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浏览/检索结果: 共12条，第1-10条 帮助 限定条件 专题：北京大学    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Gene mutation analysis of 175 Chinese patients with early-onset epileptic encephalopathy 期刊论文 CLINICAL GENETICS, 2017 Zhang, Q.; Li, J.; Zhao, Y.; Bao, X.; Wei, L.; Wang, J. 收藏  |  浏览/下载：4/0  |  提交时间：2017/12/03 CDKL5  early-onset epileptic encephalopathy  KCNQ2  recommending treatment  targeted next-generation sequencing  KCNQ2 ENCEPHALOPATHY  POTASSIUM CHANNEL  CDKL5  SPECTRUM  LOCALIZATION  EPILEPSIES  QUINIDINE  INFANCY  GAIN   TRPV1：一种同时参与慢性痛外周敏化和疼痛中枢调制的重要分子 期刊论文 生理学报, 2017 张瑛; 王韵 收藏  |  浏览/下载：6/0  |  提交时间：2017/12/03 疼痛  磷酸化  Tat穿膜肽  镇痛  TRPV1   A Hybrid Chalcone Combining the Trimethoxyphenyl and Isatinyl Groups Targets Multiple Oncogenic Proteins and Pathways in Hepatocellular Carcinoma Cells 期刊论文 PLOS ONE, 2016 Cao, Lili; Zhang, Lijun; Zhao, Xiang; Zhang, Ye 收藏  |  浏览/下载：14/0  |  提交时间：2017/12/04 CANCER-CELLS  TUBULIN POLYMERIZATION  BIOLOGICAL EVALUATION  MUTATIONAL LANDSCAPE  MOLECULAR THERAPIES  ANTITUBULIN AGENTS  IN-VIVO  NUCLEOLIN  KINASE  IDENTIFICATION   Identification of YPL014W (Cip1) as a novel negative regulator of cyclin-dependent kinase in Saccharomyces cerevisiae 期刊论文 GENES TO CELLS, 2016 Ren, Ping; Malik, Asrar; Zeng, Fanli 收藏  |  浏览/下载：4/0  |  提交时间：2017/12/04 CELL-CYCLE  SCHIZOSACCHAROMYCES-POMBE  FUNCTIONAL HOMOLOGS  INHIBITORY DOMAIN  DNA-REPLICATION  BUDDING YEAST  G1 CYCLIN  PROTEIN  G(1)  SIC1   Phosphorylation of TRPV1 by cyclin-dependent kinase 5 promotes TRPV1 surface localization, leading to inflammatory thermal hyperalgesia 期刊论文 EXPERIMENTAL NEUROLOGY, 2015 Liu, Jiao; Du, Junxie; Yang, Yanrui; Wang, Yun 收藏  |  浏览/下载：4/0  |  提交时间：2017/12/03 Cdk5  TRPV1  Phosphorylation  Membrane trafficking  Hyperalgesia  PRIMARY SENSORY NEURONS  MORPHINE ANTINOCICEPTIVE TOLERANCE  CDK5 INHIBITORY PEPTIDE  PROTEIN-KINASE  HEAT HYPERALGESIA  NEUROTRANSMITTER RELEASE  NEURITE OUTGROWTH  PLASMA-MEMBRANE  NERVOUS-SYSTEM  FHA DOMAIN   周期素依赖性蛋白激酶5通过磷酸化AP2μ2干扰TRPV1内吞进而调控炎症热痛觉敏化 其他 2015-01-01 刘皎; 杜军霞; 王韵 收藏  |  浏览/下载：3/0  |  提交时间：2017/12/03 炎症热痛敏  磷酸化  Cdk5  TRPV1  AP2μ2   Deactivation of excitatory neurons in the prelimbic cortex via Cdk5 promotes pain sensation and anxiety 期刊论文 NATURE COMMUNICATIONS, 2015 Wang, Guo-Qiang; Cen, Cheng; Li, Chong; Cao, Shuai; Wang, Ning; Zhou, Zheng; Liu, Xue-Mei; Xu, Yu; Tian, Na-Xi; Zhang, Ying; Wang, Jun; Wang, Li-Ping; Wang, Yun 收藏  |  浏览/下载：3/0  |  提交时间：2017/12/03 MEDIAL PREFRONTAL CORTEX  CHRONIC NEUROPATHIC PAIN  COGNITIVE IMPAIRMENT  CINGULATE CORTEX  MECHANISMS  DEPRESSION  EXCITABILITY  NOCICEPTION  MODULATION  DISORDERS   Multiple mechanisms determine the order of APC/C substrate degradation in mitosis 期刊论文 journal of cell biology, 2014 Lu, Dan; Hsiao, Jennifer Y.; Davey, Norman E.; Van Voorhis, Vanessa A.; Foster, Scott A.; Tang, Chao; Morgan, David O. 收藏  |  浏览/下载：3/0  |  提交时间：2015/11/11 SPINDLE-ASSEMBLY CHECKPOINT  ANAPHASE-PROMOTING COMPLEX  SISTER-CHROMATID SEPARATION  SACCHAROMYCES-CEREVISIAE  BUDDING YEAST  CYCLIN-A  CELL-CYCLE  MITOTIC EXIT  DEPENDENT PROTEOLYSIS  PROTEIN-KINASE   Clinical features and gene mutational spectrum of CDKL5-related diseases in a cohort of Chinese patients 期刊论文 bmc medical genetics, 2014 Zhao, Ying; Zhang, Xiaoying; Bao, Xinhua; Zhang, Qingping; Zhang, Jingjing; Cao, Guangna; Zhang, Jie; Li, Jiarui; Wei, Liping; Pan, Hong; Wu, Xiru 收藏  |  浏览/下载：10/0  |  提交时间：2015/11/10 CDKL5 mutations  Early-onset epileptic encephalopathy  X chromosome inactivation  ONSET INTRACTABLE EPILEPSY  X-CHROMOSOME INACTIVATION  CDKL5 MUTATIONS  RETT-SYNDROME  INFANTILE SPASMS  MENTAL-RETARDATION  SEVERE ENCEPHALOPATHY  FEMALE-PATIENTS  BOYS  SEIZURES   Mechanism of chromosomal DNA replication initiation and replication fork stabilization in eukaryotes 期刊论文 science china life sciences, 2014 Wu LiHong; Liu Yang; Kong DaoChun 收藏  |  浏览/下载：1/0  |  提交时间：2015/11/10 DNA replication origins  pre-RC assembly  replication fork stability  S phase checkpoint  ORIGIN RECOGNITION COMPLEX  CYCLIN-DEPENDENT KINASE  S-PHASE CHECKPOINT  SCHIZOSACCHAROMYCES-POMBE  FISSION YEAST  SACCHAROMYCES-CEREVISIAE  MULTIPLE MECHANISMS  FRAGILE SITES  CELL-CYCLE  BINDING