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科研机构
上海药物研究所 [18]
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期刊论文 [18]
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2021 [1]
2019 [1]
2018 [2]
2016 [3]
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A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumatoid arthritis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Liu, Yu-ting
;
Ding, Hui-hua
;
Lin, Ze-min
;
Wang, Que
;
Chen, Li
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
rheumatoid arthritis
BTK inhibitors
B cells
macrophages
RANKL
osteoclastogenesis
Inhibition of HSP90 beta Improves Lipid Disorders by Promoting Mature SREBPs Degradation via the Ubiquitin-proteasome System
期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 20, 页码: 5769-5783
作者:
Zheng, Zu-Guo
;
Zhang, Xin
;
Liu, Xiao-Xiao
;
Jin, Xiu-Xiu
;
Dai, Lunzhi
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
HSP90 beta
lipid metabolism
corylin
SREBPs
proteasomal degradation
Effect of Medium-chain Fatty Acid-sensing Receptor GPR84 on Glucose and Lipid Metabolism in Mice
期刊论文
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2018, 卷号: 45, 期号: 8, 页码: 853-864
作者:
Fang You-Chen
;
Zheng Yang
;
Zheng Qing
;
Li Jing
;
Xie Xin
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
GPR84
medium-chain fatty acid-sensing receptor
obesity
lipid metabolism
hypercholesterolemia
Linderane Suppresses Hepatic Gluconeogenesis by Inhibiting the cAMP/PKA/CREB Pathway Through Indirect Activation of PDE 3 via ERK/STAT3
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Xie, Wei
;
Ye, Yangliang
;
Feng, Ying
;
Xu, Tifei
;
Huang, Suling
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/01/08
cAMP
gluconeogenesis
linderane
phosphodiesterase
type 2 diabetes
OL3, a novel low-absorbed TGR5 agonist with reduced side effects, lowered blood glucose via dual actions on TGR5 activation and DPP-4 inhibition
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1359-1369
作者:
Ma, Shan-yao
;
Ning, Meng-meng
;
Zou, Qing-an
;
Feng, Ying
;
Ye, Yang-liang
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
OL3
MN6
linagliptin
TGR5 agonist
DPP4 inhibitor
GLP-1
low-absorbed
gallbladder filling
type 2 diabetes mellitus
The sphingosine-1-phosphate analogue, FTY-720, promotes the proliferation of embryonic neural stem cells, enhances hippocampal neurogenesis and learning and memory abilities in adult mice
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2016, 卷号: 173, 期号: 18, 页码: 2793-2807
作者:
Sun, Yili
;
Hong, Feng
;
Zhang, Lei
;
Feng, Linyin
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Discovery of CNS Penetrant CXCR2 Antagonists for the Potential Treatment of CNS Demyelinating Disorders
期刊论文
ACS medicinal chemistry letters, 2016, 卷号: 7, 期号: 4, 页码: 397-402
作者:
Xu, Heng
;
Lu, Hongfu
;
Xu, Zhongmiao
;
Luan, Linbo
;
Li, Chengyong
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
Cordyceps sinensis protects against liver and heart injuries in a rat model of chronic kidney disease: a metabolomic analysis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 5, 页码: 697-706
作者:
Liu, Xia
;
Zhong, Fang
;
Tang, Xu-long
;
Lian, Fu-lin
;
Zhou, Qiao
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Cordyceps sinensis
chronic kidney disease
liver injury
heart injury
metabolomics
nuclear magnetic resonance
traditional Chinese medicine
Metabolomic Analysis of Anti-Hypoxia and Anti-anxiety Effects of Fu Fang Jin Jing Oral Liquid
期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 10
作者:
Liu, Xia
;
Zhu, Wei
;
Guan, Shuhong
;
Feng, Ruihong
;
Zhang, Hui
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Marine natural product des-O-methyllasiodiplodin effectively lowers the blood glucose level in db/db mice via ameliorating inflammation
期刊论文
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 10, 页码: 1325-1336
作者:
Zhou, Rong
;
Lin, Zhong-hui
;
Jiang, Cheng-shi
;
Gong, Jing-xu
;
Chen, Li-li
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
des-O-methyllasiodiplodin
diabetes
db/db mice
pro-inflammatory cytokine
ROS
mineralocorticoid receptor
aldosterone
blood glucose
glycosylated hemoglobin (HbA1c)
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