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科研机构
上海药物研究所 [325]
内容类型
期刊论文 [321]
会议论文 [2]
学位论文 [2]
发表日期
2021 [19]
2020 [20]
2019 [14]
2018 [22]
2017 [18]
2016 [20]
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Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Zou, Hui-xi
;
Zhang, Yu-feng
;
Zhong, Da-fang
;
Jiang, Yong
;
Liu, Fei
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/01/04
furmonertinib
autoinduction
food effect
alkaline phosphatase
body weight
pharmacokinetics
modeling and simulation
NSCLC
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:
Wang, Shuni
;
Yang, Hong
;
Su, Mingbo
;
Lian, Fulin
;
Cong, Zhanqing
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2021/11/04
NSD2
Methyltransferase
HTS
Multiple myeloma
5-Aminonaphthalene derivatives
Inhibitor
Synthesis and bioactivity studies of covalent inhibitors derived from (-)-Chaetominine
期刊论文
JOURNAL OF MOLECULAR STRUCTURE, 2021, 卷号: 1241, 页码: 14
作者:
Zhou, Xian
;
Feng, Xuexin
;
Wang, Dachi
;
Chen, Deheng
;
Wu, Gaoxing
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2021/08/17
Chaetominine
Cellular growth inhibition
Cancer cell line
Covalent warhead
Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel alpha-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 115, 页码: 17
作者:
Xie, Hong-Xu
;
Zhang, Juan
;
Li, Yue
;
Zhang, Jin-He
;
Liu, Shan-Kui
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/11/04
Tetrahydrobenzo[b]thiophen-2-yl)urea
alpha-Glucosidase inhibitors
Non-competitive inhibitor
Molecular docking
Anti-hyperglycaemic activity
Type 2 diabetes
Design and Synthesis of Alkyl Phenols Inhibitors of Death Associated Apoptotic Protein Kinase 2 (DRAK2)
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3204-3213
作者:
Zheng Zhang
;
Dai Chengqiu
;
Wu Honghong
;
Li Jingya
;
Nan Fajun
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/11/04
death associated apoptotic protein kinase 2
diabetes
alkylphenols
inhibitors
Structurally diverse diterpenoid alkaloids from the lateral roots of Aconitum carmichaelii Debx. and their anti-tumor activities based on in vitro systematic evaluation and network pharmacology analysis
期刊论文
RSC ADVANCES, 2021, 卷号: 11, 期号: 43, 页码: 26594-26606
作者:
Yu, Yang
;
Wu, Shifei
;
Zhang, Jianqing
;
Li, Jiayuan
;
Yao, Changliang
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  |  
浏览/下载:28/0
  |  
提交时间:2021/11/04
Anti-neuroinflammatory activity of Shenqi Fuzheng Injection and its main active constituents
期刊论文
BIOSCIENCE TRENDS, 2021, 卷号: 15, 期号: 4, 页码: 231-239
作者:
Wang, Wenwen
;
Zhang, Zijia
;
Deng, Yanping
;
Yang, Zhixin
;
Hou, Jinjun
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  |  
浏览/下载:68/0
  |  
提交时间:2021/11/04
Neuroinflammation
Shenqi Fuzheng Injection (SFI)
Arginase 1 (Arg1)
Transforming growth factor beta-1 (Tgfb1)
microglia
Iridoid Constituents of Viburnum brachybotryum
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 7, 页码: 1915-1923
作者:
Rao, Li
;
Li, Yao
;
He, Qian
;
Liu, Yu
;
Su, Yu
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/11/04
Dimeric 9,10-dihydrophenanthrene derivatives from Bletilla striata and their atropisomeric nature
期刊论文
FITOTERAPIA, 2021, 卷号: 152, 页码: 7
作者:
Sui, Jian
;
Tang, Chunping
;
Ke, Chang-Qiang
;
Ye, Yang
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2021/08/17
Bletilla striata
Phenanthrene
bibenzyl atropisomer
LC-CD
Bletistriatins A-D
Bi(9
10-dihydro)phenanthrene
Clerodenoids A-F: C-ring Aromatized and/or Rearranged Abietane Diterpenoids from Clerodendrum chinense var. simplex
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 页码: 7
作者:
Qi, Jingjing
;
Zhang, Yan
;
Liu, Qunfang
;
Liu, Hongchun
;
Fan, Yaoyue
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/08/17
Clerodendrum chinense
Natural products
Diterpenoids
Structural elucidation
Antiproliferative activities
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