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科研机构
上海药物研究所 [123]
内容类型
期刊论文 [112]
专利 [6]
会议论文 [5]
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2021 [12]
2020 [6]
2019 [6]
2018 [12]
2017 [3]
2016 [9]
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Pharmacol... [12]
Immunology [3]
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Synthesis and pharmacological evaluation of choroquine derivatives bearing long aminated side chains as antivirus and anti-inflammatory agents
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 8
作者:
Song, Zilan
;
Liu, Yuting
;
Xie, Chenghu
;
Tong, Xiankun
;
Wang, Xue
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2021/11/04
Choroquine
Aminochloroquine
Antivirus
Anti-inflammatory
Cytokines
Spiro ent-Clerodane Dimers: Discovery and Green Approaches for a Scalable Biomimetic Synthesis
期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 15, 页码: 5647-5651
作者:
Li, Xing-Ren
;
Yan, Bing-Chao
;
Hu, Kun
;
He, Shijun
;
Sun, Han-Dong
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/11/04
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target
期刊论文
CELL RESEARCH, 2021, 页码: 14
作者:
Xia, Bingqing
;
Shen, Xurui
;
He, Yang
;
Pan, Xiaoyan
;
Liu, Feng-Liang
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2021/08/17
(-)-Isoscopariusin A, a Naturally Occurring Immunosuppressive Meroditerpenoid: Structure Elucidation and Scalable Chemical Synthesis
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 10
作者:
Yan, Bing-Chao
;
Zhou, Min
;
Li, Jian
;
Li, Xiao-Nian
;
He, Shi-Jun
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2021/05/24
bioactivity
cyclobutane
natural products
scalable synthesis
structure elucidation
Rh-Catalyzed C-H alkylation enabling modular synthesis of CF3-substituted benzannulated macrocyclic inhibitors of B cell responses dagger
期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 页码: 6
作者:
Sun, Tao
;
He, Shijun
;
Xu, Zhongliang
;
Zuo, Jianping
;
Yu, Yang
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/05/24
Minor immunosuppressive spiroorthoester group-containing pregnane glycosides from the root barks of Periploca sepium
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 10
作者:
Shao, Xing-Cheng
;
Chen, Zhen-Hua
;
Liu, Shuang-Shuang
;
Wu, Fei
;
Mu, Hong-Yan
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
Periploca sepium
Pregnane glycosides
Spiroorthoester group
Immunosuppression
Marine furanocembranoids-inspired macrocycles enabled by Pd-catalyzed unactivated C(sp(3))-H olefination mediated by donor/donor carbenes
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 11
作者:
Hao, Jiping
;
Guo, Xueying
;
He, Shijun
;
Xu, Zhongliang
;
Chen, Lu
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/05/24
NOD-like receptors in autoimmune diseases
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 15
作者:
Chen, Li
;
Cao, Shi-qi
;
Lin, Ze-min
;
He, Shi-jun
;
Zuo, Jian-ping
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/05/24
pattern recognition receptors
NOD-like receptors
autoimmune diseases
inflammasomes
inhibitors
botanicals
DZ2002 alleviates psoriasis-like skin lesions via differentially regulating methylation of GATA3 and LCN2 promoters
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 卷号: 91, 页码: 12
作者:
Chen, Li
;
Lin, Zemin
;
Liu, Yuting
;
Cao, Shiqi
;
Huang, Yueteng
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2021/05/24
DZ2002
Psoriasis
DNA methylation
Keratinocyte
Inflammatory infiltration
Anti-nociceptive, anti-inflammatory and anti-arthritic activities of pregnane glycosides from the root bark of Periploca sepium Bunge
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 265, 页码: 12
作者:
Lin, Ze-min
;
Liu, Yu-ting
;
Huang, Yue-teng
;
Yang, Xiao-qian
;
Zhu, Feng-hua
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/05/24
Periploca sepium Bunge
Pregnane glycosides
Anti-nociceptive activity
Anti-inflammatory activity
Anti-arthritic activity
Inflammatory arthritis
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