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科研机构
上海药物研究所 [75]
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期刊论文 [74]
会议论文 [1]
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2021 [2]
2020 [3]
2018 [4]
2017 [2]
2016 [3]
2015 [2]
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Pharmacolo... [4]
Chemistry [2]
Neuroscien... [2]
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Psychiatry [1]
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Paeoniflorin ameliorates ischemic injury in rat brain via inhibiting cytochrome c/caspase3/HDAC4 pathway
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Liu, Yi-fei
;
Zhang, Lei
;
Wu, Qi
;
Feng, Lin-yin
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/06/11
ischemic brain injury
paeoniflorin
MCAO
HDAC4
cytochrome c
apoptosis
Paeoniflorin ameliorates ischemic injury in rat brain via inhibiting cytochrome c/caspase3/HDAC4 pathway
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Liu, Yi-fei
;
Zhang, Lei
;
Wu, Qi
;
Feng, Lin-yin
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/06/11
ischemic brain injury
paeoniflorin
MCAO
HDAC4
cytochrome c
apoptosis
Structural elucidation of a pectin from roots of Polygala tenuifolia and its neuritogenesis inducing activity in PC12 cells
期刊论文
CARBOHYDRATE POLYMERS, 2020, 卷号: 236, 页码: 9
作者:
Zeng, Hui
;
Huang, Lulin
;
Tao, Hong
;
Zhang, Yiwen
;
Ding, Kan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Polygala tenuifolia
Pectin
Neuritogenesis
Neurodegenerative disorders
An optically active isochroman-2H-chromene conjugate potently suppresses neuronal oxidative injuries associated with the PI3K/Akt and MAPK signaling pathways
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Tao, Ling-xue
;
Ji, Sha-sha
;
Szaloki, Dora
;
Kovacs, Tibor
;
Mandi, Attila
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  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
neurodegeneration
oxidative stress
apoptosis
MAPK pathway
PI3K
Akt pathway
SH-SY5Y neuroblastoma cells
Engineering Versatile Nanoparticles for Near-Infrared Light-Tunable Drug Release and Photothermal Degradation of Amyloid beta
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 12
作者:
Lai, Yi
;
Zhu, Yingying
;
Xu, Zhiai
;
Hu, Xianli
;
Saeed, Madiha
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
Alzheimer's disease
amyloid beta
conjugated polymer
light-triggered drug release
photothermal degradation
The PGC-1 alpha Activator ZLN005 Ameliorates Ischemia-Induced Neuronal Injury In Vitro and In Vivo
期刊论文
CELLULAR AND MOLECULAR NEUROBIOLOGY, 2018, 卷号: 38, 期号: 4, 页码: 929-939
作者:
Xu, Yazhou
;
Kabba, John Alimamy
;
Ruan, Wenchen
;
Wang, Yunjie
;
Zhao, Shunyi
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/01/08
Ischemic stroke
PGC-1 alpha
HO-1
Neuroprotection
Chemoenzymatically synthesized GM3 analogues as potential therapeutic agents to recover nervous functionality after injury by inducing neurite outgrowth
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 146, 页码: 613-620
作者:
Zheng, Changping
;
Qu, Huanhuan
;
Liao, Wenfeng
;
Bavaro, Teodora
;
Terreni, Marco
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  |  
浏览/下载:53/0
  |  
提交时间:2019/01/08
Ganglioside GM3
Chemoenzymatic synthesis
PC12 cells
Neurite outgrowth
Characterization of a pectin from Lonicera japonica Thunb. and its inhibition effect on A beta(42) aggregation and promotion of neuritogenesis
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 107, 页码: 112-120
作者:
Liu, Qin
;
Fang, Jianping
;
Wang, Peipei
;
Du, Zhenyun
;
Li, Yanling
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
Rhamnogalacturonan I (RG-I) pectic polysaccharide
Lonicera japonica Thunb.
A beta(42) aggregation
Neuritogenesis
Alzheimer's disease
Effect of microenvironment on beta-site amyloid precursor protein cleaving enzyme 1 expression in PC12 Cells
期刊论文
Journal of Shanghai Jiaotong University .Medical Science, 2018, 卷号: 38, 期号: 9, 页码: 1005-1012
作者:
Yang Huanqing
;
He Xiang
;
Du Xiaoguang
;
Xiao Shifu
;
Wang Tao
收藏
  |  
浏览/下载:136/0
  |  
提交时间:2019/01/08
Alzheimer's disease
microenvironment
PC12 cell
beta-site amyloid precursor protein cleaving enzyme 1 (BACE1)
amyloid-beta peptide (Abeta)
Incorporation of Dihydroartemisinin into Memantine Through a Propriate Spacer to Make Hybrid with Enhanced Effects to Protect PC12 Cells from Corticosterone-caused Impairments
期刊论文
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2017, 卷号: 33, 期号: 4, 页码: 611-622
作者:
Zhang Lei
;
Zhou Fan
;
Zhang Laitao
;
Peng Lizhi
;
Guo Cuiping
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Artemisinin
Memantine
Neuroprotection
N-Methyl-D-aspartate(NMDA) receptor
Depression
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