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科研机构
上海药物研究所 [71]
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期刊论文 [71]
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2021 [7]
2020 [5]
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GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhang, Qing
;
Chen, Lin-hai
;
Yang, Hui
;
Fang, You-chen
;
Wang, Si-wei
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/01/18
GPR84
medium chain fatty acid receptor
GPCR
inflammatory bowel diseases
ulcerative colitis
NLRP3 inflammasome
macrophages
GPR160 is a potential biomarker associated with prostate cancer
期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 3
作者:
Guo, Wanjing
;
Zhang, Junyu
;
Zhou, Yan
;
Zhou, Caihong
;
Yang, Yunjie
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/08/17
Design, synthesis and pharmacological evaluation of tricyclic derivatives as selective RXFP4 agonists
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 17
作者:
Lin, Lin
;
Lin, Guangyao
;
Zhou, Qingtong
;
Bathgate, Ross A. D.
;
Gong, Grace Qun
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/08/17
Synthesis
Structure-activity relationship
Relaxin family peptide receptor 4
Selective agonist
Molecular docking
The Two Formyl Peptide Receptors Differently Regulate GPR84-Mediated Neutrophil NADPH Oxidase Activity
期刊论文
JOURNAL OF INNATE IMMUNITY, 2021, 页码: 15
作者:
Martensson, Jonas
;
Sundqvist, Martina
;
Manandhar, Asmita
;
Leremias, Loukas
;
Zhang, Linjie
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/05/24
Neutrophils
G protein-coupled receptors
Cross-talk
Nicotine adenine dinucleotide phosphate oxidase
A novel GPR120-selective agonist promotes insulin secretion and improves chronic inflammation
期刊论文
LIFE SCIENCES, 2021, 卷号: 269, 页码: 8
作者:
Yang, Liu
;
Lei, Xian-Tao
;
Huang, Qi
;
Wang, Ting
;
Sun, Hong-Bin
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
GPR120 agonist
Insulin secretion
Anti-inflammation
Insulin resistance
Type 2 diabetes mellitus
GPR52 Antagonist Reduces Huntingtin Levels and Ameliorates Huntington's Disease-Related Phenotypes
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 2, 页码: 941-957
作者:
Wang, Congcong
;
Zhang, Yu-Fang
;
Guo, Shimeng
;
Zhao, Quan
;
Zeng, Yanping
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
Structures of the glucocorticoid-bound adhesion receptor GPR97-G(o) complex
期刊论文
NATURE, 2021, 页码: 35
作者:
Ping, Yu-Qi
;
Mao, Chunyou
;
Xiao, Peng
;
Zhao, Ru-Jia
;
Jiang, Yi
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
Modulation of the G-Protein-Coupled Receptor 84 (GPR84) by Agonists and Antagonists
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 24, 页码: 15399-15409
作者:
Chen, Lin-Hai
;
Zhang, Qing
;
Xie, Xin
;
Nan, Fa-Jun
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2021/05/24
Targeted Proteomics Combined with Affinity Mass Spectrometry Analysis Reveals Antagonist E7 Acts As an Intracellular Covalent Ligand of Orphan Receptor GPR52
期刊论文
ACS CHEMICAL BIOLOGY, 2020, 卷号: 15, 期号: 12, 页码: 3275-3284
作者:
Ma, Mengna
;
Guo, Shimeng
;
Lin, Xi
;
Li, Shanshan
;
Wu, Yiran
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/05/24
GPR91, a critical signaling mechanism in modulating pathophysiologic processes in chronic illnesses
期刊论文
FASEB JOURNAL, 2020, 页码: 15
作者:
Li, Xinyi
;
Xie, Li
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/24
G protein-coupled receptor
innate immunity
metabolic regulation
succinate
SUCNR1
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