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科研机构
上海药物研究所 [67]
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期刊论文 [67]
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2021 [6]
2020 [3]
2019 [4]
2018 [8]
2017 [4]
2016 [6]
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Genetically-engineered "all-in-one" vaccine platform for cancer immunotherapy
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 11, 页码: 3622-3635
作者:
Wu, Aihua
;
Chen, Yingzhi
;
Wang, Hairui
;
Chang, Ya
;
Zhang, Meng
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/01/18
Trichosanthin
Legumain
TRP2
Transcutaneous immunization
Adjuvant
Cancer vaccine
Protein engineering
Synthesis and bioactivity studies of covalent inhibitors derived from (-)-Chaetominine
期刊论文
JOURNAL OF MOLECULAR STRUCTURE, 2021, 卷号: 1241, 页码: 14
作者:
Zhou, Xian
;
Feng, Xuexin
;
Wang, Dachi
;
Chen, Deheng
;
Wu, Gaoxing
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2021/08/17
Chaetominine
Cellular growth inhibition
Cancer cell line
Covalent warhead
Recombinant cancer nanovaccine for targeting tumor-associated macrophage and remodeling tumor microenvironment
期刊论文
NANO TODAY, 2021, 卷号: 40, 页码: 14
作者:
Tang, Yisi
;
Fan, Wufa
;
Chen, Guihua
;
Zhang, Meng
;
Tang, Xueping
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2021/12/01
Cancer therapeutic vaccine
Legumain
Tumor-associated macrophage
Trichosanthin
Liposome
Adjuvant
BCL9 regulates CD226 and CD96 checkpoints in CD8(+) T cells to improve PD-1 response in cancer
期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 14
作者:
Feng, Mei
;
Wu, Zhongen
;
Zhou, Yan
;
Wei, Zhuang
;
Tian, Enming
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/11/04
Discovery of novel ceramide analogs with favorable pharmacokinetic properties and combination with AKT inhibitor against colon cancer
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215, 页码: 13
作者:
Gao, Feng
;
Chen, Xiaoxu
;
Lu, Junyan
;
Hu, Shulei
;
Xu, Hui
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/05/24
Ceramide analogs
AKT inhibitor
MK2206
Colon cancer
Combination therapy
Magnetism-mediated targeting hyperthermia-immunotherapy in "cold" tumor with CSF1R inhibitor
期刊论文
THERANOSTICS, 2021, 卷号: 11, 期号: 14, 页码: 6860-6872
作者:
Fang, Yuefei
;
He, Yang
;
Wu, Canhao
;
Zhang, Meng
;
Gu, Zeyun
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/08/17
magnetic hyperthermia
CSF1R inhibitor
tumor microenvironment
tumor-associated macrophage
immune memory
targeted delivery
magnetic liposomes
DCZ5248, a novel dual inhibitor of Hsp90 and autophagy, exerts antitumor activity against colon cancer
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Chen, Xiang-ling
;
Liu, Peng
;
Zhu, Wei-liang
;
Lou, Li-guang
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/07/01
DCZ5248
Hsp90
autophagy
lysosomal function
antitumor activity
colon cancer
Patchouli Alcohol: a Natural Sesquiterpene Against Both Inflammation and Intestinal Barrier Damage of Ulcerative Colitis
期刊论文
INFLAMMATION, 2020, 页码: 13
作者:
Wu, Zhuona
;
Zeng, Hairong
;
Zhang, Lili
;
Pu, Yiqiong
;
Li, Suyun
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
patchouli alcohol
ulcerative colitis
intestinal integrity
anti-inflammatory
Synthesis and in Vitro and in Vivo Biological Evaluation of Tissue-Specific Bisthiazole Histone Deacetylase (HDAC) Inhibitors
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 2, 页码: 804-815
作者:
Zhang, Shu-Wei
;
Gong, Chao-Jun
;
Su, Ming-Bo
;
Chen, Fei
;
He, Ting
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
Identifying a ten-microRNA signature as a superior prognosis biomarker in colon adenocarcinoma
期刊论文
CANCER CELL INTERNATIONAL, 2019, 卷号: 19, 期号: 1, 页码: 16
作者:
Ma, Rong
;
Zhao, Yanyun
;
He, Miao
;
Zhao, Hongliang
;
Zhang, Yifan
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2020/07/01
Colon adenocarcinoma
MicroRNAs
Biomarker
Prognosis
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