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浏览/检索结果: 共9条，第1-9条 帮助 限定条件 专题：北京大学    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Serotonin 5-HT6 receptors affect cognition in a mouse model of Alzheimer's disease by regulating cilia function 期刊论文 ALZHEIMERS RESEARCH & THERAPY, 2017 Hu, Lili; Wang, Bingjie; Zhang, Yan 收藏  |  浏览/下载：4/0  |  提交时间：2017/12/03 5-HT6  Cilia  Axon  Axon initial segment  Alzheimer&apos  BARDET-BIEDL-SYNDROME  TYPE-3 ADENYLYL-CYCLASE  AXON INITIAL SEGMENT  ASSOCIATION ANALYSIS  POLYMORPHISM C267T  NEURONAL CILIA  RAT-BRAIN  LOCALIZATION  ANTAGONIST  MEMORY  s disease   Deacetylation of TFEB promotes fibrillar A beta degradation by upregulating lysosomal biogenesis in microglia 期刊论文 PROTEIN & CELL, 2016 Bao, Jintao; Zheng, Liangjun; Zhang, Qi; Li, Xinya; Zhang, Xuefei; Li, Zeyang; Bai, Xue; Zhang, Zhong; Huo, Wei; Zhao, Xuyang; Shang, Shujiang; Wang, Qingsong; Zhang, Chen; Ji, Jianguo 收藏  |  浏览/下载：7/0  |  提交时间：2017/12/03 Alzheimer&apos  microglia  lysosomes  TFEB  SIRT1  deacetylation  AMYLOID PLAQUE PATHOGENESIS  ALZHEIMERS-DISEASE  MOUSE MODEL  IN-VIVO  AUTOPHAGY  SIRT1  CLEARANCE  ACTIVATION  EXPRESSION  MECHANISMS  s disease   Selective filtering defect at the axon initial segment in Alzheimer's disease mouse models 期刊论文 proceedings of the national academy of sciences of the united states of america, 2014 Sun, Xiaqin; Wu, Yu; Gu, Mingxue; Liu, Zhuo; Ma, Yuanlin; Li, Jun; Zhang, Yan 收藏  |  浏览/下载：1/0  |  提交时间：2015/11/11 AMYLOID-BETA  NEURONAL POLARITY  IN-VIVO  PROTEIN  PRESENILIN-1  TRANSPORT  ANKYRIN(G)  GENE  CONTRIBUTES  MAINTENANCE   miR-342-5p Decreases Ankyrin G Levels in Alzheimer's Disease Transgenic Mouse Models 期刊论文 cell reports, 2014 Sun, Xiaqin; Wu, Yu; Gu, Mingxue; Zhang, Yan 收藏  |  浏览/下载：4/0  |  提交时间：2015/11/11 AXON INITIAL SEGMENT  AMYLOID PRECURSOR PROTEIN  NEURODEGENERATIVE DISEASES  NEURONAL POLARITY  EXPRESSION  TRANSPORT  MICRORNAS  BRAIN  GENE  IDENTIFICATION   Quantitative proteomics reveals that PEA15 regulates astroglial A beta phagocytosis in an Alzheimer's disease mouse model 期刊论文 journal of proteomics, 2014 Lv, Junniao; Ma, Shuaipeng; Zhang, Xuefei; Zheng, Liangjun; Ma, Yuanhui; Zhao, Xuyang; Lai, Wenjia; Shen, Hongyan; Wang, Qingsong; Ji, Jianguo 收藏  |  浏览/下载：3/0  |  提交时间：2015/11/10 Quantitative proteomics  PEA15  A beta  Phagocytosis  Alzheimer&apos  APP/PS1 mouse  MIGRATION INHIBITORY FACTOR  AMYLOID-BETA  GLUTAMINE-SYNTHETASE  ASTROCYTE MIGRATION  GLIOMA-CELLS  IN-VITRO  PROTEIN  CLEARANCE  PEA-15  EXPRESSION  s disease   MiR-206 decreases brain-derived neurotrophic factor levels in a transgenic mouse model of Alzheimer's disease 期刊论文 神经科学通报, 2014 Tian, Ning; Cao, Zeyuan; Zhang, Yan 收藏  |  浏览/下载：3/0  |  提交时间：2015/11/11 miR-206  brain-derived neurotrophic factor  APP/PS1  cell death  Alzheimer&apos  MILD COGNITIVE IMPAIRMENT  INDUCED ARC EXPRESSION  INTRACELLULAR AMYLOID TOXICITY  HUMAN PRIMARY NEURONS  CORTICAL-NEURONS  SIGNALING PATHWAYS  BDNF  BETA  PROTEIN  MICRORNAS  s disease   Reactive oxidative species enhance amyloid toxicity in APP/PS1 mouse neurons 期刊论文 神经科学通报, 2012 Yang, Bin; Sun, Xiaqin; Lashuel, Hilal; Zhang, Yan 收藏  |  浏览/下载：4/0  |  提交时间：2015/11/11 amyloid  reactive oxidative species  APP/ PS1  aggregation  toxicity  ALZHEIMERS-DISEASE  TRANSGENIC MICE  BETA-PEPTIDE  A-BETA-42 ACCUMULATION  PRECURSOR PROTEIN  PLAQUE-FORMATION  STRESS  APOPTOSIS  PATHOLOGY  OLIGOMERS   GABA Attenuates Amyloid Toxicity by Downregulating its Endocytosis and Improves Cognitive Impairment 期刊论文 journal of alzheimers disease, 2012 Sun, Xiaqin; Meng, Xiaolu; Zhang, Jie; Li, Yonghui; Wang, Liping; Qin, Xiaoyan; Sui, Nan; Zhang, Yan 收藏  |  浏览/下载：2/0  |  提交时间：2015/11/13 Amyloid-beta  cell death  cognitive impairment  endocytosis  GABA  ALZHEIMERS-DISEASE  SENILE DEMENTIA  APP/PS1 MICE  RECEPTOR  RAGE  BETA  BURDEN  BRAIN  POSTMORTEM  ANTIBODY   Morphine Protects against Intracellular Amyloid Toxicity by Inducing Estradiol Release and Upregulation of Hsp70 期刊论文 journal of neuroscience, 2011 Cui, Jia; Wang, Yunfeng; Dong, Qiping; Wu, Shimin; Xiao, Xianzhong; Hu, Jianying; Chai, Zhen; Zhang, Yan 收藏  |  浏览/下载：2/0  |  提交时间：2015/11/13 HIPPOCAMPAL ESTROGEN SYNTHESIS  RANDOMIZED CONTROLLED-TRIAL  HEALTH INITIATIVE MEMORY  PRIMARY HUMAN NEURONS  ALZHEIMERS-DISEASE  POSTMENOPAUSAL WOMEN  REPLACEMENT THERAPY  COGNITIVE FUNCTION  PLUS PROGESTIN  RAT-BRAIN