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Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Zhou, Yu-bo;  Zhang, Yang-ming;  Huang, Hong-hui;  Shen, Li-jing;  Han, Xiao-feng
收藏  |  浏览/下载:96/0  |  提交时间:2021/11/04
Further new cembranoids from the South China Sea soft coral Sarcophyton trocheliophorum 期刊论文
FITOTERAPIA, 2021, 卷号: 151, 页码: 5
作者:  Chen, Zi-Hui;  Gao, Tian-Run;  Yang, Min;  Yao, Li-Gong;  Guo, Yue-Wei
收藏  |  浏览/下载:21/0  |  提交时间:2021/08/17
Effects of structural changes on the enhanced hydrogen evolution reaction for Pd NPs @ 2H-MoS2 studied by in-Situ Raman spectroscopy 期刊论文
CHEMICAL PHYSICS LETTERS, 2021, 卷号: 764, 页码: 6
作者:  Li, Zhaoxia;  Peng, Chunlei;  Yin, Handi;  Ruan, Yinjie;  Sun, Yue
收藏  |  浏览/下载:61/0  |  提交时间:2021/05/24
A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumatoid arthritis 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:  Liu, Yu-ting;  Ding, Hui-hua;  Lin, Ze-min;  Wang, Que;  Chen, Li
收藏  |  浏览/下载:24/0  |  提交时间:2021/05/24
Identification of 2-substituted pyrrolo[1,2-b]pyridazine derivatives as new PARP-1 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 31, 页码: 4
作者:  Xiang, Hao-Yue;  Chen, Jian-Yang;  Huan, Xia-Juan;  Chen, Yi;  Gao, Zhao-bing
收藏  |  浏览/下载:15/0  |  提交时间:2021/05/24
Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 10
作者:  Xiang, Hao-Yue;  Wang, Xiang;  Chen, Yan-Hong;  Zhang, Xi;  Tan, Cun
收藏  |  浏览/下载:36/0  |  提交时间:2021/05/24
A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP-Protein Interactions in Kidney Cancer Cells 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2020, 页码: 274-280
作者:  Wang, Zhen;  Zhang, Hao;  Chen, Baoen;  Ouyang, Sisheng;  Zheng, Tong
收藏  |  浏览/下载:124/0  |  提交时间:2021/05/24
Enantioselective [4+2] Cycloaddition Reaction of Vinylquinolines with Dienals Enabled by Synergistic Organocatalysis 期刊论文
ORGANIC LETTERS, 2020, 卷号: 22, 期号: 15, 页码: 6061-6066
作者:  Chen, Jing;  Fu, Yiwei;  Yu, Yang;  Wang, Jian-Rong;  Guo, Yue-Wei
收藏  |  浏览/下载:22/0  |  提交时间:2020/12/24
Design, synthesis and antiproliferative activity evaluation of a series of pyrrolo [2,1-f] [1,2,4] triazine derivatives 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 12, 页码: 4
作者:  Xiang, Hao-Yue;  Chen, Yan-Hong;  Wang, Yi;  Zhang, Xi;  Ding, Jian
收藏  |  浏览/下载:42/0  |  提交时间:2020/07/01
Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion 期刊论文
ADVANCED SCIENCE, 2020, 页码: 13
作者:  Sun, Zhongya;  Zhang, Hao;  Zhang, Yuanyuan;  Liao, Liping;  Zhou, Wen
收藏  |  浏览/下载:107/0  |  提交时间:2020/07/01


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