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CORC

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Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14822-14847
作者:  Wei, Dan;  Wang, Hanlin;  Zeng, Qinghe;  Wang, Wenjing;  Hao, Bingbing
收藏  |  浏览/下载：30/0  |  提交时间：2021/12/16
Global identification of phospho-dependent SCF substrates reveals a FBXO22 phosphodegron and an ERK-FBXO22-BAG3 axis in tumorigenesis 期刊论文
CELL DEATH AND DIFFERENTIATION, 2021, 页码: 13
作者:  Liu, Ping;  Cong, Xiaoji;  Liao, Shengjie;  Jia, Xinglong;  Wang, Xiaomin
收藏  |  浏览/下载：78/0  |  提交时间：2021/08/17
miR-34a-5p regulates PINK1-mediated mitophagy via multiple modes 期刊论文
LIFE SCIENCES, 2021, 卷号: 276, 页码: 13
作者:  Tai, Yusi;  Pu, Mei;  Yuan, Luyang;  Guo, Huijie;  Qiao, Junwen
收藏  |  浏览/下载：49/0  |  提交时间：2021/08/17
Ube2b-dependent degradation of DNMT3a relieves a transcriptional brake on opiate-induced synaptic and behavioral plasticity 期刊论文
MOLECULAR PSYCHIATRY, 2021, 卷号: 26, 期号: 4, 页码: 1162-1177
作者:  Chen, Zhong-Guo;  Wang, Yu-Jun;  Chen, Ruo-Song;  Geng, Fan;  Gan, Chen-Ling
收藏  |  浏览/下载：17/0  |  提交时间：2021/05/24
SL010110, a lead compound, inhibits gluconeogenesis via SIRT2-p300-mediated PEPCK1 degradation and improves glucose homeostasis in diabetic mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:  Ren, Yu-ran;  Ye, Yang-liang;  Feng, Ying;  Xu, Ti-fei;  Shen, Yu
收藏  |  浏览/下载：22/0  |  提交时间：2021/05/24
A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP-Protein Interactions in Kidney Cancer Cells 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2020, 页码: 274-280
作者:  Wang, Zhen;  Zhang, Hao;  Chen, Baoen;  Ouyang, Sisheng;  Zheng, Tong
收藏  |  浏览/下载：124/0  |  提交时间：2021/05/24
Deubiquitinase USP29 promotes gastric cancer cell migration by cooperating with phosphatase SCP1 to stabilize Snail protein 期刊论文
ONCOGENE, 2020, 页码: 14
作者:  Qian, Wenli;  Li, Qi;  Wu, Xinglong;  Li, Wenguo;  Li, Qiwei
收藏  |  浏览/下载：34/0  |  提交时间：2020/12/21
Discovery of novel USP8 inhibitors via Ubiquitin-Rho-110 fluorometric assay based high throughput screening 期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 9
作者:  Han, Jie;  Tian, Yucheng;  Yu, Liang;  Zhang, Qilin;  Xu, Xi
收藏  |  浏览/下载：61/0  |  提交时间：2020/12/24
Structure-Activity Relationship of SPOP Inhibitors against Kidney Cancer 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 9, 页码: 4849-4866
作者:  Dong, Ze;  Wang, Zhen;  Guo, Zhong-Qiang;  Gong, Shouzhe;  Zhang, Tao
收藏  |  浏览/下载：42/0  |  提交时间：2020/07/01
The novel cereblon modulator CC-885 inhibits mitophagy via selective degradation of BNIP3L 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:  Hao, Bing-bing;  Li, Xiao-jing;  Jia, Xing-long;  Wang, Yu-xing;  Zhai, Lin-hui
收藏  |  浏览/下载：45/0  |  提交时间：2020/07/01

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