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科研机构
上海药物研究所 [23]
内容类型
期刊论文 [23]
发表日期
2019 [1]
2017 [1]
2016 [2]
2015 [3]
2014 [2]
2013 [1]
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Development of Small-Molecules Targeting Receptor Activator of Nuclear Factor-kappa B Ligand (RANKL)-Receptor Activator of Nuclear Factor-kappa B (RANK) Protein-Protein Interaction by Structure-Based Virtual Screening and Hit Optimization
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5370-5381
作者:
Jiang, Min
;
Peng, Lei
;
Yang, Kai
;
Wang, Tianqi
;
Yan, Xueming
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
GPCR Activation and Endocytosis Induced by a 2D Material Agonist
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2017, 卷号: 9, 期号: 17, 页码: 14709-14715
作者:
Dou, Wei-Tao
;
Kong, Ya
;
He, Xiao-Peng
;
Chen, Guo-Rong
;
Zang, Yi
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
2D material
G protein-coupled receptor
ligand
peptide
fluorescence
imaging
photodynamic therapy
endocytosis
Acid-Activatable Versatile Micelleplexes for PD-L1 Blockade Enhanced Cancer Photodynamic Immunotherapy
期刊论文
NANO LETTERS, 2016, 卷号: 16, 期号: 9, 页码: 5503-5513
作者:
Wang, Dangge
;
Wang, Tingting
;
Liu, Jianping
;
Yu, Haijun
;
Jiao, Shi
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Micelleplexes
acid-activatable
photodynamic therapy
cancer immunotherapy
RNA interference
Computational insights into different inhibition modes of the kappa-opioid receptor with antagonists LY2456302 and JDTic
期刊论文
RSC ADVANCES, 2016, 卷号: 6, 期号: 17, 页码: 13626-13635
作者:
Cheng, Jianxin
;
Li, Weihua
;
Liu, Guixia
;
Zhu, Weiliang
;
Tang, Yun
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
WSS25, a sulfated polysaccharide, inhibits RANKL-induced mouse osteoclast formation by blocking SMAD/ID1 signaling
期刊论文
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 9, 页码: 1053-1064
作者:
Chen, Cheng
;
Qin, Yi
;
Fang, Jian-ping
;
Ni, Xin-yan
;
Yao, Jian
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
WSS25
polysaccharides
osteoclast
RANKL
BMP-2
Smad1/5/8
Id1
ovariectomized mice
osteoporosis
(5R)-5-Hydroxytriptolide (LLDT-8) inhibits osteoclastogenesis via RANKL/RANK/OPG signaling pathway
期刊论文
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2015, 卷号: 15
作者:
Shen, Yi
;
Jiang, Ting
;
Wang, Rongsheng
;
He, Shijun
;
Guo, Mengru
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
(5R)-5-Hydroxytriptolide
Osteoclastogenesis
Osteoprotegerin
RANKL
Rheumatoid arthritis
wss25asulfatedpolysaccharideinhibitsranklinducedmouseosteoclastformationbyblockingsmadid1signaling
期刊论文
actapharmacologicasinica, 2015, 卷号: 36, 期号: 9, 页码: 1053
作者:
Chen Cheng
;
Qin Yi
;
Fang Jianping
;
Ni Xinyan
;
Yao Jian
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/07/01
KAPPA-B LIGAND
BONE-FORMATION
RECEPTOR ACTIVATOR
CATHEPSIN-K
T-CELLS
DIFFERENTIATION
RESORPTION
OSTEOPOROSIS
PROTEINS
MICE
WSS25
polysaccharides
osteoclast
RANKL
BMP-2
Smad1/5/8
Id1
ovariectomized mice
osteoporosis
Structures and mechanism for the design of highly potent glucocorticoids
期刊论文
CELL RESEARCH, 2014, 卷号: 24, 期号: 6, 页码: 713-726
作者:
He, Yuanzheng
;
Yi, Wei
;
Suino-Powell, Kelly
;
Zhou, X. Edward
;
Tolbert, W. David
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
glucocorticoids
glucocorticoid receptor
potency
cortisol
mometasone furoate
Studies on the mechanism underlying the inhibition of RANKL-induced differentiation of RAW264.7 cells into osteoclasts by sulfated amylopectin
期刊论文
Chinese Journal New Drugs, 2014, 卷号: 23, 期号: 1, 页码: 25-31
作者:
Chen Cheng
;
Fang Jianping
;
Wang Ying
;
Wang Haiying
;
Ding Kan
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
IkappaBalpha
ERK
sulfated amylopectin
nuclear factor kappa B ligand
osteoclast
IkappaBalpha
ERK
Inducement of Cytokine Release by GFPBW2, a Novel Polysaccharide from Fruit Bodies of Grifola frondosa, through Dectin-1 in Macrophages
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2013, 卷号: 61, 期号: 47, 页码: 11400-11409
作者:
Wang, Ying
;
Fang, Jianping
;
Ni, Xinyan
;
Li, Jie
;
Liu, Qin
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
antitumor activity
beta-glucan
biological response modifier
maitake
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