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Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK 期刊论文
CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 19, 页码: 2243-2263
作者:  Elksnis, Andris;  Schiffer, Tomas A.;  Palm, Fredrik;  Wang, Yun;  Cen, Jing
收藏  |  浏览/下载:22/0  |  提交时间:2021/12/01
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir 期刊论文
SCIENCE, 2020, 卷号: 368, 期号: 6498, 页码: 1499-+
作者:  Yin, Wanchao;  Mao, Chunyou;  Luan, Xiaodong;  Shen, Dan-Dan;  Shen, Qingya
收藏  |  浏览/下载:58/0  |  提交时间:2020/12/24
Design, synthesis and. biological evaluation of 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines as novel adenosine 5 '-monophosphate-activated protein kinase (AMPK) indirect activators for the treatment of type 2 diabetes 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 448-464
作者:  Zhou, Shengbin;  Duan, Yanan;  Wang, Jiang;  Zhang, Jin;  Sun, Haifeng
收藏  |  浏览/下载:35/0  |  提交时间:2019/01/08
Novel Small-Molecule AMP-Activated Protein Kinase Allosteric Activator with Beneficial Effects in db/db Mice 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 8
作者:  Zhang, Li-Na;  Xu, Lei;  Zhou, Hua-Yong;  Wu, Ling-Yan;  Li, Yuan-Yuan
收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08
Arctigenin preferentially induces tumor cell death under glucose deprivation by inhibiting cellular energy metabolism 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2012, 卷号: 84, 期号: 4, 页码: 468-476
作者:  Gu, Yuan;  Qi, Chunting;  Sun, Xiaoxiao;  Ma, Xiuquan;  Zhang, Haohao
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
Arctigenin, a natural compound, activates AMP-activated protein kinase via inhibition of mitochondria complex I and ameliorates metabolic disorders in ob/ob mice 期刊论文
DIABETOLOGIA, 2012, 卷号: 55, 期号: 5, 页码: 1469-1481
作者:  Huang, S. -L.;  Yu, R. -T.;  Gong, J.;  Feng, Y.;  Dai, Y. -L.
收藏  |  浏览/下载:13/0  |  提交时间:2019/01/08
Nonstructural Proteins 7 and 8 of Feline Coronavirus Form a 2:1 Heterotrimer That Exhibits Primer-Independent RNA Polymerase Activity 期刊论文
JOURNAL OF VIROLOGY, 2012, 卷号: 86, 期号: 8, 页码: 4444-4454
作者:  Xiao, Yibei;  Ma, Qingjun;  Restle, Tobias;  Shang, Weifeng;  Svergun, Dmitri I.
收藏  |  浏览/下载:11/0  |  提交时间:2019/01/08
Tetramethylpyrazine protects palmitate-induced oxidative damage and mitochondrial dysfunction in C2C12 myotubes 期刊论文
LIFE SCIENCES, 2011, 卷号: 88, 期号: 17-18, 页码: 803-809
作者:  Gao, Xin;  Zhao, Xiao-long;  Zhu, Yan-hui;  Li, Xiao-mu;  Xu, Qiong
收藏  |  浏览/下载:11/0  |  提交时间:2019/01/08
Tetrahydroberberine blocks ATP-sensitive potassium channels in dopamine neurons acutely-dissociated from rat substantia nigra pars compacta 期刊论文
NEUROPHARMACOLOGY, 2010, 卷号: 59, 期号: 7-8, 页码: 567-572
作者:  Wu, Chen;  Yang, Kechun;  Liu, Qiang;  Wakui, Matoko;  Jin, Guo-Zhang
收藏  |  浏览/下载:16/0  |  提交时间:2019/01/08
AMPK Activators as Novel Therapeutics for Type 2 Diabetes 期刊论文
CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2010, 卷号: 10, 期号: 4, 页码: 397-410
作者:  Yu, Li-Fang;  Qiu, Bei-Ying;  Nan, Fa-Jun;  Li, Jia
收藏  |  浏览/下载:9/0  |  提交时间:2019/01/08


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