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科研机构
上海药物研究所 [80]
内容类型
期刊论文 [78]
会议论文 [2]
发表日期
2020 [3]
2019 [6]
2018 [2]
2016 [12]
2015 [6]
2014 [7]
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Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening
期刊论文
BIOMOLECULES, 2021, 卷号: 11, 期号: 7, 页码: 14
作者:
Zhou, Qingtong
;
Guo, Wanjing
;
Dai, Antao
;
Cai, Xiaoqing
;
Vass, Marton
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/08/17
GLP-1R
virtual screening
allosteric modulator
drug discovery
molecular docking
A proton-coupled organic cation antiporter is involved in the blood-brain barrier transport of Aconitum alkaloids
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 252, 页码: 9
作者:
Cong, Jiaojiao
;
Ruan, Yiling
;
Lyu, Qinglin
;
Qin, Xiaohui
;
Qi, Xinming
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Aconitum alkaloids
Blood-brain barrier
Proton-coupled organic cation antiporter
hCMEC/D3 cells
Drug transport
Sweroside promotes osteoblastic differentiation and mineralization via interaction of membrane estrogen receptor-alpha and GPR30 mediated p38 signalling pathway on MC3T3-E1 cells
期刊论文
PHYTOMEDICINE, 2020, 卷号: 68, 页码: 12
作者:
Wu, Qing-Chang
;
Tang, Xi-Yang
;
Dai, Zi-Qin
;
Dai, Yi
;
Xiao, Hui-Hui
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/07/01
Sweroside
Differentiation and mineralization
Membrane estrogen receptor-alpha
GPR30
P38 signaling pathway
MC3T3-E1 cells
Antitumor effects of rafoxanide in diffuse large B cell lymphoma via the PTEN/PI3K/Akt and JNK/c-Jun pathways
期刊论文
LIFE SCIENCES, 2020, 卷号: 243, 页码: 11
作者:
He, Wan
;
Xu, Zhijian
;
Song, Dongliang
;
Zhang, Hui
;
Li, Bo
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2020/07/01
Diffuse large B-cell lymphoma
Rafoxanide
PTEN/PI3K/AKT
Apoptosis
DNA damage
Recent progress in drug delivery
期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1145-1162
作者:
Li, Chong
;
Wang, Jiancheng
;
Wang, Yiguang
;
Gao, Huile
;
Wei, Gang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Pharmaceutics
Drug delivery system
Basic research
Application
Delivery strategy
The antifungal activity and mechanisms of action of quantified extracts from berries, leaves and roots of Phytolacca tetramera
期刊论文
PHYTOMEDICINE, 2019, 卷号: 60, 页码: 9
作者:
Butassi, Estefania
;
Svetaz, Laura A.
;
Zhou, Shuaizhen
;
Wolfender, Jean-Luc
;
Cortes, Juan C. G.
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
Phytolacca tetramera
Quantified extracts
Candida albicans
Candida glabrata
Phytolaccagenin
Phytolaccoside B
Genomic and GeneChip expression profiling reveals the inhibitory effects of Amorphophalli Rhizoma in TNBC cells
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 235, 页码: 206-218
作者:
Wu, Chunyu
;
Chen, Mingcang
;
Zhang, Qiuhua
;
Yu, Linghong
;
Zhu, Jiayan
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Gene chip
Amorphophalli Rhizoma
Triple-negative breast cancer
IPA
Deeper Chemical Perceptions for Better Traditional Chinese Medicine Standards
期刊论文
ENGINEERING, 2019, 卷号: 5, 期号: 1, 页码: 83-97
作者:
Hou, Jin-Jun
;
Zhang, Jian-Qing
;
Yao, Chang-Liang
;
Bauer, Rudolf
;
Khan, Ikhlas A.
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
Traditional Chinese medicine
Liquid chromatography
Mass spectrometry
Data-dependent acquisition
Chemometrics
Untargeted
Data mining
Quality control
DCZ0814 induces apoptosis and G0/G1 phase cell cycle arrest in myeloma by dual inhibition of mTORC1/2
期刊论文
CANCER MANAGEMENT AND RESEARCH, 2019, 卷号: 11, 页码: 4797-4808
作者:
Kong, Yuanyuan
;
Li, Bo
;
Chang, Shuaikang
;
Gao, Lu
;
Xu, Zhijian
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
DCZ0814
multiple myeloma
mTOR
bone marrow microenvironment
apoptosis
recentprogressindrugdelivery
期刊论文
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1145
作者:
Li Chong
;
Wang Jiancheng
;
Wang Yiguang
;
Gao Huile
;
Wei Gang
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
MESOPOROUS SILICA NANOPARTICLES
IN-VIVO PHARMACOKINETICS
ORAL DELIVERY
SIRNA DELIVERY
TARGETED NANOASSEMBLIES
CANCER-IMMUNOTHERAPY
COMBINATION THERAPY
SENSITIVE VESICLES
MEMBRANE-RECEPTORS
TUMOR PENETRATION
Pharmaceutics
Drug delivery system
Basic research
Application
Delivery strategy
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