: 6498, 页码: 1499-+ 作者:  Yin, Wanchao;  Mao, Chunyou;  Luan, Xiaodong;  Shen, Dan-Dan;  Shen, Qingya 收藏  |  浏览/下载：58/0  |  提交时间：2020/12/24 Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease 期刊论文 SCIENCE, 2020, 卷号: 368, 期号: 6497, 页码: 1331-+ 作者:  Dai, Wenhao;  Zhang, Bing;  Jiang, Xia-Ming;  Su, Haixia;  Li, Jian 收藏  |  浏览/下载：30/0  |  提交时间：2020/12/24 Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 8, 页码: 4090-4106 作者:  Su, Haixia;  Zou, Yi;  Chen, Guofeng;  Dou, Huixia;  Xie, Hang 收藏  |  浏览/下载：32/0  |  提交时间：2020/07/01 Facile synthesis of 2-C-methyl-D-arabino-gamma-1,4-lactones and mechanism study 期刊论文 TETRAHEDRON LETTERS, 2018, 卷号: 59, 期号: 15, 页码: 1473-1475 作者:  Lv, Bingqing;  Guo, Shuang;  Zhu, Fuqiang;  Hu, Tianwen;  Guo, Qi 收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 Nucleoside  2-C-Methyl-D-arabino-gamma-lactone  Mechanism  SN2 reaction  O-18-labelled DMSO   Solvent-free synthesis of delta-carbolines/carbazoles from 3-nitro-2-phenylpyridines/2-nitrobiphenyl derivatives using DPPE as a reducing agent 期刊论文 TETRAHEDRON, 2011, 卷号: 67, 期号: 32, 页码: 5725-5731 作者:  Peng, Haixia;  Chen, Xuxing;  Chen, Yanhong;  He, Qian;  Xie, Yuyuan 收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08 Solvent-free  delta-Carbolines  Carbazoles  Cadogen cyclization  DPPE