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科研机构
上海药物研究所 [37]
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期刊论文 [37]
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2021 [1]
2020 [3]
2019 [2]
2018 [2]
2017 [4]
2016 [3]
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Chemistry [1]
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Activating Adenosine Monophosphate-Activated Protein Kinase Mediates Fibroblast Growth Factor 1 Protection From Nonalcoholic Fatty Liver Disease in Mice
期刊论文
HEPATOLOGY, 2021, 卷号: 73, 期号: 6, 页码: 2206-2222
作者:
Lin, Qian
;
Huang, Zhifeng
;
Cai, Genxiang
;
Fan, Xia
;
Yan, Xiaoqing
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2021/08/17
Pulmonary Targeting Crosslinked Cyclodextrin Metal-Organic Frameworks for Lung Cancer Therapy
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 13
作者:
He, Yaping
;
Xiong, Ting
;
He, Siyu
;
Sun, Hongyu
;
Huang, Chenxi
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2020/12/21
cancer therapy
cyclodextrin frameworks
low-molecular-weight heparin
lung-targeting carriers
RGD peptide
Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856
作者:
Liu, Wen
;
Yin, Ye
;
Wang, Meijing
;
Fan, Ting
;
Zhu, Yuyu
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  |  
浏览/下载:239/0
  |  
提交时间:2020/12/24
Src homology 2 domain containing tyrosine phosphatase-2 (SHP2)
hepatic steatosis
insulin resistance
caspase-1
interleukin 18 (IL-18)
fatty liver
metabolic disorder
inflammation
cytokine signaling
caspase 1 (CASP1)
tyrosine-protein phosphatase (tyrosine phosphatase)
macrophage
Chemical structure elucidation of an inulin-type fructan isolated from Lobelia chinensis lour with anti-obesity activity on diet-induced mice
期刊论文
CARBOHYDRATE POLYMERS, 2020, 卷号: 240, 页码: 8
作者:
Zhang, Xue
;
Hu, Pei
;
Zhang, Xiaorui
;
Li, Xiaojun
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  |  
浏览/下载:51/0
  |  
提交时间:2020/12/24
Lobelia chinensis Lour polysaccharides
anti-obesity
chemical structure
inulin-type fructan
high fat diet-induced mice
Berberine promotes the recruitment and activation of brown adipose tissue in mice and humans
期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 18
作者:
Wu, Lingyan
;
Xia, Mingfeng
;
Duan, Yanan
;
Zhang, Lina
;
Jiang, Haowen
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
Tripterygium glycoside fraction n2: Alleviation of DSS-induced colitis by modulating immune homeostasis in mice
期刊论文
PHYTOMEDICINE, 2019, 卷号: 58, 页码: 12
作者:
Yang, Y. Q.
;
Wu, Y. F.
;
Xu, F. F.
;
Deng, J. B.
;
Wu, L. L.
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  |  
浏览/下载:10/0
  |  
提交时间:2020/07/01
Tripterygium wilfordii Hook F
Inflammatory bowel disease apoptosis
DSS
T lymphocytes
SILAC-based quantitative proteomic analysis of the livers of spontaneous obese and diabetic rhesus monkeys
期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2018, 卷号: 315, 期号: 2, 页码: E294-E306
作者:
Wang, Junlong
;
Xu, Shimeng
;
Gao, Jing
;
Zhang, Linqiang
;
Zhang, Zhiguo
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  |  
浏览/下载:108/0
  |  
提交时间:2019/01/08
liver
rhesus monkey
stable isotope labeling with amino acids in cell culture-based quantitative proteomics
spontaneous Type 2 diabetes
Structural Modification of Natural Product Tanshinone I Leading to Discovery of Novel Nitrogen-Enriched Derivatives with Enhanced Anticancer Profile and Improved Drug-like Properties
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 3, 页码: 760-776
作者:
Ding, Chunyong
;
Tian, Qianting
;
Li, Jie
;
Jiao, Mingkun
;
Song, Shanshan
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  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
Critical Role of Hepatic Cyp450 sin the Testis-Specific Toxicity of (5R)-5-Hydroxytriptolide in C57BL/6 Mice
期刊论文
FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8
作者:
Yu, Cunzhi
;
Li, Yu
;
Liu, Mingxia
;
Gao, Man
;
Li, Chenggang
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/01/08
(5R)-5-hydroxytriptolide
functional knockout
cytochrome P450
testes
gamma-H2AX
RNA polymerase II
androgen receptor
Plantago asiatica L. Seed Extract Improves Lipid Accumulation and Hyperglycemia in High-Fat Diet-Induced Obese Mice
期刊论文
International journal of molecular sciences, 2017, 卷号: 18, 期号: 7
作者:
Yang, Qiming
;
Qi, Meng
;
Tong, Renchao
;
Wang, Dandan
;
Ding, Lili
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
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