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科研机构
上海药物研究所 [387]
内容类型
期刊论文 [383]
会议论文 [3]
专著章节 [1]
发表日期
2021 [28]
2020 [27]
2019 [41]
2018 [17]
2017 [18]
2016 [25]
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Multi-level fingerprinting and cardiomyocyte protection evaluation for comparing polysaccharides from six Panax herbal medicines
期刊论文
CARBOHYDRATE POLYMERS, 2022, 卷号: 277, 页码: 10
作者:
Liu, Jie
;
Wang, Hong-da
;
Yang, Fei-fei
;
Chen, Bo-xue
;
Li, Xue
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2022/01/04
Panax
Polysaccharide
Oligosaccharide spectrum
Untargeted metabolomics
Cardiomyocyte protection
A simple and effective method for identification of Fraxini Cortex from different sources by multi-mode fingerprint combined with chemometrics
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 16
作者:
Long, Huali
;
Yao, Shuai
;
Tian, Wenshuai
;
Hou, Jinjun
;
Lei, Min
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/01/18
chemometrics
Fraxini Cortex
high-performance thin-layer chromatography
multi-mode fingerprint
ultra-high-performance liquid chromatography
Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
Huangjinsan ameliorates adenine-induced chronic kidney disease by regulating metabolic profiling
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 11
作者:
Guo, Yuejiao
;
Liu, Fang
;
Chen, MingCang
;
Tian, Qiang
;
Tian, Xiaoting
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/12/16
chronic kidney disease
Huangjinsan
metabolomics
renoprotection
traditional Chinese medicine
Quantitative proteomic analysis uncovers inhibition of melanin synthesis by silk fibroin via MITF/tyrosinase axis in B16 melanoma cells
期刊论文
LIFE SCIENCES, 2021, 卷号: 284, 页码: 7
作者:
Wang, Yuqiu
;
Duan, Tianbi
;
Hong, Minhua
;
Zhou, Yanting
;
Huang, Hui
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/11/04
Silk fibroin
Quantitative proteomics
Melanin
Microphthalmia-associated transcription factor
Tyrosinase
Single cell Raman spectroscopy to identify different stages of proliferating human hepatocytes for cell therapy
期刊论文
STEM CELL RESEARCH & THERAPY, 2021, 卷号: 12, 期号: 1, 页码: 12
作者:
Ma, Chen
;
Zhang, Ludi
;
He, Ting
;
Cao, Huiying
;
Ren, Xiongzhao
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2021/12/01
Raman spectroscopy
Cell therapy
Identification
Proliferating human hepatocytes
Dedifferentiation
Two New Cytotoxic Maytansinoids Targeting Tubulin from Trewia nudiflora
期刊论文
PLANTA MEDICA, 2021, 页码: 7
作者:
Lei, Chun
;
Li, Ya-Nan
;
Li, Jia-Nan
;
Zhou, Yu-Bo
;
Cui, Ming-Jun
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/12/16
Trewia nudiflora
Euphorbiaceae
maytansinoids
cytotoxicity
tubulin polymerization
Progression and Regression of Abdominal Aortic Aneurysms in Mice
期刊论文
CURRENT MEDICAL SCIENCE, 2021, 页码: 8
作者:
Ding, Yu-chao
;
Zhang, Xian-jing
;
Zhang, Ji-xiu
;
Zhai, Zi-yi
;
Zhang, Mei-xia
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/12/01
abdominal aortic aneurysm
disease progression
disease regression
elastogenesis
lysyl oxidase
Nyctinastic herbs decoction improves para-chlorophenylalanine-induced insomnia by regulating the expression level of neurotransmitters
期刊论文
ANNALS OF TRANSLATIONAL MEDICINE, 2021, 卷号: 9, 期号: 20, 页码: 16
作者:
Yang, Yiwen
;
Wu, You
;
Xu, Peiqin
;
Guo, Fan
;
Guo, Fei
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/12/16
Nyctinastic herbs decoction (NHD)
para-chlorophenylalanine (PCPA)
insomnia
electroencephalograph (EEG)
behavior
neurotransmitters
A hybrid framework for improving uncertainty quantification in deep learning-based QSAR regression modeling
期刊论文
JOURNAL OF CHEMINFORMATICS, 2021, 卷号: 13, 期号: 1, 页码: 17
作者:
Wang, Dingyan
;
Yu, Jie
;
Chen, Lifan
;
Li, Xutong
;
Jiang, Hualiang
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/11/04
Uncertainty quantification
Quantitative structure-activity relationship
Bayesian neural network
Applicability domain
Bayesian inference
Error prediction
Artificial intelligence
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