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浏览/检索结果: 共98条，第1-10条 帮助 限定条件 发表日期：2020    内容类型：期刊论文    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP-Protein Interactions in Kidney Cancer Cells 期刊论文 CHINESE JOURNAL OF CHEMISTRY, 2020, 页码: 274-280 作者:  Wang, Zhen;  Zhang, Hao;  Chen, Baoen;  Ouyang, Sisheng;  Zheng, Tong 收藏  |  浏览/下载：125/0  |  提交时间：2021/05/24 SPOP  Protein‐  protein interaction  Clear cell Renal Cell Carcinomas  Crystal structure  Peptide inhibitor   Substitution Effect of the Trifluoromethyl Group on the Bioactivity in Medicinal Chemistry: Statistical Analysis and Energy Calculations 期刊论文 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2020, 卷号: 60, 期号: 12, 页码: 6242-6250 作者:  Abula, Amina;  Xu, Zhijian;  Zhu, Zhengdan;  Peng, Cheng;  Chen, Zhaoqiang 收藏  |  浏览/下载：26/0  |  提交时间：2021/05/24 Targeted Proteomics Combined with Affinity Mass Spectrometry Analysis Reveals Antagonist E7 Acts As an Intracellular Covalent Ligand of Orphan Receptor GPR52 期刊论文 ACS CHEMICAL BIOLOGY, 2020, 卷号: 15, 期号: 12, 页码: 3275-3284 作者:  Ma, Mengna;  Guo, Shimeng;  Lin, Xi;  Li, Shanshan;  Wu, Yiran 收藏  |  浏览/下载：16/0  |  提交时间：2021/05/24 Combinatorial Photothermal 3D-Printing Scaffold and Checkpoint Blockade Inhibits Growth/Metastasis of Breast Cancer to Bone and Accelerates Osteogenesis 期刊论文 ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 14 作者:  He, Chao;  Yu, Luodan;  Yao, Heliang;  Chen, Yu;  Hao, Yongqiang 收藏  |  浏览/下载：53/0  |  提交时间：2021/05/24 bone metastasis  breast cancer  checkpoint blockade  immunotherapy  osteogenesis  photothermal therapy   Palladium-mediated Suzuki-Miyaura Cross-Coupling Reaction of Potassium Boc-protected aminomethyltrifluoroborate with DNA-Conjugated aryl bromides for DNA-Encoded chemical library synthesis 期刊论文 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020, 卷号: 533, 期号: 2, 页码: 209-214 作者:  Qu, Yi;  Liu, Sixiu;  Wen, Huanan;  Xu, Yanfen;  An, Yulong 收藏  |  浏览/下载：73/0  |  提交时间：2020/12/24 DNA Encoded chemistry  Suzuki-miyaura cross-coupling  Potassium trifluoroborates   Design, synthesis and anti-tumor activities of carbamate derivatives of cinobufagin 期刊论文 STEROIDS, 2020, 卷号: 164, 页码: 11 作者:  Zhou, Yang;  Hou, Jinjun;  Long, Huali;  Zhang, Zijia;  Lei, Min 收藏  |  浏览/下载：43/0  |  提交时间：2021/05/24 Cardiac glycosides  Cinobufagin  Natural product  Cytotoxicity  Antiproliferative activities   A new method for the synthesis of chalcone derivatives promoted by PPh3/I(2)under non-alkaline conditions 期刊论文 SYNTHETIC COMMUNICATIONS, 2020, 页码: 10 作者:  Xue, Kangsheng;  Sun, Guoxiang 收藏  |  浏览/下载：23/0  |  提交时间：2020/12/24 Aldehyde  chalcone  Claisen-Schmidt reaction  ketone  PPh3  I2   Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7 作者:  Bi, Xiaoyang;  Chen, Yu;  Sun, Zhongya;  Lu, Wenchao;  Xu, Pan 收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24 Drug design  CBP  Bromodomain  Inhibitor  Acute myeloid leukemia   Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 21, 页码: 12748-12772 作者:  Li, Junyou;  Liu, Mengqi;  Li, Yazhou 收藏  |  浏览/下载：24/0  |  提交时间：2021/05/24 Synthesis and biological activity of C-7, C-9 and C-10 modified taxane analogues from 1-deoxybaccatin VI 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 21, 页码: 8 作者:  Xie, Chenghu;  Cui, Yongmei;  Li, Lanlan;  Zhang, Minmin;  Liu, Hongchun 收藏  |  浏览/下载：74/0  |  提交时间：2020/12/21 Paclitaxel  Taxane analogues  1-Deoxybaccatin VI  Synthesis  In vitro anticancer activity