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科研机构
上海药物研究所 [21]
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期刊论文 [19]
项目 [2]
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2021 [1]
2020 [1]
2018 [1]
2017 [1]
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Transcriptome Regulation by Oncogenic ALK Pathway in Mammalian Cortical Development Revealed by Single-Cell RNA Sequencing
期刊论文
CEREBRAL CORTEX, 2021, 卷号: 31, 期号: 8, 页码: 3911-3924
作者:
Mao, Rui
;
Zhang, Xiaoyun
;
Kong, Youyong
;
Wu, Shanshan
;
Huo, Hai-qin
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2021/08/17
anaplastic lymphoma kinase
cerebral organoid
neurodevelopment
neural progenitor cell
single-cell RNA sequencing
Long non-coding RNAs in hepatocellular carcinoma: Ordering of the complicated lncRNA regulatory network and novel strategies for HCC clinical diagnosis and treatment
期刊论文
PHARMACOLOGICAL RESEARCH, 2020, 卷号: 158, 页码: 11
作者:
Li, Changyao
;
Yang, Junfa
;
Liu, Chongjing
;
Wang, Xiao
;
Zhang, Lei
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/12/24
Hepatocellular carcinoma
Long non-coding RNA
Exosomes
Death-domain dimerization-mediated activation of RIPK1 controls necroptosis and RIPK1-dependent apoptosis
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: 115, 期号: 9, 页码: E2001-E2009
作者:
Meng, Huyan
;
Liu, Zhen
;
Li, Xingyan
;
Wang, Huibing
;
Jin, Taijie
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
RIPK1
death domain
dimerization
necroptosis
RIPK1-dependent apoptosis
Ancient hybridization and strong adaptation to viruses across African vervet monkey populations
期刊论文
NATURE GENETICS, 2017, 卷号: 49, 期号: 12, 页码: 1705-+
作者:
Svardal, Hannes
;
Jasinska, Anna J.
;
Apetrei, Cristian
;
Coppola, Giovanni
;
Huang, Yu
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
A novel GSK-3 beta inhibitor YQ138 prevents neuronal injury induced by glutamate and brain ischemia through activation of the Nrf2 signaling pathway
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 6, 页码: 741-752
作者:
Pang, Tao
;
Wang, Yun-jie
;
Gao, Yuan-xue
;
Xu, Yuan
;
Li, Qiu
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
GSK-3 beta inhibitor
YQ138
cerebellar granule cells
glutamate excitotoxicity
OGD
middle cerebral artery occlusion
brain ischemia
neuroprotection
Nrf2
KCNQ potassium channels in sensory system and neural circuits
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 1, 页码: 25-33
作者:
Wang, Jing-jing
;
Li, Yang
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
KCNQ channels
M channels
neural circuits
channelopathy
epilepsy
neuropathic pain
deafness
mental illness
Telmisartan prevention of LPS-induced microglia activation involves M2 microglia polarization via CaMKK beta-dependent AMPK activation
期刊论文
BRAIN BEHAVIOR AND IMMUNITY, 2015, 卷号: 50, 页码: 298-313
作者:
Xu, Yuan
;
Xu, Yazhou
;
Wang, Yurong
;
Wang, Yunjie
;
He, Ling
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
Telmisartan
Microglia polarization
AMP-activated protein kinase
Neuroinflammation
Ion channels gated by acetylcholine and serotonin: structures, biology, and drug discovery
期刊论文
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 8, 页码: 895-907
作者:
Wu, Zhong-shan
;
Cheng, Hao
;
Jiang, Yi
;
Melcher, Karsten
;
Xu, H. Eric
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
nAChR
5-HT3R
structure biology
subunit composition
channel activation
channel gating
ion selectivity
neurological disorders
Targeting the Small- and Intermediate-Conductance Ca2+-Activated Potassium Channels: The Drug-Binding Pocket at the Channel/Calmodulin Interface
期刊论文
NEUROSIGNALS, 2014, 卷号: 22, 期号: 2, 页码: 65-78
作者:
Cui, Meng
;
Qin, Guangrong
;
Yu, Kunqian
;
Bowers, M. Scott
;
Zhang, Miao
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Small- and intermediate-conductance Ca2+-activated potassium channels
Small-molecule positive modulators
Structure-based drug discovery
Ataxia
Alcohol use disorders
Parkinson's disease
Targeting Epigenetics in Nervous System Disease
期刊论文
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS, 2013, 卷号: 12, 期号: 1, 页码: 126-141
作者:
Zhang, Ruihan
;
Lu, Junyan
;
Kong, Xiangqian
;
Jin, Lu
;
Luo, Cheng
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
DNA methyltransferase
epigenetics
glioma
histone deacetylase
histone methyltransferase
nervous system disease
neurodevelopmental disease
neurodegenerative disease
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