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科研机构
上海药物研究所 [45]
内容类型
期刊论文 [45]
发表日期
2021 [45]
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发表日期:2021
专题:上海药物研究所
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STING inhibitor ameliorates LPS-induced ALI by preventing vascular endothelial cells-mediated immune cells chemotaxis and adhesion
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Wu, Bing
;
Xu, Meng-meng
;
Fan, Chen
;
Feng, Chun-lan
;
Lu, Qiu-kai
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2022/01/18
acute lung injury
STING
vascular endothelial cells
inflammatory cytokines
chemokines
chemotaxis
Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9
作者:
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2022/01/04
phosphoinositide 3-kinase (PI3K)
activation
inhibition
activity-dependent conformational changes
Transfersomes improved delivery of ascorbic palmitate into the viable epidermis for enhanced treatment of melasma
期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2021, 卷号: 608, 页码: 10
作者:
Li, Junjun
;
Duan, Nianxiu
;
Song, Sha
;
Nie, Di
;
Yu, Miaorong
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2021/11/04
Transfersome
Drug delivery
Ascorbic palmitate
Viable epidermis
Melasma treatment
Constitutive signal bias mediated by the human GHRHR splice variant 1
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 40, 页码: 10
作者:
Cong, Zhaotong
;
Zhou, Fulai
;
Zhang, Chao
;
Zou, Xinyu
;
Zhang, Huibing
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/12/01
class B1 GPCR
receptor bias
cancer
cell proliferation
Sinunanolobatone A, an Anti-inflammatory Diterpenoid with Bicyclo[13.1.0]pentadecane Carbon Scaffold, and Related Casbanes from the Sanya Soft Coral Sinularia nanolobata
期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 19, 页码: 7575-7579
作者:
Zeng, Zi-Rong
;
Li, Wang-Sheng
;
Nay, Bastien
;
Hu, Pei
;
Zhang, Hai-Yan
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  |  
浏览/下载:21/0
  |  
提交时间:2021/12/01
New formamidobisabolene-type sesquiterpenoids from a Hainan Sponge Halichondria sp.
期刊论文
TETRAHEDRON, 2021, 卷号: 96, 页码: 7
作者:
Chen, Bao
;
Li, Wang-Sheng
;
Gu, Yu-Cheng
;
Zhang, Hai-Yan
;
Luo, Hui
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/11/04
Sponge
Halichondria sp
Anti-inflammatory activity
Sesquiterpenes
Novel selective kappa agonists SLL-039 and SLL-1206 produce potent antinociception with fewer sedation and aversion
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Wei, Yuan-yuan
;
Ma, Yan
;
Yao, Song-yu
;
Kong, Ling-hui
;
Liu, Xiao
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  |  
浏览/下载:42/0
  |  
提交时间:2021/11/04
kappa-opioid receptor agonist
4,5-expoxymorphinan
antinociception
conditioned place aversion
sedation
U50,488H
morphine
Nor-BNI
beta-FNA
Gut Microbiota in Adipose Tissue Dysfunction Induced Cardiovascular Disease: Role as a Metabolic Organ
期刊论文
FRONTIERS IN ENDOCRINOLOGY, 2021, 卷号: 12, 页码: 14
作者:
Yang, Xinyu
;
Zhang, Xianfeng
;
Yang, Wei
;
Yu, Hang
;
He, Qianyan
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/11/04
gut microbiota
adipose tissue dysfunction
molecular endocrinology
cardiovascular disease(s)
gut dysbiosis
Imatinib inhibits the malignancy of hepatocellular carcinoma by suppressing autophagy
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 906, 页码: 8
作者:
Xiao, Meng-Chao
;
Qian, Hui
;
Huang, Chen-Kai
;
Zheng, Bai-Nan
;
Yan, Fang-Zhi
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/11/04
Imatinib
Autophagy
Hepatocarcinoma
Sorafenib
Synergetic effect
Structural mechanism of calcium-mediated hormone recognition and G beta interaction by the human melanocortin-1 receptor
期刊论文
CELL RESEARCH, 2021, 页码: 11
作者:
Ma, Shanshan
;
Chen, Yan
;
Dai, Antao
;
Yin, Wanchao
;
Guo, Jia
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/11/04
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