CORC

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CORC

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SL010110, a lead compound, inhibits gluconeogenesis via SIRT2-p300-mediated PEPCK1 degradation and improves glucose homeostasis in diabetic mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:  Ren, Yu-ran;  Ye, Yang-liang;  Feng, Ying;  Xu, Ti-fei;  Shen, Yu
收藏  |  浏览/下载：22/0  |  提交时间：2021/05/24
Determination of the antidiabetic chemical basis of Phellodendri Chinensis Cortex by integrating hepatic disposition in vivo and hepatic gluconeogenese inhibition in vitro 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 263, 页码: 10
作者:  Tian, Xiaoting;  Xu, Zhou;  Hu, Pei;  Yu, Yanyan;  Li, Zhixiong
收藏  |  浏览/下载：74/0  |  提交时间：2020/12/21
Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway 期刊论文
MOLECULAR METABOLISM, 2020, 卷号: 41, 页码: 15
作者:  Liu, Siwen;  Huang, Suling;  Wu, Xingde;  Feng, Ying;  Shen, Yu
收藏  |  浏览/下载：55/0  |  提交时间：2020/12/24
Sustained ER stress promotes hyperglycemia by increasing glucagon action through the deubiquitinating enzyme USP14 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 卷号: 116, 期号: 43, 页码: 21732-21738
作者:  Liu, Bin;  Zhang, Zhijian;  Hu, Yanyun;  Lu, Yan;  Li, Duanzhuo
收藏  |  浏览/下载：59/0  |  提交时间：2020/07/01
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1193-1204
作者:  Zhou, Ting-ting;  Zhao, Tong;  Ma, Fei;  Zhang, Yi-nan;  Jiang, Jing
收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01
A preclinical overview of metformin for the treatment of type 2 diabetes 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2018, 卷号: 106, 页码: 1227-1235
作者:  Zhou, Tingting;  Xu, Xin;  Du, Mengfan;  Zhao, Tong;  Wang, Jiaying
收藏  |  浏览/下载：46/0  |  提交时间：2019/01/08
HS218 as an FXR antagonist suppresses gluconeogenesis by inhibiting FXR binding to PGC-1α promoter 期刊论文
Metabolism: clinical and experimental, 2018, 卷号: 85, 页码: 126-138
作者:  Xu, Xin;  Shi, Xiaofan;  Chen, Yidi;  Zhou, Tingting;  Wang, Jiaying
收藏  |  浏览/下载：69/0  |  提交时间：2019/01/08
HS218 as an FXR antagonist suppresses gluconeogenesis by inhibiting FXR binding to PGC-1 alpha promoter 期刊论文
METABOLISM-CLINICAL AND EXPERIMENTAL, 2018, 卷号: 85, 页码: 126-138
作者:  Xu, Xin;  Shi, Xiaofan;  Chen, Yidi;  Zhou, Tingting;  Wang, Jiaying
收藏  |  浏览/下载：5/0  |  提交时间：2020/07/01
Discovery and structure-activity relationships study of thieno[2,3-b] pyridine analogues as hepatic gluconeogenesis inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 307-317
作者:  Ma, Fei;  Liu, Jian;  Zhou, Tingting;  Lei, Min;  Chen, Jing
收藏  |  浏览/下载：79/0  |  提交时间：2019/01/08
TSPA as a novel ATF6 alpha translocation inducer efficiently ameliorates insulin sensitivity restoration and glucose homeostasis in db/db mice 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 499, 期号: 4, 页码: 948-953
作者:  Zhou, Tingting;  Cheng, Yanhua;  Yan, Wenzhong;  Shi, Xiaofan;  Xu, Xin
收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08

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